Prosthetic heart valve devices and associated methods for percutaneous heart valve replacement are disclosed herein. A transcatheter valve prosthesis configured in accordance herewith includes a frame having a valve support and one or more support arms coupled thereto. The one or more support arms are configured to extend from the second end of the valve support toward the first end when the valve prosthesis is in an expanded configuration. When deployed in the expanded configuration, the one or more support arms have a curvilinear shape, such as a substantially S-shape, that at least partially engages tissue at the native heart valve.

A method of performing joint arthroplasty includes accessing a surface on a bone and supporting a stop with the accessed surface. The method includes positioning an instrument at least partially within the stop, the instrument having a body and a punch, the punch including a portion thereof having a shape similar to a shape of a stem of an implant, and rotating the stop with respect to the accessed surface based upon an indicia on one of the body and the stop so as to position the punch rotationally with respect to the accessed surface at a first orientation. The method further includes moving the body axially with respect to the stop to form a cavity in the bone with the punch at the first rotational orientation, the formed cavity having a shape similar to the stem of the implant, and implanting the stem of the implant into the cavity.

An implant or endoprosthesis suitable to be implanted in human or animal tissue includes two (or more than two) parts to be joined in situ. Each one of the parts includes a joining location, the two joining locations facing each other when the device parts are positioned for being joined together, wherein one of the joining locations includes a material which is liquefiable by mechanical vibration and the other one of the joining locations includes a material which is not liquefiable by mechanical vibration and a structure (e.g. undercut cavities or protrusions) suitable for forming a positive fit connection with the liquefiable material. The joining process is effected by pressing the two device parts against each other and by applying ultrasonic vibration to one of the device parts when the two parts are positioned relative to each other such that the two joining locations are in contact with each other.

A method of performing joint arthroplasty includes preparing a flat surface on a long bone, providing an instrument having a body and a punch extending from the body, the punch including a portion thereof having a shape similar to a stem of an implant, positioning a stop on the flat surface, rotating the stop with respect to the surface of the long bone based upon an indicia on one of the body and the stop so as to position the punch rotationally with respect to the surface to a desired orientation when the instrument is at least partially inserted into the stop, using the instrument to form a cavity in the long bone with the punch at the desired rotational orientation with the instrument inserted at least partially within the stop, the cavity having a shape similar to the stem of the implant, and implanting the stem into the cavity.

An intervertebral implant has a hollow space formed within the implant and accessible through an elongate opening extending through a recessed portion of the side wall, and the hollow space is shaped to receive an engagement portion of a drive shaft of an insertion tool; and the intervertebral implant includes at least two guiding surfaces facing each other and being configured for sliding engagement by a portion of a sleeve of the insertion tool movably holding the drive shaft.

An intervertebral implant has a hollow space formed within the implant and accessible through an elongate opening extending through a recessed portion of the side wall, and the hollow space is shaped to receive an engagement portion of a drive shaft of an insertion tool; and the intervertebral implant includes at least two guiding surfaces facing each other and being configured for sliding engagement by a portion of a sleeve of the insertion tool movably holding the drive shaft.

A device for dispensing medicine to an eye from a container in a non-gravitational manner includes a housing defining a space for receiving the container of medicine. A pair of motors is provided on the housing on opposite sides of the receiving space. Each motor has an actuatable arm. A dispenser assembly is connected to the housing and includes a first end for securing to the container and a second end having a delivery port. The first and second ends are in fluid communication with each other and with the medicine in the container. The arms are actuatable into engagement with the container for urging the medicine out of the container, through the dispenser assembly, and out through the delivery port into the eye.

Implantable valve for treating venous insufficiency having a self-expanding frame encased in polymer having a distal section for blood in-flow, a bulbous center section and a proximal section for blood out-flow. Polymeric leaflets have proximal ends forming a valve outlet which opens and closes in response to venous blood flow and distal portions integral with the inner polymer surface of the distal end of said bulbous section. The leaflets define a predominantly biomimetic sinus region with the bulbous section. Opening of the valve induces flushing of blood from the sinus region for smooth non-traumatic blood flow through said valve.

A prosthetic intervertebral disc is formed of first and second end plates sized and shaped to fit within an intervertebral space and to be implanted from the back of the patient, thereby decreasing the invasiveness of the procedure. The posterior approach provides for a smaller posterior surgical incision and avoids important blood vessels located anterior to the spine particularly for lumbar disc replacements. The first and second plates are each formed of first, second and third parts are arranged in a first configuration in which the parts are axially aligned to form a low profile device appropriate for insertion through the small opening available in the TLIF or PLIF approaches described above. The three parts of both of the plates rotate and translate with respect to one another in situ to a second configuration or a deployed configuration in which the parts are axially unaligned with each other to provide a maximum coverage of the vertebral end plates for a minimum of insertion profile. Upon deployment of the disc, a height of the disc is increased.

An implant or endoprosthesis suitable to be implanted in human or animal tissue includes two (or more than two) parts to be joined in situ. Each one of the parts includes a joining location, the two joining locations facing each other when the device parts are positioned for being joined together, wherein one of the joining locations includes a material which is liquefiable by mechanical vibration and the other one of the joining locations includes a material which is not liquefiable by mechanical vibration and a structure (e.g. undercut cavities or protrusions) suitable for forming a positive fit connection with the liquefiable material. The joining process is effected by pressing the two device parts against each other and by applying ultrasonic vibration to one of the device parts when the two parts are positioned relative to each other such that the two joining locations are in contact with each other.