A vein cover that can reduce or prevent intimal thickening by delivering blood to the downstream veins while gradually buffering the blood pressure, pulse pressure, and blood flow rate of the blood flowing through the lumen is provided.

A cylindrical vein cover (10) is to be placed outside a vein (4) that is anastomosed to an artery (3) or to an artificial vessel (5), and has a portion (A) that has a 10% elastic index of 25 N or less when the inner diameter of the vein cover (10) is expanded by 10% from its natural state.

A prosthetic valve includes a frame and a flow control component. The frame has an aperture extending through the frame about a central axis. The flow control component is mounted within the aperture and is configured to permit blood flow in a first direction approximately parallel to the vertical axis from an inflow end to an outflow end of the flow control component and to block blood flow in a second direction, opposite the first direction. The frame has an expanded configuration with a first height along the central axis, a first lateral width along a lateral axis perpendicular to the central axis, and a first longitudinal length along a longitudinal axis perpendicular to the central axis and the lateral axis. The frame has a compressed configuration with a second height less than the first height and a second lateral width less than the first lateral width.

Methods, devices and materials are for in situ formation of an implant for treating a nerve. A treatment site is positioned within a cavity defined by a form. The form may facilitate placement of a nerve stimulating device adjacent to the nerve to facilitate nerve regeneration. An in situ forming gel may be delivered in the form to surround the nerve. Access to the nerve treatment site may be open surgical or percutaneous.

Prosthetic heart valves having elastic leaflets and an elastic support structure are described. The support structure can store a load transferred from the leaflets as potential energy and then release it in the form of kinetic energy to exhibit a precursory transition from the closed position to the open position. The support structures can exhibit a sinusoidal movement profile at a base edge during the precursory transition.

Porous implantable devices for housing one or more therapeutic agents are disclosed herein. The implantable devices include a porous outer wall defining an interia or void. The interior void houses a carrier material carrying a first therapeutic agent. The implantable devices are made by patterning at least a portion of a polymerizable substrate into a polymerized three-dimensional porous outer wall surrounding an interior void. This can be achieved by two-photon polymerization techniques. A first therapeutic agent is then added to the interior void, which is then sealed. Methods of treating diseases using the implantable devices are disclosed herein. The methods include implanting the implantable device at a target area and locally releasing a therapeutically effective dosage of a first therapeutic agent from the interior void. The implantable devices can also be used in methods of screening potentially therapeutic agents for desired biological responses.

In an aspect, the present disclosure provides a cartridge that is pre-loaded with a surgical mesh, where the cartridge is configured to be inserted into an internal body cavity of a subject and for the surgical mesh to be deployed while the cartridge is in the internal body cavity of the subject. In another aspect, the present disclosure provides a surgical robotic system comprising a set of sensors embedded thereon, wherein the surgical robotic system is configured to perform a surgical hernia repair procedure with increased consistency.

This glenoidal component for a shoulder prosthesis comprises a base which may be immobilized on the glenoid cavity of a shoulder, and an element provided to be mounted on this base and forming a convex surface of articulation centred on an axis of symmetry. This axis of symmetry is non perpendicular to a rear face of the base intended to abut against the glenoid cavity, this making it possible to compensate a defect in parallelism between the resectioned surface of the glenoid cavity and the axis of the patient's spinal column. A surgeon can select the component in which the axes of symmetry of the components are oriented differently with respect to their rear faces.

A device for remodeling a penis, comprising a generally cylindrical hollow assembly having a lumen extending between proximal and distal ends, the distal end being in communication with the lumen to facilitate insertion of the penis into the lumen, the generally cylindrical structure having an interior surface facing the lumen and an exterior surface facing away from the lumen, a longitudinal direction and a transverse direction, the transverse direction being orthogonal to the longitudinal direction, the generally cylindrical assembly adapted to snugly and resiliently grip the penis, and includes an elastic fabric with one or more regions reinforced with a plastically deformable member.

A double-layer lumen stent (100) includes a main body lumen stent (10) and an outer-layer skirt stent (20) surrounding an outer wall of the main body lumen stent (10); the outer-layer skirt stent (20) includes a support structure (21) and a cover layer (22) arranged on the support structure (21); one end of the outer-layer skirt stent (20) is connected to the outer wall of the main body lumen stent (10); the other end of the outer-layer skirt stent (20) is an opening structure (24) composed of the support structure (21); and the cover layer (22) is formed into an oblique cut shape at an edge of the opening structure (24). In the double-layer lumen stent (100), when a clinician releases the double-layer lumen stent (100) at a human tissue such as a vessel through a delivery device, constraint from the cover layer (22) to the opening structure (24) of the outer-layer skirt stent (20) can be reduced, and the adhesion between the cover layer (22) at the opening structure (24) on the outer-layer skirt stent (20) and the main body lumen stent (10) is reduced, thereby reducing release resistance to the outer-layer skirt stent (20) during the release process of the double-layer lumen stent (100).

An implantable vein frame is contemplated in which two ring members are rigidly joined in spaced axial alignment via one or more interconnecting members. One of the one or more interconnecting members defines a protruding region that acts upon the implant placed within the frame and/or the vein that the vein frame is placed within to define a sinus region. The implant is placed within and scaffolded by the vein frame, and the vein frame is subsequently inserted within a vein via a venotomy, or interposed between two vein segments via vein interposition graft. The vein frame acts to support the structural integrity of the implant, and to scaffold and anchor the implant in place with the vein.