Absorbable implants for breast surgery that conform to the breast parenchyma and surrounding chest wall have been developed. These implants support newly lifted breast parenchyma, and/or a breast implant. The implants have mechanical properties sufficient to support a reconstructed breast, and allow the in-growth of tissue into the implant as it degrades. The implants have a strength retention profile allowing the support of the breast to be transitioned from the implant to regenerated host tissue, without significant loss of support. Three-dimensional implants for use in minimally invasive mastopexy/breast reconstruction procedures are also described, that confer shape to a patient's breast. These implants are self-reinforced, can be temporarily deformed, implanted in a suitably dissected tissue plane, and resume their preformed three-dimensional shape. The implants are preferably made from poly-4-hydroxybutyrate (P4HB) and copolymers thereof. The implants have suture pullout strengths that can resist the mechanical loads exerted on the reconstructed breast.

Absorbable implants for breast surgery that conform to the breast parenchyma and surrounding chest wall have been developed. These implants support newly lifted breast parenchyma, and/or a breast implant. The implants have mechanical properties sufficient to support a reconstructed breast, and allow the in-growth of tissue into the implant as it degrades. The implants have a strength retention profile allowing the support of the breast to be transitioned from the implant to regenerated host tissue, without significant loss of support. Three-dimensional implants for use in minimally invasive mastopexy/breast reconstruction procedures are also described, that confer shape to a patient's breast. These implants are self-reinforced, can be temporarily deformed, implanted in a suitably dissected tissue plane, and resume their preformed three-dimensional shape. The implants are preferably made from poly-4-hydroxybutyrate (P4HB) and copolymers thereof. The implants have suture pullout strengths that can resist the mechanical loads exerted on the reconstructed breast.

Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a silk fibroin component.

Hydrogels comprising a macromolecular matrix and water may be used to augment soft tissue of a human being, promote or support cell or tissue viability or proliferation, create space in tissue, and for other purposes. A macromolecular matrix may comprise a hyaluronic acid component crosslinked to a silk fibroin component.

The present disclosure relates to surgical grafts for replacing nipples and areolas lost to disease or trauma with surgical grafts of decellularized donor nipples and areolas and to placing and recellularizing such grafts. The disclosure further provides methods for decellularizing epidermis. The decellularized epidermis can be used as a protective cover for skin wounds.

The present disclosure relates to surgical grafts for replacing nipples and areolas lost to disease or trauma with surgical grafts of decellularized donor nipples and areolas and to placing and recellularizing such grafts. The disclosure further provides methods for decellularizing epidermis. The decellularized epidermis can be used as a protective cover for skin wounds.

A garment containing a pocket and loop to securely hold a single length of padding with bilateral breast mound prostheses for the mastectomy patient or other is disclosed. The garment includes a front layer, a middle section with a loop and a back layer. The single length of padding with bilateral breast mound prostheses is securely placed into the pocket and loop component of the garment. The garment is also able to take on various forms in order to securely hold two separate breast mound prostheses if desired.

A garment containing a pocket and loop to securely hold a single length of padding with bilateral breast mound prostheses for the mastectomy patient or other is disclosed. The garment includes a front layer, a middle section with a loop and a back layer. The single length of padding with bilateral breast mound prostheses is securely placed into the pocket and loop component of the garment. The garment is also able to take on various forms in order to securely hold two separate breast mound prostheses if desired.

The invention relates to a method for manufacturing a breast prosthesis, in which a first dispersion of a first granular material is introduced into a cross-linkable silicone compound. The silicone compound subsequently is cured in order to form a prosthesis body, wherein the prosthesis body is heated to a shrinking temperature which lies above the melting point of the thermoplastic material.

The invention relates to a method for manufacturing a breast prosthesis, in which a first dispersion of a first granular material is introduced into a cross-linkable silicone compound. The silicone compound subsequently is cured in order to form a prosthesis body, wherein the prosthesis body is heated to a shrinking temperature which lies above the melting point of the thermoplastic material.