An apparatus includes a body and a head. The head defines a fluid reservoir. The head includes a distal face and a needle. The distal face is configured to engage an exterior surface of a patient's eye at an anterior region of the patient's eye. The needle is configured to extend distally from the distal face. The needle has a length sufficient to extend through a sclera layer of the patient's eye and thereby position at least a portion of a distal tip of the needle in a suprachoroidal space of the patient's eye at an anterior region of the patient's eye. The needle is in fluid communication with the fluid reservoir such that the needle is operable to deliver fluid from the fluid reservoir into the suprachoroidal space of the patient's eye.

An apparatus includes a body, a needle, a catheter, and an actuator assembly. The needle extends distally from the body. The needle has an inner wall defining a needle lumen. The needle lumen is in fluid communication with a fluid port of the body. The catheter is slidably disposed in the needle lumen. The catheter has a catheter lumen. The first actuator assembly is configured to translate the catheter within and relative to the needle. The apparatus may also include an actuator assembly that is configured to rotate the needle relative to the body. The apparatus may be used to first deliver a leading bleb of fluid to the subretinal space in a patient's eye via the needle. The apparatus may then be used to deliver a therapeutic agent to the subretinal space in the patient's eye via the catheter.

An apparatus has a first fluid conduit, a second fluid conduit, a connector member, an first tubular member, a second tubular member, and an inner cannula. The connector member has first and second passageways in which the first and second fluid conduits are positioned, respectively. A portion of the second tubular member is positioned within the lumen of the first tubular member. A proximal portion of the inner cannula is fixedly secured within the lumen of the first tubular member. The inner cannula lumen is in fluid communication with the first and second fluid conduits via the lumen of the first tubular member and the lumen of the second tubular member. The inner cannula may be inserted into the subretinal space of a human eye to deliver a leading bleb of fluid and then deliver a therapeutic agent, without having to withdraw the inner cannula from the subretinal space between the acts of delivering the leading bleb delivering the therapeutic agent.

Configurations are disclosed for a health system to be used in various healthcare applications, e.g., for patient diagnostics, monitoring, and/or therapy. The health system may comprise a light generation module to transmit light or an image to a user, one or more sensors to detect a physiological parameter of the user’s body, including their eyes, and processing circuitry to analyze an input received in response to the presented images to determine one or more health conditions or defects.

An apparatus for administering a drug onto an ocular surface of a subject, the apparatus including a probe holding means for holding a probe within the apparatus. The probe has a first part being made of a bio-compatible material, and a second part being made of a magnetic material, the first part having a proximal end connected to the second part and a distal end opposite to the proximal end, wherein the distal end of the first part is employed to carry the drug. The apparatus also has an induction coil and control circuit, wherein the control circuit controls the induction coil to produce a first magnetic force and a second magnetic force, in an alternating manner, to release the probe in a first direction and to retract the probe in a second direction, respectively, wherein, when released in the first direction, the probe administers the drug from the distal end of the first part upon touching the ocular surface of the subject.

An apparatus for controlling an environment surrounding an eye of a user includes a substrate, a microheater positioned on the substrate, and a liquid reservoir positioned on the microheater. The liquid reservoir includes one or more openings and is at least partially filled with a fluid such as water. The apparatus includes a power source configured to provide power to the microheater. Heat generated by the microheater causes the fluid to be evaporated from the liquid reservoir through the one or more openings, thereby moistening the eye.

A device for administering fluid compositions includes a housing having a first end with an opening. The housing includes a compartment, proximate to the first end, that is capable of holding a liquid reservoir that is at least partially filled with a fluid. The device includes an air pump positioned within the housing, at a second end. The device includes an actuator positioned between the compartment and the air pump. The actuator includes an extendible piston that is configured to extend laterally toward the compartment. During device operation, the actuator causes the piston to extend towards the liquid reservoir and exert a force on the liquid reservoir. The force causes the fluid to be expelled from the liquid reservoir at the first end. The air pump is configured to atomize the fluid at the first end as it is expelled from the liquid reservoir.

An apparatus for treating dry eye, comprising composition chambers respectively containing a first composition and a second composition, wherein the first composition includes 95%-100% of aqueous substances and the second composition includes 95-100% volume of non-aqueous substances; and an air pump that is fluidically connected to the composition chambers and sequentially generates and propels the mists of the first composition and the second composition to a surface that corresponds to a cornea of an eye. The first mist, including droplets of the one or more aqueous substances forms a first film layer that corresponds to an aqueous layer of an artificial tear film, the second mist has a volume within a range of 0.1-3 microliters, and includes droplets of the one or more non-aqueous substances forms a second film layer that corresponds to a lipid layer of the artificial tear film with a thickness within a range of 10 nm-200 nm.

A liquid discharge device includes a liquid storage portion; a tube member; a striking portion; an operation portion; and a discharge port capable of discharging liquid, wherein the tube member has an end portion communicating with an inside of the liquid storage portion, the tube member delivering the liquid from the liquid storage portion to a discharge port side, wherein the tube member has an elastic region elastically deformable at least partly in a longitudinal direction, and wherein when the operation portion is operated, at least a part of the elastic region of the tube member is struck with an impact force by the striking portion to allow the liquid in the tube member to be pushed out and discharged from the discharge port.

An ocular medical injector is provided for drug delivery. A method includes inserting a puncture member of the medical injector into the eye until the puncture member reaches the SCS. The puncture member defines a lumen therethrough. With the puncture member disposed within the SCS, a flexible cannula is advanced distally through the lumen of the puncture member, beyond the distal end portion of the puncture member and along the SCS towards a posterior region of the eye. The flexible cannula has an atraumatic distal tip and defines a lumen therethrough. With the distal tip of the flexible cannula disposed within the SCS beyond a distal end portion of the puncture member, a therapeutic substance is administered to the SCS.