A method of forming a three-dimensional object, wherein said three-dimensional object is an insert for use between a helmet and a human body, is described. The method may use a polymerizable liquid, or resin, useful for the production by additive manufacturing of a three-dimensional object, comprising a mixture of (i) a light polymerizable liquid first component, and (ii) a second solidifiable component that is different from said first component.

A method of forming a three-dimensional object is carried out by: (a) providing a carrier and an optically transparent member having a build surface, the carrier and the build surface defining a build region therebetween; (b) filling the build region with a polymerizable liquid, the polymerizable liquid including a mixture of (i) a light polymerizable liquid first component, and (ii) a second solidifiable component that is different from the first component; (c) irradiating the build region with light through the optically transparent member to form a solid polymer scaffold from the first component and also advancing the carrier away from the build surface to form a three-dimensional intermediate having the same shape as, or a shape to be imparted to, the three-dimensional object, and containing the second solidifiable component carried in the scaffold in unsolidified and/or uncured form; and (d) concurrently with or subsequent to the irradiating step, solidifying and/or curing the second solidifiable component in the three-dimensional intermediate to form the three-dimensional object.

A thermoplastic polyurethane (TPU) foam product with high flatness, and a preparation method and a use thereof are provided. The TPU foam product is prepared by processing aliphatic thermoplastic polyurethane (ATPU) beads with a melting range of 20° C. to 50° C. and a melting point of 90° C. to 160° C. by a physical gas foaming process to obtain foamed ATPU beads and heating the foamed ATPU beads with a heat source to make the foamed ATPU beads fused. The TPU foam product with high flatness has a density of 0.08 g/cm.sup.3 to 0.8 g/cm.sup.3 and a flatness value of less than 2 mm, and the flatness value is determined by a fixed-length ruler. The TPU foam product not only has high flatness such that diversified designs are allowed for a surface of the product, but also has high resilience.

The present invention provides a stabilising composition, comprising: a) a first phenolic antioxidant comprising one or more phenolic compounds having the structure of formula (I): ##STR00001##  wherein R.sub.1 is a linear or branched alkyl group having from 12 to 20 carbon atoms; and b) one or more second phenolic antioxidants independently selected from:  a mono-hydroxybenzene having lower steric hindrance than the first phenolic antioxidant;  a di-hydroxybenzene; and/or  a tri-hydroxybenzene.

The present invention relates to thermoplastic polyurethanes obtainable or obtained by reacting at least a polyisocyanate composition comprising at least one polyisocyanate, at least one chain extender, and at least one polyol composition, wherein the polyol composition comprises at least one polyester polyol (P1) which is obtainable by reacting an aliphatic dicarboxylic acid having 2 to 12 carbon atoms and a mixture (M1) comprising propane-1,3-diol and a further diol (D1) having 2 to 12 carbon atoms, preferably butane-1,4-diol. The present invention also relates to a preparation process for such thermoplastic polyurethanes and also to the use of a thermoplastic polyurethane according to the invention or of a thermoplastic polyurethane obtainable or obtained by a process according to the invention for the production of extrusion products, films and shaped bodies or for the production of polymer compositions.

The present application relates to fibers having a diameter of 1 nm to 10,000 nm, of one or more biocompatible polymers, wherein the polymers have a backbone which includes a positively charged component from a zwitterionic moiety. Additionally, this application discloses an implantable therapeutic delivery system and its method of formation, comprising a housing defining a chamber, wherein said housing is porous and formed from the fibers. Inside of the housing includes a preparation of cells which release a therapeutic agent from the chamber. The implantable therapeutic delivery system can be used in the treatment of diabetes.

Polyurethane material for indicating pH at a locus, preferably as indication of presence of microbes, comprising a polyurethane network having immobilised therein one or more hydrophilic copolymers, the or each said copolymer comprising: hydrophilic monomer; and indicating monomer, which provides an indication in response to a change in hydrophilic state of said hydrophilic monomer and/or copolymer; characterised in that the or each copolymer further comprises one or a plurality of ionisable groups or moieties or polymerisable monomers having one or more characteristic pKa values in the range 5 to 10 and which are responsive to pH at the locus in the range pH 5 to pH 10 and in that hydrophilic state of hydrophilic copolymer is dependent on ionisation of said ionisable groups, moieties or monomers; kit and device comprising the material and process for preparation thereof; and use in detecting or sensing microbes or pH.

Described herein are melt-extrudable biodegradable inks for 3D-printing, methods of using the inks, and kits including the inks, to prepare implantable grafts, such as artificial tympanic membrane devices or artificial cartilage, nerve conduit, tendon, muscle tissue, or bone devices.

A reactive mixture and method for making a thermoplastic polyurethane (TPU) flexible foam having a predominantly open-cell structure (open-cell content of ≥50% by volume calculated on the total volume of the foam and measured according to ASTM D6226-10) and an apparent density below 200 kg/m.sup.3.

Provided is a composition capable of forming a cured product excelling in adhesion to a substrate, hardness, scratch resistance, and chemical resistance. The composition of the present disclosure contains a polyol compound (A) and an isocyanate compound (B) The polyol compound (A) includes a compound (a1) represented by Formula (1) below, where R.sup.1 to R.sup.3 each are a group represented by Formula (1a), the compound (a1) having a number average molecular weight (calibrated with polystyrene standard) of 800 or greater. The isocyanate compound (B) includes a polyisocyanate compound having an isocyanurate skeleton.