C07D311/72

Synthesis of chromanol derivatives
11673874 · 2023-06-13 · ·

The present invention relates to a process for the production of chromanol derivatives, more specifically to a process for preparing a compound of the general formula I wherein R.sup.1, R.sup.2 and R.sup.3 independently of each other are selected from hydrogen and methyl, R.sup.4 is selected from C-.sub.1-C.sub.6-alkyl, and X is selected from C.sub.1-C.sub.20-alkyl and C.sub.2-C.sub.20-alkenyl. ##STR00001##

Synthesis of chromanol derivatives
11673874 · 2023-06-13 · ·

The present invention relates to a process for the production of chromanol derivatives, more specifically to a process for preparing a compound of the general formula I wherein R.sup.1, R.sup.2 and R.sup.3 independently of each other are selected from hydrogen and methyl, R.sup.4 is selected from C-.sub.1-C.sub.6-alkyl, and X is selected from C.sub.1-C.sub.20-alkyl and C.sub.2-C.sub.20-alkenyl. ##STR00001##

METHOD FOR THE PRODUCTION OF VITAMIN E WITH A HIGH PURITY, VITAMIN E PRODUCED BY SAID METHOD, AND A COMPOSITION COMPRISING SAID VITAMIN E

A method is provided for manufacturing high-purity vitamin E compounds by selectively separating vitamin E compounds such as tocotrienols and tocopherols from oil raw materials such as deodorized distillate, and more specifically, a method is provided, applying to a rich fraction of vitamin E compounds, for obtaining high-purity vitamin E compounds by separating and removing only free fatty acids contained as impurities. The method comprises a process in which a solution containing vitamin E compounds and free fatty acids is placed in contact with a weakly basic anion exchanger, and the free fatty acids are preferentially adsorbed.

METHOD FOR THE PRODUCTION OF VITAMIN E WITH A HIGH PURITY, VITAMIN E PRODUCED BY SAID METHOD, AND A COMPOSITION COMPRISING SAID VITAMIN E

A method is provided for manufacturing high-purity vitamin E compounds by selectively separating vitamin E compounds such as tocotrienols and tocopherols from oil raw materials such as deodorized distillate, and more specifically, a method is provided, applying to a rich fraction of vitamin E compounds, for obtaining high-purity vitamin E compounds by separating and removing only free fatty acids contained as impurities. The method comprises a process in which a solution containing vitamin E compounds and free fatty acids is placed in contact with a weakly basic anion exchanger, and the free fatty acids are preferentially adsorbed.

FORMULATIONS FOR THE DELIVERY OF ACTIVE AGENTS TO INSECTS, PLANTS, AND PLANT PATHOGENS

The present disclosure is directed to formulations comprising (1) at least one formulation transport agent, (2) at least one complexing agent, and (3) at least one active agent that modulates one or more traits of a target insect, plant, or plant pathogen. The present disclosure is also directed to methods of delivering such formulations to the target organism, as well as to formulation transport agents used to prepare such formulations.

LONG-CHAIN CARBOXYCHROMANOLS AND ANALOGS FOR USE AS ANTI-INFLAMMATORY AGENTS
20170296505 · 2017-10-19 · ·

Long-chain carboxychromanol compounds useful for treating conditions associated with the need to inhibit cyclooxygenase-1, cyclooxygenase-2, and/or 5-lipoxygenase, and pharmaceutical formulations containing the compounds are provided herein.

METHODS FOR ENRICHING ALPHA-TOCOTRIENOL FROM MIXED TOCOL COMPOSITIONS

Provided herein are methods for making an alpha-tocotrienol enriched tocol mixture, such as from a plant or plant-derived material. Also provided herein are simulated moving bed purification methods for tocotrienol compounds such as alpha tocotrienol.

METHODS FOR ENRICHING ALPHA-TOCOTRIENOL FROM MIXED TOCOL COMPOSITIONS

Provided herein are methods for making an alpha-tocotrienol enriched tocol mixture, such as from a plant or plant-derived material. Also provided herein are simulated moving bed purification methods for tocotrienol compounds such as alpha tocotrienol.

ALPHA-TOCOPHEROL-BASED ADJUVANTED SOLVENT FOR DNA VACCINES
20170246295 · 2017-08-31 ·

The present invention discloses a delivery system for nucleic acid vaccines comprising an emulsion of tocol and esters hereof. Vaccines and new ways of administration of DNA vaccines are disclosed.

LEATHER OR LEATHER ARTICLE AND METHOD FOR PRODUCING SAME, HEXAVALENT CHROMIUM TREATMENT AGENT, METHOD FOR TREATING HEXAVALENT CHROMIUM IN CRUDE LEATHER OR CRUDE LEATHER ARTICLE
20170233835 · 2017-08-17 · ·

An object of the invention is to provide a heat-resistant hexavalent chromium removal agent, which is capable of remaining in a leather or leather article for a long period of time and stably detoxifying hexavalent chromium over the long term even when a leather or leather article contains hexavalent chromium, and a leather or leather article, in which the hexavalent chromium content is less than 3 ppm. The leather or leather article of the present invention contains at least: an organic compound (A) having a structure shown in chemical formula (1) and hydroxyphenyl but not aldehyde and carboxyl, which organic compound has a property to reduce hexavalent chromium to trivalent chromium; and trivalent chromium, and the hexavalent chromium content determined in accordance with ISO 17075: 2008-02 is less than 3 ppm.