The present invention relates to a compound having antibacterial properties suitable for use as an antibacterial monomer, a photopolymerizable composition which includes said compound, and use thereof in a dental procedure.

A drug containing, as an active ingredient, a compound having an antagonistic activity against an EP.sub.2 receptor in the prevention and/or treatment of a disease associated with the activation of an EP.sub.2 receptor, of formula (I-A):

##STR00001##

wherein all symbols have the same meanings as those described in the specification, or a pharmaceutically acceptable salt thereof.

A drug containing, as an active ingredient, a compound having an antagonistic activity against an EP.sub.2 receptor in the prevention and/or treatment of a disease associated with the activation of an EP.sub.2 receptor, of formula (I-A):

##STR00001##

wherein all symbols have the same meanings as those described in the specification, or a pharmaceutically acceptable salt thereof.

Provided is a degrader for injured mitochondria based on an autophagy mechanism, the degrader including a compound or a salt thereof, the compound containing a ligand capable of binding to or accumulating in mitochondria and a substituent represented by the following general formula (1): ##STR00001##
where R.sup.1, R.sup.2, and R.sup.3 are identical to or different from each other, and each represent a hydrogen atom or the like.

Provided is a degrader for injured mitochondria based on an autophagy mechanism, the degrader including a compound or a salt thereof, the compound containing a ligand capable of binding to or accumulating in mitochondria and a substituent represented by the following general formula (1): ##STR00001##
where R.sup.1, R.sup.2, and R.sup.3 are identical to or different from each other, and each represent a hydrogen atom or the like.

Provided herein, inter alia, are compound and methods of treating cancer by inhibiting HDAC8.

Provided herein, inter alia, are compound and methods of treating cancer by inhibiting HDAC8.

The present invention relates to activators of caspase-8/c-FLIP.sub.L dimerization and their use in enhancing the pro-apoptotic activity of the heterodimer and cancer therapy.

The present invention relates to activators of caspase-8/c-FLIP.sub.L dimerization and their use in enhancing the pro-apoptotic activity of the heterodimer and cancer therapy.

Disclosed herein is a compound of formula (I), or a pharmaceutically acceptable salt thereof. Also disclosed herein are uses of a compound disclosed herein in the potential treatment or prevention of an IDO-associated disease or disorder. Also disclosed herein are compositions comprising a compound disclosed herein. Further disclosed herein are uses of a composition in the potential treatment or prevention of an IDO-associated disease or disorder. ##STR00001##