The invention provides a sustained release intraocular drug delivery device comprising: (a) a polymeric matrix core into which at least one therapeutic agent is mixed, and; (b) a polymeric coating completely surrounding said polymeric matrix material; wherein said polymeric matrix core and polymeric coating are insoluble and inert in ocular fluids, and wherein said sustained release intraocular drug delivery device has a compliant annular segment shape and is to be inserted into the sulcus of the intact and/or pseudophakic eye.

One aspect of the present disclosure relates to a breast implant sizer assembly for accurately sizing surgically implantable breast implants prior to implantation. The breast implant sizer assembly can include an inflatable, flexible shell containing an adjustable volume of liquid and a valve assembly, once filled with liquid, that is associated with the shell and configured like an anatomically correct nipple. The breast implant sizer assembly can have a size, shape, and weight that mimics the size, shape, and weight of a breast implant. In addition, the breast implant sizer assembly is disposable, intended for single use by a patient, allows for use in the home and everyday settings, and provides accurate, actionable information to a surgeon or other medical professional in regards to selecting actual breast implant sizes for clinical use.

A template 13 comprises a cusp base forming part 11 having a shape corresponding to a cusp base is provided to obtain cusp material for dispersing stresses exerted on the cusp. Such a cusp forming template may further comprise wing forming parts 15 corresponding to wing parts provided outside the cusp base forming part 11. As examples of the wing forming part, there may be employed a single or plural holes provided at a part or parts corresponding to the outline of each wing, and guide parts provided at parts corresponding to the outline of wings.

This disclosure relates to systems and methods for performing ossicular reconstructions. An exemplary ossicular reconstruction system may include one or more adjustable prosthetic devices and micro-measuring devices. The adjustable prosthetic devices may be adjusted in terms of length, angulation, or both.

An ancillary device capable of assisting in the two anastomosis procedures necessary for replacing a segment of a corporeal duct with a prosthesis, and the connection of said prosthesis without the need for any suture. An optimised kit for anastomosis including the ancillary device is also provided. The ancillary device for anastomosis, including an elongate body provided with a longitudinal through channel intended to receive a tubular prosthesis therein, the body of the device including, on a proximal side, a handling portion and, on a distal side, a shaping assembly formed by a plurality of the lamellae defining a compression area of the prosthesis. The body of the device includes a closable longitudinal opening giving access to the longitudinal channel intended to receive the prosthesis.

A penile construction template may include an adhesive film configured for adhesion to donor skin. The penile construction template may include a first section defined on the adhesive film to identify an external phallus skin flap of the donor skin to be extracted while the adhesive film is adhered to the donor skin, and a second section defined on the adhesive film to identify a de-epithelialized skin flap of the donor skin to be extracted while the adhesive film is adhered to the donor skin. An implantable device for urethra construction may include a tubular scaffold configured to be coupled to a natal urethra of a patient, the tubular scaffold being seeded with urethral cells of the patient for growth of a urethral segment on the tubular scaffold therefrom while disposed within a body of the patient.

A pancreatic stent includes a main body convertible between a compressed configuration for delivery and an expanded configuration once deployed, the main body including an inner surface defining a stent lumen and an outer surface. A plurality of drainage features are formed within the outer surface of the main body, the plurality of drainage features permitting placement of the pancreatic stent within a patient's pancreas without blocking side branches of the pancreas.

A mandrel for molding polymer valve leaflets for heart valve prostheses is disclosed, including a body portion including an outer surface with ridges and contoured surfaces corresponding to the leaflets, the upper edge of the contoured surfaces corresponding to the free upper edge of the leaflets, and the mandrel including a mandrel extension above the body portion, and a gap extending around the mandrel between the upper edge of the contoured surface and the mandrel extension. A process for producing these polymer valve leaflets is also disclosed by dip coating with this mandrel and removing the polymer film created at the gap, preferably by applying suction or blowing thereto.

A fenestration template device includes a main body extending along a longitudinal axis between a first end and a second end of the device. The device includes an outer surface extending from the first surface to the second surface. The device includes a central lumen defined by the main body along the longitudinal axis, the central lumen extending from a first opening at the first surface to a second opening at the second surface. The device includes a plurality of side lumens defined by a plurality of side openings in the outer surface and extending from the side openings, through the main body, and into the central lumen. The device is configured for accepting a tube of an ocular implant (e.g., a glaucoma drainage implant) in the central lumen. The device is further configured for accepting a needle or suturing device in the plurality of side lumens.

In a method of creating a modified tissue graft, at least one exterior surface of a graft is modified by compressing, cutting and/or removing one or more portions thereof, such as to create designed surface features which cause the tissue graft to have characteristics for a specific anatomical area. The modified tissue graft may comprise a medicated graft, such as by associating medicants with the surface features, or by associating a second graft or layer with a modified base tissue graft layer, where medicants are associated with the second graft or layer. The tissue graft may be modified by pressing a specially configured template or die, such as having blades thereon, into the tissue graft, such as to create a pattern of partial depth cuts.