The present invention discloses a method for preparing taurine. According to the method, ethylene oxide reacts with hydrosulphite to generate isethionate, after the isethionate and ammonia are subjected to an ammonolysis reaction under a microwave condition, ammonia removal is conducted to obtain a taurine salt solution, the taurine salt solution is converted into a taurine solution through acidification or ion exchange or ion membrane or heating, and taurine is extracted through concentration and crystallization. According to the present invention, the reaction time can be shortened, and the reaction temperature and pressure can be reduced, thereby achieving high yield and reducing energy consumption.

The present invention discloses a method for preparing taurine. According to the method, ethylene oxide reacts with hydrosulphite to generate isethionate, after the isethionate and ammonia are subjected to an ammonolysis reaction under a microwave condition, ammonia removal is conducted to obtain a taurine salt solution, the taurine salt solution is converted into a taurine solution through acidification or ion exchange or ion membrane or heating, and taurine is extracted through concentration and crystallization. According to the present invention, the reaction time can be shortened, and the reaction temperature and pressure can be reduced, thereby achieving high yield and reducing energy consumption.

A method for preparing sodium taurine as a taurine intermediate is provided in the present disclosure. The method comprises the following steps: providing sodium hydroxyethyl sulfonate and an ammonia source; and placing the sodium hydroxyethyl sulfonate and the ammonia source in an aminolysis reactor for an aminolysis reaction to obtain a mixture containing sodium taurine as a taurine intermediate, wherein the molar ratio of ammonia in the ammonia source to the sodium hydroxyethyl sulfonate is greater than or equal to 25:1. A method for preparing taurine is further provided.

A method for preparing sodium taurine as a taurine intermediate is provided in the present disclosure. The method comprises the following steps: providing sodium hydroxyethyl sulfonate and an ammonia source; and placing the sodium hydroxyethyl sulfonate and the ammonia source in an aminolysis reactor for an aminolysis reaction to obtain a mixture containing sodium taurine as a taurine intermediate, wherein the molar ratio of ammonia in the ammonia source to the sodium hydroxyethyl sulfonate is greater than or equal to 25:1. A method for preparing taurine is further provided.

A method and system for preparing high-purity taurine and salt by reacting ethylene oxide with bisulfite to generate isethionate, performing an ammonolysis reaction on the isethionate and ammonia as well as a metal salt, evaporating the reaction solution to obtain a taurine salt concentrated solution, subjecting the concentrated solution to ion exchange in an ion exchange system to obtain an adsorption solution with a main ingredient of taurine, separately collecting the adsorption solution, extracting the taurine from the adsorption solution, eluting adsorbed metal cations from the ion exchange system by an acid, separately collecting the eluate, and extracting salt from the eluate or directly using the eluate as a salt solution product. According to the disclosure, advance separation of materials of two target products is completed after the ammonolysis reaction, and then the target products are separately extracted, so that an extraction process becomes very simple, interference brought to product separation when two target products are positioned in the same maternal system completely does not need to be considered, the process is simple, and the production cost is greatly reduced.

A method and system for preparing high-purity taurine and salt by reacting ethylene oxide with bisulfite to generate isethionate, performing an ammonolysis reaction on the isethionate and ammonia as well as a metal salt, evaporating the reaction solution to obtain a taurine salt concentrated solution, subjecting the concentrated solution to ion exchange in an ion exchange system to obtain an adsorption solution with a main ingredient of taurine, separately collecting the adsorption solution, extracting the taurine from the adsorption solution, eluting adsorbed metal cations from the ion exchange system by an acid, separately collecting the eluate, and extracting salt from the eluate or directly using the eluate as a salt solution product. According to the disclosure, advance separation of materials of two target products is completed after the ammonolysis reaction, and then the target products are separately extracted, so that an extraction process becomes very simple, interference brought to product separation when two target products are positioned in the same maternal system completely does not need to be considered, the process is simple, and the production cost is greatly reduced.

The present invention relates to a liquid detergent composition for textile products containing the following component (A) in an amount of 10% by mass or more and 60% by mass or less), the following component (B), and water: component (A): an internal olefin sulfonate having 17 or more and 24 or less carbon atoms, wherein the mass ratio of an internal olefin sulfonate having 17 or more and 24 or less carbon atoms with the sulfonate group at position 2 or higher and position 4 or lower (IO-1S) to an internal olefin sulfonate having 17 or more and 24 or less carbon atoms with the sulfonate group at position 5 or higher (IO-2S), (IO-1S)/(IO-2S), is 0.75 or more and 5.5 or less; and component (B): an organic solvent having a hydroxy group.

Provided herein are free base crystalline forms, crystalline salts, and an amorphous salts of omecamtiv mecarbil.

The present invention relates to novel hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, Alzheimer's Disease, cancer, cardiovascular disease, diabetic nephropathy, diabetic retinopathy, a disorder of glucose metabolism, dyslipidemia, dyslipoproteinemia, hypertension, impotence, inflammation, insulin resistance, lipid elimination in bile, obesity, oxysterol elimination in bile, pancreatitis, pancreatitius, Parkinson's disease, a peroxisome proliferator activated receptor-associated disorder, phospholipid elimination in bile, renal disease, septicemia, metabolic syndrome disorders (e.g., Syndrome X), thrombotic disorder. Compounds and methods of the invention can also be used to modulate C reactive protein or enhance bile production in a patient. In certain embodiments, the compounds, compositions, and methods of the invention are useful in combination therapy with other therapeutics, such as hypocholesterolemic and hypoglycemic agents.

The present invention relates to novel hydroxyl compounds, compositions comprising hydroxyl compounds, and methods useful for treating and preventing a variety of diseases and conditions such as, but not limited to aging, Alzheimer's Disease, cancer, cardiovascular disease, diabetic nephropathy, diabetic retinopathy, a disorder of glucose metabolism, dyslipidemia, dyslipoproteinemia, hypertension, impotence, inflammation, insulin resistance, lipid elimination in bile, obesity, oxysterol elimination in bile, pancreatitis, pancreatitius, Parkinson's disease, a peroxisome proliferator activated receptor-associated disorder, phospholipid elimination in bile, renal disease, septicemia, metabolic syndrome disorders (e.g., Syndrome X), thrombotic disorder. Compounds and methods of the invention can also be used to modulate C reactive protein or enhance bile production in a patient. In certain embodiments, the compounds, compositions, and methods of the invention are useful in combination therapy with other therapeutics, such as hypocholesterolemic and hypoglycemic agents.