An intra-oral device extending between a proximal end closer to a patient's mouth and a distal end closer to a bottom of the upper airway, includes a base member configured and arranged to be secured to at least one tooth, a crossbrace coupled to the base member, and a conduit coupled to at least one of the base member and the crossbrace, the conduit spanning the base member and extending to a distance equal to or past an end of the base member adjacent the proximal end.

A method of manufacturing an intraoral device (1) including: obtaining an impression of at least one row of a patient's teeth; transferring said impression into a processor; said processor communicating with a milling machine; milling a blank of a first material to form a cavity in said blank substantially corresponding to said impression, said cavity being milled to include an offset; said cavity with at least a second material and allowing said second material to cure; milling said second material to correspond to said impression; milling said first material to obtain a device shape; cleaning said device (1); and wherein said first and second materials are comparatively hard and soft.

Provided is a mandibular advancement system including: an upper teeth seating part on which upper teeth of a user is placed; a lower teeth seating part on which lower teeth of the user is placed; a driver connected to the upper teeth seating part and the lower teeth seating part and configured to change a relative location of the lower teeth seating part with respect to the upper teeth seating part; a detector configured to detect biometric information of the user; and a controller configured to control driving of the driver based on the biometric information provided by the detector, wherein the driver is disposed outside an oral cavity of the user.

The present disclosure provides generally for a therapeutic oral device for sleep apnea and associated methods for using the device. According to the present disclosure, the device may comprise a hard palate portion, mouth guard portion, and a tongue retainer portion. The hard palate portion may comprise one or more materials. The hard palate portion may also comprise a composite of materials, including but not limited to embedded materials. The mouth guard portion may comprise one or more components that provide stability and maintain the position of the therapeutic oral device within the mouth. The tongue retainer portion may comprise an airway and a predetermined length. A method of use may comprise the utilization of one or more incremental oral devices to overcome a gag reflex. When the oral device is formed from a mold, the mouth guard portion and the hard palate portion may be custom fit to the dimensions of the intended mouth.

Systems, methods, devices, and apparatus for positioning a patient's mandible in response to sleep apnea status are provided herein. In one aspect, a system for monitoring and treating sleep apnea in a patient comprises one or more sensors configured to monitor the patient for symptoms associated with sleep apnea; an intraoral appliance worn by the patient, one or more processors, and memory comprising instructions executable by the one or more processors to cause the one or more processors to: receive a set of sensor data from the one or more sensors, detect, using a machine learning algorithm, onset of a sleep apnea event based on the set of sensor data, and transmit a control signal to the intraoral appliance to cause the intraoral appliance to displace a lower jaw of the patient from a first position to a second position in order to treat the sleep apnea event.

Disclosed herein are mandibular advancement devices comprising an upper splint and a lower splint, where the upper splint comprises one or more upper fins, where each upper fin is located at a distance UD from back of the upper splint; the lower splints comprise one or more lower fins, where each lower fin is located at a distance LD from back of the lower splint; where the position of the upper and lower fins is unchangeable. Also disclosed are methods of reducing partial constriction of airway during sleep for a patient, the method comprising identifying a patient in need thereof; and administering to the patient the disclosed mandibular advancement device. Also disclosed are methods of manufacturing a mandibular advancement device, the method comprising obtaining measurements from a patient's dentition; digitally designing a mandibular advancement device; and milling the mandibular advancement device.

Example resource management systems and methods are described. In one implementation, a resource manager is configured to manage data processing tasks associated with multiple data elements. An execution platform is coupled to the resource manager and includes multiple execution nodes configured to store data retrieved from multiple remote storage devices. Each execution node includes a cache and a processor, where the cache and processor are independent of the remote storage devices. A metadata manager is configured to access metadata associated with at least a portion of the multiple data elements.

An intra-oral device comprising upper and lower jaw applicators, the upper jaw applicator comprising upper left and upper right components, and the lower jaw applicator comprising lower left and lower right components; a transverse adjustment mechanism for simultaneously adjusting a distance between the upper left and upper right components, and the lower left and lower right components wherein the transverse adjustment mechanism comprises: a threaded rod having one end portion engageable with the upper left and lower left components, and another end portion engageable with the upper right and the lower right components.

A system for treating obstructive sleep apnea (OSA) is described. The system may include a locking device having a size and shape selected to couple to skin along a jaw of a patient. The locking device may be configured to receive at least one of a needle or an introducer for insertion into a tongue of the patient for lead placement of a lead for OSA treatment, and lock at least a portion of the at least one of the needle or introducer in place to reduce movement of the needle or introducer within the tongue.

An oral appliance for the treatment of obstructive sleep apnea includes a mouthpiece configured for being received in an oral cavity of a user. The mouthpiece may include a pulse oximeter, a pressure sensor, an airflow sensor, an actigraphy sensor, a noise detector, and at least one stimulator for providing stimulation to a user's tongue in the event of decreased oxygen saturation levels, increased pressure applied to occlusal surfaces of the user's dentition, decreased actual airflow levels and/or increased noise levels. A microprocessor receives data from the oxygen sensor, pressure sensor, airflow sensor, actigraphy sensor and noise detector, and activates the at least one stimulator.