Patent classifications
C
C12
C12N
2760/00
C12N2760/00011
C12N2760/18011
C12N2760/18041
C12N2760/18045
C12N2760/18045
METHODS AND SYSTEMS OF PARTICLE PRODUCTION
20250059560
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2025-02-20
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Provided herein are methods of producing lipid membrane bound particles, such as lentiviral vectors, that contain one or more Paramyxovirus envelope proteins in the lipid bilayer. Also provided are lipid membrane bound particles containing one or more Paramyxovirus envelope proteins in the lipid bilayer. In some embodiments, the one or more Paramyxovirus envelope protein is a Nipah virus (NiV) protein G or F or a biologically active portion or retargeted fusion thereof. In some embodiments, the lipid membrane bound particle is a lentiviral vector. Also provided are related compositions, kits and systems in connection with the provided methods.