Provided herein are aptamers that bind specifically to the surface proteins of periodontal pathogens. Also provided herein are methods for detecting and treating periodontal disease in a subject. The method comprises detecting bacteria associated with periodontal disease by use of the present aptamers to analyze a sample taken from a gum pocket of a tooth of the subject; and treating the periodontal disease of the subject by administering to the gum pocket of the tooth a bactericide or an anti-microbial phototherapy to eradicate the bacteria associated with periodontal disease.

Compositions that include: from 5 wt-% to 30 wt-% of one or more plant based oils based on the total weight of the composition; from 70 wt-% to 95 wt-% of an aqueous phase based on the total weight of the composition; from 0.1 wt-% to 5 wt-% of one or more surfactants based on the total weight of the composition; and from 0.05 wt-% to 3 wt-% of a viscosity modifier, wherein the composition has a pH from 4.5 to 9.5, the composition is an oil in water (o/w) emulsion, and the composition is edible. Methods of utilizing disclosed compositions are also included.

A device for the treatment of periodontal disease includes a handle that has a configuration familiar to dental professionals, and a detachable tip or cartridge, that is locked into the handle when use. The device provides for automatically delivering a single dose of medicament, such as a powdered preparation of antibiotic, to a periodontal pocket for treatment of infection or disease.

This application relates to oral hygiene and/teeth cleaning devices and associated methods. The devices can be configured to have a shape that allows all or substantially all of a user's teeth to be cleaned at once. In some embodiments, the devices are configured to be useable, for example, without access to water or a bathroom. The devices can be used to freshen up and clean the user's mouth on-the-go. In some embodiments, the devices are disposable.

An edentulous mouth insert appliance for mounting upon the edentulous gum of a patient, comprises a u-shaped frame formed of a rigid flexible material, with a portion to embrace the gum and a portion extending beyond the gum with an exposed surface to replicate a bite aligned with the corresponding occlusal plane. The frame has a base supporting a pair of inner and outer side walls spaced apart by the base a distance allowing the frame to encircle and cover the edentulous gum with a space between inner surfaces of the frame and the gum. A fill within the frame fills the space between the frame and the gum upon which the appliance is fitted, providing a void-free seal between the apparatus and the gum.

In one aspect, the present application provides an anti-caries film, it contains a fluorine-containing silane, a film-forming agent, and an acidic substance.

Systems and methods are disclosed for fabricating a dental or oral appliance utilizing support structures. A three dimensional representation of the dentition of a patient may be captured and reconfigured for correcting one or more malocclusions. The oral appliance may be printed upon an inner structure which supports the oral appliance during fabrication. The inner structure may be subsequently removed once the oral appliance is completed.

An oral care implement herein may be embodied as an oral device for placement in the oral cavity. The device may include an insert configured for placement in the oral cavity in contact with a wearer's teeth and an activating member configured for placement in the oral cavity and selectively attachable to the insert.

A curable composite material containing nanodiamonds, denture bases and other dental prosthetics made from the composite material and methods for treating dental stomatitis using these prosthetics.

Systems and methods are generally described for an oral hygiene device. The oral hygiene device may include a handle portion and a head portion coupled to the handle portion and including a pick head interface. A pick head may be removably coupled to the pick head interface. The pick head may include a pointed pick member. An image capture device may be disposed in the head portion. The image capture device may be effective to capture image data representing images of an area proximal to a tip of the pointed pick member. A vibration element may be coupled to the pick head interface. The vibration element may be effective to vibrate the pick head.