Clot engagement element comprising bundle of unwoven fibers can be assembled to form an acute stroke treatment device. The device has the capability of forming a three dimensional filtration matrix comprising effective pores with a distribution of sizes. The bundle of fiber design allows the device to be effectively delivered into circuitous cerebral arteries to remove clot that causes stroke. The fiber bundle based filtration matrix offers the advantages of conforming to the changing inner perimeter of a blood vessel during a clot removal process and thus the capability to effectively retain and remove a clot in the vessel. The filtration matrix offers the additional advantage to trap any break-off of the clot during the removal process. A plurality of fiber bundles can be combined to form an effective clot engagement element. Supplemental engagement structure as well as mechanical treatment structure can be integrated into the stroke treatment device. The deployment of the fiber based elements can be facilitated by actuation tool. Aspiration can be employed during the clot removal process.

A fixture includes a first ring member and a second ring member. The first ring member has a first open center and has a first tool connector disposed at a first radial position relative to the first open center. The second ring member has a second open center coupled to the first ring member at a joint. The joint is disposed at a second radial position relative to the first open center. The joint has a second tool connector. The joint is configured to enable movement of the first ring member relative to the second ring member.

A holding device for assembling orthopaedic implants includes: a stand including a columnar structure with an opening formed in the structure and configured to accept a stem and a groove formed in the structure that is configured to accept a portion of an orthopaedic implant to rotatably lock the orthopaedic implant in the opening and a base coupled to the structure and configured to stabilize the structure on a surface; and an angle set including a ring rotatably coupled to the structure and a fork configured to engage the orthopaedic implant and carried by the ring.

There is provided a toric intraocular lens which improves the visibility of a toric axis. The toric intraocular lens is a toric intraocular lens including a lens body provided with an astigmatic axis. A mark indicating the astigmatic axis is formed at an optical surface of an outer rim portion of the lens body, and a length in a radial direction of the lens body and a length in a circumferential direction of the lens body of external dimensions of the mark are different from each other in top view of the optical surface.

This application relates to methods, systems, and apparatus for replacing native heart valves with prosthetic heart valves and treating valvular insufficiency. In some implementations, a heart valve leaflet clipping mechanism includes a delivery apparatus and clipping arms. The clipping arms are coupled to the delivery apparatus. The clipping arms are movable between an open position and a closed position. The two clipping arms are biased to the closed position. The delivery apparatus is configured to hold the clipping arms in the open position. The delivery apparatus is configured to allow the clipping arms to move to the closed position to engage native heart valve leaflet tissue.

Prosthetic heart valve devices for percutaneous replacement of native heart valves and associated systems and method are disclosed herein. A prosthetic heart valve device configured in accordance with a particular embodiment of the present technology can include an anchoring member having an upstream portion configured to engage with tissue on or near the annulus of the native heart valve and to deform in a non-circular shape to conform to the tissue. The device can also include a mechanically isolated valve support coupled to the anchoring member and configured to support a prosthetic valve. The device can further include an atrial extension member extending radially outward from the upstream portion of the anchoring member and which is deformable without substantially deforming the anchoring member. In some embodiments, the upstream portion of the anchoring member and the extension member may be deformed while the valve support remains sufficiently stable.

A method for setting a fill level of a liquid balloon (1) is provided, in which the volume of a liquid-filled receiving space (10) of a pump unit (5) is changed by moving an actuating part (11) of the pump unit (5) by an electric motor (6) which is fed by a battery (7). An actuating process of the actuating part (11) is carried out by a control unit (8) which controls the electric motor (6). The actuating process includes travel control of the actuating part (11) for approaching a target position of the actuating part (11) and after this travel control a check as to whether the pressure of the liquid in the receiving space (10) lies within a permissible filling pressure range around the second filling pressure. If necessary, the position of the actuating part (11) is adjusted.

A device including a liquid balloon (1), a pump unit (5) connected to the liquid balloon (1) via a first connection line (3) for pumping liquid into the liquid balloon (1) and for pumping liquid out of the liquid balloon (1), an electric motor (6) for driving the pump unit (5), a battery (7) for supplying energy to the electric motor (6) and an electronic control unit (8) for controlling the electric motor (6). The device further includes a manual actuating unit (51) for removing liquid from the liquid balloon (1) and for pumping liquid back into the liquid balloon (1), the manual actuating unit (51) having a flexible pump body (30) which is connected to the liquid balloon (1) via a second connection line (31).

A method for transcatheter delivery to a native heart valve needing replacement. A first component is attached to the native annulus upstream of the native leaflets maintaining native leaflet function, and is held to the native annulus by barbs that are activated by a torus balloon after the first component is fully expanded. The torus balloon can be implanted along with the support frame. A limiting cable restricts further expansion of the first component and holds a second component that contains the replacement leaflets.

The invention relates to a safety cartridge (1) for a removable vena cava filter (20), having a proximal end (2) and a distal end (3) and having an inner channel (4) extending between the ends. The cartridge is characterized in that it comprises, on the distal end (3) thereof, a linking device (5) for forming a link with a catheter (30) and, in the inner channel thereof, a projection (6) having a limited size in the axial direction of the cartridge (1) so as to locally reduce the cross-section of the channel (4).