A closed loop catheter useable for heat exchange is manufactured by forming a plurality of generally transverse bore holes though a flexible, multilumen catheter body, lacing a tube trough the bore holes so that loops of the tube protrude from the catheter body, connecting one end of the tube to an inflow lumen of the catheter and connecting the other end of the tube to an outflow lumen of the catheter. A heated or cooled heat exchange medium may then be circulated through the tube while the catheter is inserted in the vasculature of a subject, thereby resulting in heat exchange between the subject's flowing blood and the heat exchange medium being circulated through the tube.

A temperature controlled cosmetic treatment facial mask with area-specific treatments of the present invention includes a substantially planar mask body which is formed with cut-outs for a person's eyes, nose, and mouth. The mask may include a number of large and small area treatment zones in combination with asymmetrical treatment zones suitable for treatment of specific and localized skin conditions. The treatments zones are coated with skin treatments, such as compounds, lotions, gels, and the like as are known in the facial treatment, cosmetics, spa and medical industry. The mask may include a self-heating or cooling substrate to provide temperature control to the face mask and each mask may include heating areas, cooling areas, or both. A system is also provided that includes an imaging device that feeds its output to a central computer system having an image analyzer, CPU, memory and Look Up Table, and face map for determining specific treatment requirements for the particular patient. An output from the central computer system is provided to a treatment deposition device which deposits various treatments onto an intermediate membrane layer to generate a custom temperature controlled facial mask with area-specific treatments for that particular patient.

The present invention relates to a device (1) for the administration of a cosmetic product, with a first holder (2) for a pressurized gas cartridge (3), a second holder (4) for a cosmetic product container (5), flow rate regulating means (6), a nozzle (7) with heating means (8), and a trigger (9) which allows opening the passage of gas when operated. The first holder (2) allows housing a cartridge (3) for the passage of pressurized gas towards the flow rate regulating means (6). The first holder (2), the flow rate regulating means (6) and the nozzle (7) are fluidically connected. The regulating means are located downstream of the first holder (2) and upstream of the nozzle (7). The second holder (4) allows housing a container (5) for the passage of a product towards the nozzle (7) by means of a first conduit (10). The invention also relates to the corresponding process, use and container.

A dry eye treatment device is provided having a mask defining a treatment cavity which is positionable on a face of a user over the eyes. A temperature altering pack such as a gel pack is positionable within the treatment cavity and a fabric cover may surround the gel pack and have medication absorbed or placed upon the fabric material.

An electrically-heatable plaster that comprises a self-adhesive skin contact layer, an electrically-conductive textile fabric in which electrically-conductive fibres are in contact with one another, as a heating element, and optionally at least one active substance, as well as to a method for production and the use of same for local heat therapy and/or transdermal application of active substances.

A steam-generative warming device 10 having a steam generating element 30 that releases steam in association with heat generation accompanying the oxidation of an oxidizable metal. The steam generative warming device 10 contains a capsaicin analog and a menthol in a capsaicin analog/menthol mass ratio of 1/300 to 1/20000. It is preferred that the capsaicin analog be present in an element adapted to be brought into direct contact with the user's skin and the menthol be present in an element adapted not to be brought into contact with the user's skin.

The invention provides a device for application to the skin of a patient to facilitate intravenous access, e.g. via needles, syringes, cannulas or catheters, the device having an upper surface and a lower surface, wherein the lower surface is suitable for contacting the skin of the patient at the location of a vein to be accessed. The device comprises a heat patch, an organic nitrate vasodilator agent and an amino based anaesthetic agent which is an amino ester or amino amide. The device is configured and arranged such that in use the device can be activated by the application of pressure to the patch so as to initiate an exothermic chemical reaction in the heat patch which heats the patch to a temperature of from 50 to 55 degrees Celsius for a period of time of one minute or more. Further, the device is configured and arranged such that when the device is applied to the skin of the patient, with the lower surface contacting the skin of the patient, the vasodilator agent and the anaesthetic agent are released from the lower side of the device onto the patient's skin at the location of a vein to be accessed.

Methods of treating a wart are provided which include: providing a heating device having a central zone and peripheral zone, sized to cover the wart and skin peripheral to the wart, and including a heat-generating material that undergoes an exothermic reaction when exposed to oxygen; providing a liquid therapeutic adhesive comprising a volatile solvent, skin-compatible adhesive and therapeutic agent; applying the liquid therapeutic adhesive to the skin peripheral to the wart or to the peripheral zone of the heating device; initiating the exothermic reaction of the heat-generating material by exposure of the heat-generating material to oxygen; applying the central zone of the heating device to contact the wart, thereby heating the wart and skin peripheral to the wart to an elevated skin temperature; and maintaining the elevated skin temperature for a period of time, thereby creating an enclosed heated environment treating the wart and skin peripheral to the wart.

A soft thermoformable elastomer with a phase change material exhibiting high latent heat of fusion. The compound provides elasticity, softness, formability, and heat over an extended duration and to facilitate prolonged skin contact at elevated temperatures. Used in combination with active ingredients the increased temperature and formability provides enhanced transdermal delivery through the skin. Thermoplastic elastomers may be manufactured by mixing together plasticizing oil, a triblock copolymer, a paraffinic substance and one or more additives, e.g., an antioxidant, an antimicrobial agent, and/or other additives to form a mixture which melted then cooled into the thermoplastic elastomer. During cooling, the thermoplastic elastomer may be molded or otherwise formed into any number of articles including, but not limited to, prosthetic liners, prosthetic sleeves, external breast prostheses, breast enhancement bladders, masks, wound dressing sheets, wound dressing pads, socks, gloves, malleolus pads, metatarsal pads, shoe insoles, urinary catheters, vascular catheters, and balloons for medical catheters both vascular as well as urinary. Active ingredients are preferably added to the cooling thermoplastic elastomer when the temperature is below 100 F. to prevent heat degradation and/or breakdown of vital proteins.

A medical bandage is provided, capable of being rapidly, adjustably, intuitively and universally fitted on a head, limb or stump, for instance to conceal and protect a wound. The medical bandage is cap-shaped, and is formed of several layers, and comprised at least one port for obtaining quick access to a wound concealed by the medical bandage. When open, a port can stabilize a drainage tube, or provide a passage through which to easily and rapidly apply a medicine. The medical bandage can be directly fit on the head or other body part, providing an all-in-one dressing, wrap and treatment, and eliminating the need for cumbersome and difficult to manage gauze roll and multiple bandages of various sizes, shapes, and uses. The medical bandage provides simple, rapid, and effective treatment of emergency trauma wounds, and improved medical treatment of acute or chronic wounds.