Patent classifications
C07D311/84
Hydrazinyl and aminooxy compounds and their methods of use
The present disclosure is directed dye compounds containing a hydrazinyl substituent and optionally, one or more negatively charged groups, such as sulfonate, phosphate, phosphonate, and/or carboxylate groups and dye compounds containing an aminooxy substitutent. The compounds are useful in the detection of analytes containing aldehyde and ketone groups, including, for example, glycans.
HYDRAZINYL AND AMINOOXY COMPOUNDS AND THEIR METHODS OF USE
The present disclosure is directed dye compounds containing a hydrazinyl substituent and optionally, one or more negatively charged groups, such as sulfonate, phosphate, phosphonate, and/or carboxylate groups and dye compounds containing an aminooxy substitutent. The compounds are useful in the detection of analytes containing aldehyde and ketone groups, including, for example, glycans.
HYDRAZINYL AND AMINOOXY COMPOUNDS AND THEIR METHODS OF USE
The present disclosure is directed dye compounds containing a hydrazinyl substituent and optionally, one or more negatively charged groups, such as sulfonate, phosphate, phosphonate, and/or carboxylate groups and dye compounds containing an aminooxy substitutent. The compounds are useful in the detection of analytes containing aldehyde and ketone groups, including, for example, glycans.
OPTIMIZED CHIMERIC RECEPTOR T CELL SWITCHES AND USES THEREOF
Disclosed herein are switches for regulating the activity of a chimeric antigen receptor effector cells (CAR-ECs). The switches generally comprise a chimeric antigen receptor-interacting domain (CAR-ID) and a target interacting domain (TID). The switch may further comprise a linker. Further disclosed herein are methods of using the switches for the treatment of one or more conditions or diseases in a subject in need thereof.
OPTIMIZED CHIMERIC RECEPTOR T CELL SWITCHES AND USES THEREOF
Disclosed herein are switches for regulating the activity of a chimeric antigen receptor effector cells (CAR-ECs). The switches generally comprise a chimeric antigen receptor-interacting domain (CAR-ID) and a target interacting domain (TID). The switch may further comprise a linker. Further disclosed herein are methods of using the switches for the treatment of one or more conditions or diseases in a subject in need thereof.
Leveling composition and method for electrodeposition of metals in microelectronics
The present disclosure relates to a leveling composition for electrodepositing metals. The composition comprises a compound of formula (I): ##STR00001##
Leveling composition and method for electrodeposition of metals in microelectronics
The present disclosure relates to a leveling composition for electrodepositing metals. The composition comprises a compound of formula (I): ##STR00001##
Method for producing peptide compound, protective group-forming reagent, and condensed polycyclic compound
Provided are a method for producing a peptide compound including a step of using a compound represented by Formula (1); a protective group-forming reagent including the compound; and the compound. At least one of R.sup.1 to R.sup.8 or Y.sup.2 has R.sup.A, R.sup.A represents an aliphatic hydrocarbon group or an organic group having an aliphatic hydrocarbon group, and the number of carbon atoms in at least one aliphatic hydrocarbon group is 12 or more. However, R.sup.A does not have a silyl group and a hydrocarbon group having a silyloxy structure. ##STR00001##
Catalyst system, olefin polymerization catalyst components comprising at least an internal electron donor compound, and methods of making and using the same
An olefin polymerization catalyst component comprising an internal electron donor compound shown in formula (I) below is provided in this disclosure: ##STR00001##
wherein X is O, S, NR.sup.a, PR.sup.b, or POOR.sup.c, R.sup.a is independently hydrogen, halogen, carbonyl hydrocarbon, linear or branched unsaturated or saturated alkyl hydrocarbon, cyclic, aromatic, or aliphatic hydrocarbon, R.sup.b is independently hydrogen, halogen, carbonyl hydrocarbon, linear or branched unsaturated or saturated alkyl hydrocarbon, linear or branched unsaturated or saturated alkoxy hydrocarbon, cyclic, aromatic, or aliphatic hydrocarbon, R.sup.c is independently hydrogen, carbonyl hydrocarbon, linear or branched unsaturated or saturated alkyl hydrocarbon, cyclic, aromatic, or aliphatic hydrocarbon, R1-R8 are identical or different hydrogen, halogen, linear or branched unsaturated or saturated C.sub.1-C.sub.30 alkyl, alone or in combination with C.sub.5-C.sub.30 substituted or unsubstituted 5-or 6-membered aliphatic or aromatic hydrocarbon rings, each of R.sup.a, R.sup.b, R.sup.c, and/or R1-R8 are optionally substituted with halogen.
Catalyst system, olefin polymerization catalyst components comprising at least an internal electron donor compound, and methods of making and using the same
An olefin polymerization catalyst component comprising an internal electron donor compound shown in formula (I) below is provided in this disclosure: ##STR00001##
wherein X is O, S, NR.sup.a, PR.sup.b, or POOR.sup.c, R.sup.a is independently hydrogen, halogen, carbonyl hydrocarbon, linear or branched unsaturated or saturated alkyl hydrocarbon, cyclic, aromatic, or aliphatic hydrocarbon, R.sup.b is independently hydrogen, halogen, carbonyl hydrocarbon, linear or branched unsaturated or saturated alkyl hydrocarbon, linear or branched unsaturated or saturated alkoxy hydrocarbon, cyclic, aromatic, or aliphatic hydrocarbon, R.sup.c is independently hydrogen, carbonyl hydrocarbon, linear or branched unsaturated or saturated alkyl hydrocarbon, cyclic, aromatic, or aliphatic hydrocarbon, R1-R8 are identical or different hydrogen, halogen, linear or branched unsaturated or saturated C.sub.1-C.sub.30 alkyl, alone or in combination with C.sub.5-C.sub.30 substituted or unsubstituted 5-or 6-membered aliphatic or aromatic hydrocarbon rings, each of R.sup.a, R.sup.b, R.sup.c, and/or R1-R8 are optionally substituted with halogen.