Silkworm silk, has been processed into a variety of new material formats including, hydrogels, ultrathin films, thick films, conformal coatings, 3D porous or solid matrices, fibers and many related material formats. Silk is processed in an all water-based, room temperature, neutral pH environment, is mechanically stable, edible, and biocompatible. Given the favorable material properties, the use of silk-based inks have been used in a variety of controlled chemical and biological material fabrication on the micro- and nano-scale. Tuning of the properties of silk-based inks has led to the utilization of more diverse printing techniques and has expanded the scale and function of the printed substrates.

Silkworm silk, has been processed into a variety of new material formats including, hydrogels, ultrathin films, thick films, conformal coatings, 3D porous or solid matrices, fibers and many related material formats. Silk is processed in an all water-based, room temperature, neutral pH environment, is mechanically stable, edible, and biocompatible. Given the favorable material properties, the use of silk-based inks have been used in a variety of controlled chemical and biological material fabrication on the micro- and nano-scale. Tuning of the properties of silk-based inks has led to the utilization of more diverse printing techniques and has expanded the scale and function of the printed substrates.

A novel ultrasonic oscillation-induced sericin extraction method produces a high-molecular-weight sericin solution from silk cocoon threads at room temperature. In one embodiment, unique pH variation-resistant alkaline ionic water is produced from a novel strongly-alkaline ionic water generator device, wherein the unique pH variation-resistant alkaline ionic water is subsequently utilized as a beneficial solvent that contributes to the feasibility of the novel ultrasonic oscillation-induced sericin extraction method at room temperature. The high-molecular-weight sericin solution produced and coated in a glove provides a high coating adhesion for economical manufacturing of sericin-coated gloves, while also providing superb skin moisturizing and protection properties. Furthermore, once coated in a glove, the high molecular weight of sericin beneficially resists a rapid skin seepage of sericin to human skin layers, thereby acting as natural moisturizing factor (NMF) simulants on top of the human skin layers when the glove is worn.

A novel ultrasonic oscillation-induced sericin extraction method produces a high-molecular-weight sericin solution from silk cocoon threads at room temperature. In one embodiment, unique pH variation-resistant alkaline ionic water is produced from a novel strongly-alkaline ionic water generator device, wherein the unique pH variation-resistant alkaline ionic water is subsequently utilized as a beneficial solvent that contributes to the feasibility of the novel ultrasonic oscillation-induced sericin extraction method at room temperature. The high-molecular-weight sericin solution produced and coated in a glove provides a high coating adhesion for economical manufacturing of sericin-coated gloves, while also providing superb skin moisturizing and protection properties. Furthermore, once coated in a glove, the high molecular weight of sericin beneficially resists a rapid skin seepage of sericin to human skin layers, thereby acting as natural moisturizing factor (NMF) simulants on top of the human skin layers when the glove is worn.

The present invention relates to a method for preparing a surgical anti-adhesion barrier film comprising the following steps: a°) a first solution, comprising an oxidized collagen is prepared, b) a polyphosphate compound is added to the solution of a) in a quantity so as to obtain a concentration of polyphosphate ranging from 0.007 to 0.7%, by weight, with respect to the total weight of the solution, c) the pH of the solution obtained in b) is adjusted to about 9 by addition of a base or to about 5.1 by addition of an acid, d) a diluted solution is prepared by adding water to solution of c), e) a first layer of solution obtained in c) is casted on an inert support, f) before complete gelation of the layer obtained in d), a second layer, of diluted solution obtained in d) is applied on top of said first layer and let to gelify, g) the gelified first and second layers are dried to obtain a film. The invention further relates to a film obtainable by such a method and to a surgical implant comprising a prosthetic fabric and such a film.

Provided is a water-absorbing and quick-drying property-imparting agent capable of easily imparting water-absorbing and quick-drying properties to various materials or articles in a simple process, and a method capable of easily imparting water-absorbing and quick-drying properties to predetermined materials or articles.

A water-absorbing and quick-drying property-imparting agent containing modified fibroin as an active ingredient, and a method for imparting water-absorbing and quick-drying properties to an article, the method including a step of incorporating modified fibroin into the article.

Provided is a water-absorbing and quick-drying property-imparting agent capable of easily imparting water-absorbing and quick-drying properties to various materials or articles in a simple process, and a method capable of easily imparting water-absorbing and quick-drying properties to predetermined materials or articles.

A water-absorbing and quick-drying property-imparting agent containing modified fibroin as an active ingredient, and a method for imparting water-absorbing and quick-drying properties to an article, the method including a step of incorporating modified fibroin into the article.

The present disclosure provides functional fibrous material comprising fibers associated with hydrogel containing micro-flakes. The present disclosure also provides a method of forming hydrogel micro-flakes having embedded therein at least one microorganism and a method of preparing functional fibrous material, both methods comprise a step of subjecting a mixture of hydrogel and microbial material to high shear forces to form micro-flakes comprising the hydrogel with at least one microorganism embedded therein. Further provided is a method of treatment of a target comprising contacting the target with the disclosed functional fibrous material as well as the micro-flakes disclosed herein.

Chemically linked silk fibroin coatings and methods of making and using thereof are disclosed herein. Also disclosed are articles coated with such coatings, which can include chemical or physical modifiers.

Chemically linked silk fibroin coatings and methods of making and using thereof are disclosed herein. Also disclosed are articles coated with such coatings, which can include chemical or physical modifiers.