Heart valve prosthesis are disclosed that include a frame or support structure having an inflow portion, a valve-retaining tubular or central portion and a pair of support arms. The inflow portion radially extends from a first end of the valve-retaining tubular portion and the pair of support arms are circumferentially spaced apart and radially extend from an opposing second end of the valve-retaining tubular portion.

This invention relates to the design and function of a compressible valve replacement prosthesis, collared or uncollared, which can be deployed into a beating heart without extracorporeal circulation using a transcatheter delivery system. The design as discussed focuses on the deployment of a device via a minimally invasive fashion and by way of example considers a minimally invasive surgical procedure preferably utilizing the intercostal or subxyphoid space for valve introduction. In order to accomplish this, the valve is formed in such a manner that it can be compressed to fit within a delivery system and secondarily ejected from the delivery system into the annulus of a target valve such as a mitral valve or tricuspid valve.

An implant suitable for being anchored with the aid of mechanical vibration in an opening provided in bone tissue. The implant is compressible in the direction of a compression axis under local enlargement of a distance between a peripheral implant surface and the compression axis. The implant includes a coupling-in face which serves for coupling a compressing force and the mechanical vibrations into the implant, which coupling-in face is not parallel to the compression axis. The implant also includes a thermoplastic material which, in areas of the local distance enlargement, forms at least a part of the peripheral surface of the implant.

A medical device for treating a target site within a lumen having an arcuate portion is provided. The medical device includes a first tubular portion comprising a proximal and distal end, and a second tubular portion comprising a proximal and distal end. A linking portion couples the first and second tubular portions, and an opening defined between the distal end of the first tubular portion and the proximal end of the second tubular portion. At least part of the linking portion is configured to conform to at least a portion of the arcuate portion of the lumen. Associated methods for using a medical device are also provided.

The present disclosure provides tissue matrix packaging devices and methods of use. The packaging can be used to help a tissue matrix sample retain its shape when being stored or transported.

A percutaneous heart valve prosthesis (1) has a valve body (2) with a passage (9) extending between the first and second ends (7, 8) of the valve body (2). The valve body (2) is collapsible about a longitudinal axis (10) of the passage (9) for delivery of the valve body (2) via a catheter (18). One or more flexible valve leaflets (3, 4) are secured to the valve body (2) and extend across the passage (9) for blocking bloodflow in one direction through the passage (9). An anchor device (5), which is also collapsible for delivery via catheter (18), is secured to the valve body (2) by way of an anchor line (6).

This invention is a system for the treatment of body passageways; in particular, vessels with vascular disease. The system includes an endovascular graft with a low-profile delivery configuration and a deployed configuration in which it conforms to the morphology of the vessel or body passageway to be treated as well as various connector members and stents. The graft is made from an inflatable graft body section and may be bifurcated. One or more inflatable cuffs may be disposed at either end of the graft body section. At least one inflatable channel is disposed between and in fluid communication with the inflatable cuffs.

Medical devices and methods for making and using a medical device are disclosed. An example medical device may include a stent that comprises a first covered region formed of one or more interwoven filaments and a covering. The stent may also comprise a second uncovered region adjacent the first covered region. The second uncovered region may include a knitted filament. A first end of the knitted filament may be attached to the first covered region. The knitted filament is configured to be unraveled to remove both the first covered region and the second uncovered region of the stent while the first end of the knitted stent remains attached to the first covered region.

The present invention provides a method for stabilizing a fractured bone. The method includes positioning an elongate rod in the medullary canal of the fractured bone and forming a passageway through the cortex of the bone. The passageway extends from the exterior surface of the bone to the medullary canal of the bone. The method also includes creating a bonding region on the elongate rod. The bonding region is generally aligned with the passageway of the cortex. Furthermore, the method includes positioning a fastener in the passageway of the cortex and on the bonding region of the elongate rod and thermally bonding the fastener to the bonding region of the elongate rod while the fastener is positioned in the passageway of the cortex.

A medical implant is provided that has a first and a second electrospun component with the same type of biodegradable electrospun polymers. In one example, the second electrospun component is separately manufactured from the first electrospun component. Furthermore, the implant is structured such that the first electrospun component and the second electrospun component are assembled or joint together by the same type biodegradable electrospun polymers as in the first electrospun component and the second electrospun component. The assembled implant is a porous, biodegradable medical implant capable of being replaced by naturally ingrown tissue over time upon implantation. Advantages are the avoidance of sutures and the problems associated with the use of sutures, capability of ETR, avoidance of the need for extra materials, allowance for more precise and reproducible assembled structures for which the process could be automated.