Neuromodulation catheter systems with controlled irrigation capabilities and methods for using such systems are disclosed herein. One such method includes, for example, positioning an irrigated neuromodulation catheter at a treatment site within a renal blood vessel of a human patient, delivering neuromodulation energy at the treatment site, and delivering irrigation fluid to the treatment site having characteristics coordinated with the delivered energy. The characteristics can be adjusted to maintain an energy delivery element and/or tissue of the blood vessel at a constant temperature as power is increased. The method can further include monitoring at least one parameter of the tissue and/or of the energy delivery element, and adjusting the neuromodulation energy and/or the characteristics of the irrigation fluid if the at least one parameter falls outside of a treatment range of values.

Devices, systems and methods for controlling the temperature of all or part of the body of a human or animal subject.

Relatively non-invasive devices and methods for heating or cooling a patient's body are disclosed. Devices and methods for treating ischemic conditions by inducing therapeutic hypothermia are disclosed. Devices and methods for inducing therapeutic hypothermia through esophageal cooling are disclosed. Devices and methods for operative temperature management are disclosed.

A device for cooling locally, including a cooling member, a crystal having the capacity to cool via absorption of a near-infrared exciting light signal, an illuminating system intended to deliver an exciting light signal, the crystal having an elongate shape about a longitudinal axis between a near end and a far end and having a closed constant outside cross section and containing a central channel formed, from its far end, over at least some of its length, the cooling member including a rod embedded via a first end into the central channel of the crystal and including a protruding second end that forms a cooling finger.

An endorectal cooling device (ECD) includes an elongated body, a cooling fluid circuit, and a gas bubble removal device. The elongated body includes an insertable portion for insertion into a patient's rectum and an external portion that remains external to the rectum. The cooling fluid circuit is defined in the elongated body from the external portion to the insertable portion and circulates cooling fluid to regulate a temperature of a cooling surface on the insertable portion. The gas bubble removal device can include a coil, a tube, a mesh, and/or a hole that is disposed on or defined in the insertable portion of the elongated body, such as the cooling surface. A low-pressure source, such as a vacuum pump or a Venturi structure, can be fluidly coupled to the gas bubble removal device to remove fluid and bubbles by a suction force after the ECD is inserted into the rectum.

The invention relates to a device for cooling an organ locally, that includes an elongate stem including a far end intended to make contact with an organ to be cooled and comprising including a cooling element having a cold finger, a crystal that has a capacity to cool via excitation at a set excitation wavelength, said crystal being positioned adjacent to said cooling element, an optical guide that is able to convey a light signal at said excitation wavelength and that opens onto said crystal, and an illuminating system including at least one light source, which light source is arranged to emit said light signal.

A fluid warming device for warming fluids and delivering the fluids to a patient comprises an electrical heating component, a temperature sensor, and a control unit. The electrical heating component warms fluid passing through a fluid-carrying tube and may be positioned along the fluid-carrying tube at a desired location or embedded in the fluid-carrying tube while the control unit is positioned such that the display and user inputs are accessible to a caregiver. The control unit activates the electrical heating component until the fluid-carrying tube is warmed to a desired temperature within a Thermal Neutral Zone (TNZ) as sensed by the temperature sensor.

An organ can be cooled to minimize ischemic tissue damage from a vascular occlusion by a thrombus or dissection. A catheter including a thermal member can be used to introduce cold fluid downstream from an arterial occlusion to cool tissue affected by the occlusion. This is particularly useful to minimize neurologic damage from a thrombotic stroke.

The present disclosure provides a device and a method for cooling living tissues for a medical purpose and other purposes. The cooling device includes a cooling medium contacting the living tissues to be cooled. The cooling medium comprises: a first fluid medicine reservoir configured to be installed outside a main body that couples with a medical cooling device and to move into the main body, wherein the first fluid medicine reservoir stores a first fluid medicine to be injected through a hole at a tip of the main body.

An intravital cooling device is for cooling a target site in a living body and includes: a heat exchange part having a flow channel through which a refrigerant passes; and a flexible heat conduction sheet that is directly or indirectly connected to the heat exchange part and arranged to cover the target site, wherein the heat conduction sheet includes a living-body surface, which is a surface on the side that makes contact with the target site, and an outer surface, which is a surface opposite from the living-body surface.