Compositions consisting of block copolymers ,-di-aryl or alkyl sulfonates of poly(ethylene oxide).sub.w-poly(propylene oxide)-poly(ethylene oxide).sub.w of bis-ammonium and block copolymers ,-di-amine of poly(ethylene oxide).sub.w-poly(propylene oxide)-poly(ethylene oxide).sub.w, are provided that are effective in the dewatering and desalting crude oils whose specific gravities are within the range of 14 to 20 API. A method of dewatering and desalting heavy crude oil adds a mixture of the copolymer bifunctionalized with an aliphatic or aromatic secondary amine and a copolymer bifunctionalized with an aliphatic or aromatic tertiary amine.

Methods and compositions are described for enhancing tissue regeneration or wound repair in a mammalian subject comprising a composition comprising (a) a proline hydroxylase inhibitor component or molecule that increases or upregulates HIF1a and (b) a carrier component comprising a hydrogel.

The present invention relates to highly concentrated, anhydrous amine salts of hydrocarbon polyalkoxy sulfates, wherein the salts are selected from the group of substituted amines, preferably alkanolamines. The products obtained are of low viscosity and pumpable at room temperature. Due to the absence of water, the salts are highly resistant to hydrolysis, even at high temperatures. The invention further relates to the use of the compositions according to the invention in an aqueous dilution for use in oil reservoirs with the aim of achieving enhanced oil production, or for the recovery of hydrocarbons from tar sands or other surfaces or materials provided with hydrocarbon.

An antistatic agent for an ABS resin includes an ionically bonded salt ##STR00001##
where R.sub.1 is a substituted or unsubstituted straight, branched or cyclic C.sub.1 to C.sub.30 alkyl group, a substituted or unsubstituted C.sub.6 to C.sub.30 aryl group.sub.+ or a substituted or unsubstituted C.sub.7 to C.sub.30 arylalkyl group, A is a straight or branched C.sub.2 to C.sub.4 alkylene group, n is an integer from 0 to 50, and Q.sub.1 is a secondary or tertiary ammonium ion, or ##STR00002##
where R.sub.2 is a substituted or unsubstituted straight, branched or cyclic C.sub.1 to C.sub.30 alkyl group, a substituted or unsubstituted C.sub.6 to C.sub.30 aryl group, or a substituted or unsubstituted C.sub.7 to C.sub.31 arylalkyl group, A is a straight or branched C.sub.2 to C.sub.4 alkylene group, and Q.sub.2 is a secondary or tertiary ammonium ion.

Disclosed are ethylenically unsaturated salts of allyl (poly)ether sulfates utilized as reactive surfactants (emulsifiers) during emulsion polymerization.

Methods and compositions are described for enhancing tissue regeneration or wound repair in a mammalian subject comprising a composition comprising (a) a proline hydroxylase inhibitor component or molecule that increases or upregulates HIF1a and (b) a carrier component comprising a hydrogel.

An antimicrobial composition for the treatment of drug-resistant pathogens is provided. The composition includes antimicrobial compounds and chelating agents assemblies that are particularly effective in inhibiting drug-resistant bacteria and biofilm growth. Optionally, the composition may include an efflux pump inhibitor, further enhancing activity against resistant bacteria. Also provided are methods of treating diseases and surfaces of materials treated with the composition.

A pharmaceutical composition for the treatment of pathological calculus and plaque formation is provided. The composition includes conjugates of polymers and metal binding agents that are particularly effective in inhibiting crystal nucleation, growth, and aggregation in the body, such as that observed in the formation of kidney stones. The composition is effective at low dosage, thereby avoiding the side effects typically associated with current treatments for kidney stones. The composition is also effective against plaque formation, and may have intrinsic antimicrobial activity. Also provided are methods of treating diseases and surfaces of devices and materials treated with the composition.

The present invention relates to methods, compositions, and kits for generating conjugated gold nanoparticles. In certain embodiments, the present invention provides methods of generating unsaturated conjugated gold nanoparticles by mixing naked gold nanoparticles with a first type of attachment molecules at a molar ratio such that the attachment molecules attach to the naked gold particles at a density level below the saturation level of the naked gold particles (e.g., at a saturation level of 1-99%). In some embodiments, a second type of attachment molecules (e.g., with the opposite charge as the first type of attachment molecules) are mixed with the unsaturated conjugated gold nanoparticles to generate double-conjugated gold nanoparticles (e.g., that are zwitterionic).

The present disclosure provides compositions comprising mannose-fused antigens to target mannose receptors. The compositions may be used to prevent immunity or reduce an immune response protein-based drugs that would otherwise elicit an immune response.