Patent classifications
C
C12
C12N
2795/00
C12N2795/00011
C12N2795/14011
C12N2795/14041
C12N2795/14043
C12N2795/14043
M13 BACTERIOPHAGE WITH A HIGH CYSTEINE CONTENT AND GENETICALLY ENGINEERABLE HYDROGELS
20230304025
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2023-09-28
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A genetically engineered bacteriophage that can be crosslinked to form a solid material, for example, a hydrogel.
Targeted genome modification using circular single-stranded DNA
The present invention is directed to methods for generating one or more genetically modified cells by using a circular single stranded DNA (CiSSD) as a donor template and targeting genome modification. These methods include transferring one or more DNA polynucleotides into the cell for site-specific nuclease-mediated DNA repair and selecting one or more cells having the transferred DNA incorporated into the cell's genome.