An orthopaedic implant can replace a joint in a patient. The orthopaedic implant includes a first component having a first component surface and a second component having a second component surface. The first component surface and the second component surface mate at an interface. The first component surface includes a metal substrate, a nanotextured surface, a ceramic coating, and a transition zone. The nanotextured surface is disposed directly upon the metal substrate and has surface features in a size of 10.sup.−9 meters. The ceramic coating conforms to the nanotextured surface and includes a plurality of bio-active sites configured to attract and retain calcium and phosphorous cations. The transition zone is disposed between the metal substrate and the ceramic coating. The transition zone includes a concentration gradient transitioning from the metal substrate to the ceramic coating and there is no distinct interface between the metal substrate and the ceramic coating.

Interbody fusion devices and related methods of manufacture are described herein. An example interbody fusion device can include a plurality of vertebral endplates, and a body extending between the vertebral endplates. The body and the vertebral endplates can define an internal cavity. Additionally, each of the vertebral endplates can include a lattice structure and a frame surrounding the lattice structure, where the lattice structure being configured to distribute load. Each of the vertebral endplates can also include a plurality of micro-apertures having an average size between about 2 to about IO micrometers (μm), and a plurality of macro-apertures having an average size between about 300 to about 800 micrometers (μm).

An orthopedic implant having a subsurface level ceramic layer generally includes a base material, an intermix layer molecularly integrated with the base material that includes a mixture of the base material and a plurality of subsurface level ceramic-based molecules implanted into the base material, and an integrated ceramic surface layer molecularly integrated with and extending from the intermix layer forming at least part of a molecular structure of an outer surface of the orthopedic implant. The integrated ceramic surface layer and the base material thereafter cooperate to sandwich the intermix layer in between.

The process for producing an orthopedic implant having an integrated ceramic surface layer includes steps for positioning the orthopedic implant inside a vacuum chamber, emitting a relatively high energy beam into the at least two different vaporized metalloid or transition metal atoms in the vacuum chamber to cause a collision therein to form ceramic molecules, and driving the ceramic molecules with the ion beam into an outer surface of the orthopedic implant at a relatively high energy such that the ceramic molecules implant therein and form at least a part of the molecular structure of the outer surface of the orthopedic implant, thereby forming the integrated ceramic surface layer.

A composition and medical implant made therefrom, the composition including a thick diffusion hardened zone, and preferably further including a ceramic layer. Also provided are orthopedic implants made from the composition, methods of making the composition, and methods of making orthopedic implants from the composition.

The present disclosure in one aspect provides a surgical implant comprising an upper bone contacting surface comprising a plurality of irregularly shaped pores having an average pore size, where the pores are formed by a plurality of struts, a lower bone contacting surface comprising a plurality of irregularly shaped pores having an average pore size, wherein the pores are formed by a plurality of struts; and a central body comprising a plurality of irregularly shaped pores having an average pore size, wherein the pores are formed by a plurality of struts, wherein the average pore size on the upper and lower bone contacting surfaces is different than the average pore size on the central body.

Provided herein is an implant made of a biocompatible ceramic of synthetic origin obtained by additive manufacturing. The implant may include a dense portion featuring a material density by volume greater than 70%, and a porous portion connected to the dense portion by a connection zone. The porous portion may have an average macroporosity having a material density ranging from 30% to 70% by volume and cavities defining cavity sections, with a diameter ranging from 0.3 mm to 1.2 mm. The dense portion and the porous portion may define an external surface. The cavities may open onto the external surface.

The dual mobility acetabular component includes an acetabular cup and a liner that engage one another in a relatively static relationship by way of a Morse taper. The acetabular cup and the liner may be manufactured from a metal material (e.g., titanium) that decreases the energy differential therebetween, to limit or eliminate the galvanic cell phenomenon that forms between adjacent surfaces thereof as a result of body fluid therein that remains captured in small gaps or spaces due to capillarity. As such, the dual mobility acetabular component may experience reduced fretting compared to conventional hip joints known in the art.

The invention provides an implant system for treating bone defects or discontinuities and a method for producing such an implant system. The implant system (100) comprises: a first implant element (110) which is insertable or inserted into a bone defect or a discontinuity (2) of a human bone (1), a second implant element (120) which is fixable or fixed to the human bone (1), wherein the first implant element (110) is attachable or attached to the second implant element (120) by means of at least one biodegradable connection means (125) in order to fix the first implant element (110) relative to the human bone (1), wherein the first implant element (110) comprises a shell section (111) and an inner section (112) at least partially enclosed by the shell section (111), wherein the shell section (111) has a first pore-and-strut structure, PSS, and the inner section (112) has a PSS differing from the first PSS.

Provided herein are biomimetic osteochondral implants that are generally useful for the at least partial resurfacing of damaged cartilage within a joint. The implants are constructed to have a modular, layered structure in which the physical properties (e.g., stiffness and lubricity) or dimensions of each layer can be adjusted (e.g., by using the appropriate material and controlling the thickness thereof) based on the anatomy to be replaced. For example, the material and or thicknesses of the layers can be selected to approximate the physical properties and/or dimensions of cartilage (and, optionally, chondral and subchondral bone). Also provided herein are methods of treatment involving the use of said biomimetic osteochondral implants to repair an osteochondral defect in a joint.