A method and system of reducing the likelihood of a Porphyromonas gingivalis infection in a human being includes the use of a bioadhesive strip that binds to a person's mucosal membrane for at least 1 hour while inside a person's mouth, where the strip has a therapeutically effective amount of an anti-biofilm agent, compounds that facilitate the growth of desired bacteria beneficial to a person's health, and an antibiotic effective amount to kill Porphyromonas gingivalis bacteria. The method and system reduces the virulence factor gingipain. In other embodiments, the likelihood that a subject will suffer from Alzheimer's Disease is reduced by administering, via local gingival application to a subject that has been diagnosed with periodontitis, an effective amount of an antibiotic effective to kill Porphyromonas gingivalis bacteria residing on the subgingival tooth area of the subject.

A customizable mandibular advancement device for use in treating snoring and obstructive sleep apnea is provided. The device comprises upper and lower trays adapted to be fitted to a person's maxillary and mandibular arches. The upper tray comprises a stop member, which when engaged with a fin located on the lower tray, inhibits the posterior movement of the user's mandible thereby maintaining the mandible in an advanced position. Both the upper and lower trays comprise a core that is overmolded by a thermoplastic material that has a much lower softening temperature than the core.

A mandibular positioning facial retrognathism orthodontic system and a design method thereof are disclosed. The orthodontic system includes a maxillary shell-like dental appliance having a shell-like body, a protrusion portion protruding toward an opposite jaw is disposed at a posterior area corresponding to the shell-like body, a traction portion is disposed at a labial side of the shell-like body, and a retaining portion configured for fastening with a retaining attachment is disposed at the posterior area corresponding to the shell-like body. The protrusion portion is engaged with the posterior area of a mandibular for occlusal reconstruction, so that mandibular incisors are aligned with maxillary incisors. The design method is a design method for the mandibular positioning facial retrognathism orthodontic system, which can provide a treatment-specific orthodontic system, thereby achieving treatment of mandibular positioning facial retrognathism.

A mouth guard includes a tray configured to encompass at least anterior teeth of a dental arch. The tray includes a pair of protrusions extending away from the tray, each protrusion configured to generally overlie a canine of the dental arch. The protrusions are configured to engage one or more anterior teeth of a dental arch, whereby damage to the at least anterior teeth of the dental arch is reduced or prevented.

A device including one or more preformed or customized eruption guidance appliances placed in an individual's mouth. The preformed appliances are vibrated with a pulsation device to encourage tooth eruption by increasing the force and efficiency of the eruption toward a preferred location and a preferred alignment as well as providing increased blood flow and blood oxygen flow to the muscles and tissues in and around the oral cavity of the individual. The preformed guidance appliance driven by the pulsation device is selected from a range of guidance appliances, each of which is selected by size and shape to fit an individual based on the individuals anticipated tooth and jaw size as well as the growth profile. The pulsation can increase the blood and oxygen flow to the many muscles that surround the appliances outside surfaces that can alter mouth breathing, prevent impingement of the oropharynx from the abnormal distalization of the tongue and mandible during sleep, the proper resting posture of the tongue, increased nasal breathing, prevent snoring, improve abnormal swallowing, correct thumb sucking and various abnormalities of speech.

A medical appliance for the treatment of obstructive sleep apnea in a patient, the appliance comprising: a securing device configured to be removably affixed to the patient's jaw; and a biasing member which is insertable behind the soft palate and/or the base of the patient's tongue, thereby providing for the flow of air in the nasopharyngeal airway; wherein the securing device is connected to the biasing member to allow insertion and/or removal of the biasing member from the nasopharyngeal airway.

A dental appliance to reduce or eliminate snoring is disclosed. The dental appliance includes an upper tray, a lower tray, one or more tray-removal features, and a connecting arm. The upper tray includes a first coupling post located on a buccal surface of the upper tray. The lower tray includes a second coupling post located on a buccal surface of the lower tray. Each of the coupling posts includes a flange configured to pivotably and slidably secure the connecting arm and to release the connecting arm when the upper tray is rotated to a predetermined angle with respect to a closed position of the upper and lower trays. The one or more tray-removal features are disposed on the buccal or lingual surface of each of the upper and lower trays.

Systems, devices and methods are disclosed for reshaping airways concurrently with dental and/or orthodontic treatment. The systems can have a series of two or more oral appliances configured to progressively reposition the maxillary and mandibular teeth in two or more successive steps. Each oral appliance in the series can have one or more maxillary blocks, one or more mandibular blocks, a maxillary oral tray, and a mandibular oral tray. One or more maxillary blocks can be attached to or integrated with the maxillary oral tray. One or more mandibular blocks can be attached to or integrated with the mandibular oral tray. The maxillary and mandibular oral trays can be configured to move one or more teeth from a tooth first position to a tooth second position. The maxillary and mandibular blocks can be configured to interact with one another to treat sleep breathing disorders.

A device and method for managing obstructive sleep apnea in patients. The device includes a first implantable member and a second implantable member, both configured to generate a magnetic field. The first implantable member is implanted in a base of a tongue and the second implantable member is implanted in a soft palate such that like magnetic poles of the first implantable member and the second implantable member face each other resulting in repulsion between the first implantable member and the second implantable member. The repulsive force between the first implantable member and the second implantable member can open the respiratory airway and keep it open.

An appliance and methods are described that include embodiments of a mandibular advancement or positioning device which can use elastic bands to pull the jaw forward. The appliance has an upper plastic tray conforming to the patient's upper teeth and including 3D printed sets of retention hooks coupled to the upper plastic tray via being encased in plastic, one on the right and one on the left anterior buccal portion of an upper plastic base. The appliance also has a lower plastic tray conforming to the patient's lower teeth including mandibular dentition, and includes having a 3D printed bite pad which opens the bite vertically. The lower tray also has a set of 3D printed plastic retention hooks encased in plastic extending outwardly from the teeth, one on the right and one on the left of the posterior buccal portion of the lower plastic base. Elastic bands of different lengths and strengths are attached to both the top and bottom retention hooks on both sides of the trays to pull the mandible forward for treatment.