An example method for cutting a plurality of lenticules from a donor cornea includes receiving a donor cornea, cutting a first layer of a first set of lenticules from the donor cornea, and cutting a second layer of a second set of lenticules from the donor cornea. The lenticules are cut according to a pattern that to maximizes the number of lenticules, thereby maximizing the number of implants from the single donor cornea. An example implant handling device includes a body. The body includes a flattened end configured to receive a corneal implant and keep the corneal implant from rolling or folding. The flattened end has a width and a height, the width being greater than the height. The body includes a slit opening to the flattened end, the slit opening configured to allow the corneal implant to pass into the flattened end.

A method of treating an eye of a patient may include positioning an expandable strut structure within at least one of an internal carotid artery, an ophthalmic artery, or an ostium at a junction between the internal carotid artery and the ophthalmic artery. Additionally, the method may include directing blood flow towards the ophthalmic artery via a diverter element associated with the expandable strut structure.

Equipment and methods for refractive surgery, including for keratoplasty. The invention describes equipment and methods for the production and implantation of a lamella of a tissue or material for the purpose of correcting a corneal geometry at maximum precision that is thus improved in relation to the prior art. The invention facilitates restoration of normal corneal geometry together with optical functionality of the cornea which is improved in relation to the prior art. A planning device, a treatment system and a planning method are designed to couple a device coordinate systems of the laser devices involved and characterization devices by application of registration and to uniquely register the supplied measurement data for generating the lamella to be implanted to the device coordinate systems by a specific, defined edge geometry of a blank from which the lamella is produced, and by the lamella, and by additional system and method aids.

This disclosure provides ophthalmic implants such as sulcus implants which can comprise one or more drug delivery devices. Further provided herein are methods of using the drug delivery ophthalmic devices described herein for implantation into a subject's eye, e.g., into an eye's ciliary sulcus or capsular bag.

Ophthalmic tissue delivery devices that include an injector and injector carriers and methods for endothelial keratoplasty surgical procedures are provided. Injectors include a conduit sized to accommodate ophthalmic tissue. One end of the injector is configured for insertion into a patient's eye to inject ophthalmic tissue. Injector carriers include a container, a cap configured to seal an opening of the container. The injector can be coupled to a pressure actuated valve and a syringe where activating the syringe opens the value and allows fluid to flow from the syringe, through the valve, and through the injector to dispense ophthalmic tissue from the injector into a patient's eye without the need to physically contact the ophthalmic tissue.

A device that facilitates preparation of corneal grafts, including an illuminated base; and a corneal graft holder that can be selectively coupled to the illuminated base to illuminate a portion of donor cornea to facilitate preparation of the corneal graft.

Apparatus and methods are described including illumination equipment (300) configured to direct light into an eye of a subject. An optical device (100) is placed inside the subjects eye, the optical device including a Fabry Perot interferometer (106) comprising at least two mirrors (162, 164), the Fabry Perot interferometer (106) being configured such that a distance between the mirrors (162, 164) varies as an intraocular parameter of the subjects eye varies. A retroreflector (140) is configured such that light that is transmitted through the Fabry Perot interferometer (106) is automatically reflected out of the subjects eye. Readout equipment (400) is configured to detect the light that is reflected out of the subjects eye. Other applications are also described.

A technique can consistently achieve thicknesses of ≤50 μm for corneal tissue for Descemet stripping automated endothelial keratoplasty (DSAEK). Grafts with thicknesses of ≤50 μm are also known as nanothin DSAEK (NT-DSAEK) grafts. Evidence shows that using thinner DSAEK grafts, particularly NT-DSAEK grafts, can significantly improve visual outcomes. According to an example embodiment, a method for producing a corneal graft includes drying a donor cornea to cause a pre-cut thickness of the donor cornea to decrease. The method includes, concurrently with drying the donor cornea, determining pre-cut thickness measurements for the donor cornea. The method includes, in response to the pre-cut thickness measurements indicating the pre-cut thickness of the donor cornea has decreased to a predetermined value, cutting the donor cornea to a post-cut thickness of ≤100 μm, or more particularly ≤50 μm, to produce a corneal graft.

Methods of manufacturing and implanting corneal inlays, such as small diameter corneal inlays, are provided. The methods include manufacturing an implant body to have a meniscus shape with a small diameter and an index of refraction, and implanting the implant body in a corneal bed of a cornea. The inlays cause a change in an anterior surface of the cornea after implantation due to the implant body.

A diffractive multifocal lens is disclosed, comprising an optical element having at least one diffractive surface, the surface profile comprising a plurality of annular concentric zones. The optical thickness of the surface profile changes monotonically with radius within each zone, while a distinct step in optical thickness at the junction between adjacent zones defines a step height. The step heights for respective zones may differ from one zone to another periodically so as to tailor diffraction order efficiencies of the optical element, in one example of a trifocal lens, step heights alternate between two values, the even-numbered step heights being lower than the odd-numbered step heights. By plotting a topographical representation of the diffraction efficiencies resulting from such a surface profile, step heights may be optimized to direct a desired level of light power into the diffraction orders corresponding to near, intermediate, and distance vision, thereby optimizing the performance of the multifocal lens.