Devices for therapeutic interaction with an Abreu brain thermal tunnel (ABTT) terminus. Such devices provide heat to or remove heat from the ABTT terminus, and may also provide heat to or remove heat from veins connected to the ABTT. Therapeutic devices for engaging with the ABTT terminus benefit from diagnostics obtained at the ABTT terminus, or from other locations on the body.

A container including an opening in a top portion sized and adapted to receive water from a water source; one or more side walls and a bottom wall below the opening, the one or more side walls and the bottom wall forming at least one interior compartment; a plurality of apertures on the bottom wall; and one or more fasteners in the top portion above the opening, the one or more fasteners being adapted to attach the container to the water source, wherein the one or more side walls incorporate an insulating material and the at least one interior compartment is thereby adapted to contain a cooling substance for cooling the water received from the water source and to allow cooled water to exit the at least one interior compartment through the plurality of apertures on the bottom wall.

Proposed are a method of providing a frozen composition and a device therefor and, more specifically, to a method of spraying a composition in a frozen state to a target region and a device therefor. A composition in a liquid state may be sprayed together with a refrigerant, and the composition may be frozen into a solid state by the refrigerant having a relatively low temperature and may reach the target region. The composition in a solid state may have the effect of improving skin penetration compared to the composition in a liquid state.

Proposed is a method of rapidly and precisely cooling a skin area of a subject in combination with a treatment of the skin area. The method may include providing a handheld cooling device. The device may include an applicator tip, and a controlled cryogen spray element configured to spray controlled cryogen. The method may also include contacting the tip on the skin area, spraying the controlled cryogen onto the skin area, and applying the treatment to the skin area.

Proposed is a hand-held cooling device for supplying a cryogen to a target region for cryotherapy. The device can include a cryogen container configured to contain a first cryogen having a first temperature and a nozzle configured to spray a first modified cryogen to the target region, the first modified cryogen having a second temperature higher than the first temperature. The device can also include a cryogen temperature regulator configured to receive the first cryogen and output the first modified cryogen to the nozzle, the cryogen temperature regulator disposed closer to the nozzle than the cryogen container. The cryogen temperature regulator can include a holder tube, a porous structure disposed inside a holder tube and a heater disposed around the holder tube and heating the holder tube so as to increase the first temperature to the second temperature while the first cryogen passes through the porous structure.

A dual-channel spike includes a shaft having inlet and outlet openings defined therein, a pointed distal end, and a proximal end, the shaft extending along an axis between the proximal end and the pointed distal end, the pointed distal end configured to puncture an intravenous fluid bag; a handle attached to the proximal end of the shaft; an inlet connector fluidly coupled to the handle, the inlet connector configured to be fluidly connected to a first fluid line; an outlet connector fluidly coupled to the handle, the outlet connector configured to be fluidly connected to a second fluid line; an inlet channel defined in the shaft and the handle, the inlet channel fluidly coupling the inlet connector and the outlet opening; and an outlet channel defined in the shaft and the handle, the outlet channel fluidly coupling the outlet connector and the inlet opening.

Embodiments include a cryogenic device for alleviating pain by cryogenically treating a nerve, the cryogenic device including a handpiece; a needle coupled to a distal end of the handpiece, the needle including a needle lumen, the needle being configured for insertion into a skin of a patient along an insertion axis at a site laterally displaced from a treatment zone proximate to the nerve. The needle is configured to resiliently bend after insertion away from the insertion axis, such that at least a portion of the needle is adapted to traverse a skin layer laterally toward the treatment zone. The device includes a cooling fluid supply tube extending distally into the needle lumen; and a cooling fluid source, wherein the cooling fluid source is coupled to the cooling fluid supply tube to direct cooling fluid into the needle lumen.

A temperature control system includes a nasal cannula. The nasal cannula includes a first elongated prong having a first axial fluid channel and an aperture, providing access to the first axial fluid channel, on a side wall of the first elongated prong. The nasal cannula further includes a second elongated prong having a temperature sensor associated with a distal portion thereof and a fluid supply configured to direct fluid through the first axial fluid channel of the first elongated prong and out of the first aperture to a target area. The nasal cannula further includes control circuitry configured to receive one or more signals from the temperature sensor and modify one or more properties of the fluid in response to the one or more signals from the temperature sensor.

A method for controlling tissue temperature involves providing a nasal cannula including a first elongated prong with an axial fluid channel and a downwardly-curved shape. The nasal cannula further includes a first aperture on a side wall of a distal portion of the first elongated prong. The first aperture provides access to the axial fluid channel. The method includes inserting the first elongated prong into a nasal cavity of a subject to face the first aperture at a pharyngeal wall of the subject and modifying a temperature of the pharyngeal wall by delivering a first fluid portion through the axial fluid channel and out of the first aperture to the pharyngeal wall.

A biological parameter monitoring system is provided that includes a medical monitoring device that measures and generates a biological signal representative blood pressure, eye pressure, heart rate, temperature, oxygen, blood gas, chemical compounds, drugs, analytes, glucose, oxygen saturation, or blood components. The system also includes a household appliance that communicates with the medical monitoring device, and includes a display that displays customary information and an indicator representative of the signal generated by the medical monitoring device.