Apparatus and methods for lyophilizing and sealing a medicament within a medical delivery device having an opening. The apparatus may include a stopper for sealing the opening. The stopper may have one or more elongated members extending from a base, in a direction that is parallel to a central axis of the base. One or more of the members may be set radially away from the axis and define a coaxial central well. The member or members may define a void. The elongated member or members may engage a device inner wall and support the base away from the opening. The void may provide gas exchange between a device interior and a device exterior. The gas may be a lyophilization byproduct that escapes from the device interior between the inner wall, the base and the member or members. The stopper may be advanced into the device to seal the opening.

A shield for a port closure of a medical container includes housing comprising two movably connected housing segments, each having a hollow interior and an open end, movable between open and closed orientations. A lock assembly is structured to define a fixed locked connection between the housing segments in the closed orientation and includes first and second lock members connected within different ones of the housing segments in a non-accessible location when the housing segments are in the closed orientation. A retainer is disposed within the housing in a capturing orientation relative to the closure therein, concurrent to the closed orientation. A latch assembly is connected to the housing segments and structured to retain said housing segments in said closed orientation, independently of and concurrently with the fixed locked connection of the lock assembly.

In one aspect of the subject invention, a labeling shell is provided for a drug vial having a glass reservoir and an opening sealed by an elastomeric stopper, the labeling shell including: a polymeric tubular body formed to accommodate the reservoir of the drug vial, the tubular body having a first open end defining a first opening smaller than a diameter of the reservoir of the drug vial so as to prevent passage therethrough of the reservoir, wherein the elastomeric stopper is exposed through the first end with the reservoir being accommodated in the tubular body; and, a polymeric cap removably mountable to the tubular body to selectively cover the elastomeric stopper of the drug vial with the reservoir being accommodated in the tubular body. Advantageously, the subject invention provides a labeling surface for a drug vial, while also providing restricted access to the drug vial to limit tampering therewith.

An automated medication dispenser system is disclosed. The system includes a dispenser device comprising a medication dispensing and storage module, a dispensing drive and control mechanism, and a communications interface. A third party communications host is in communication with the dispenser device, and has administration software with executable instructions for control of the dispensing drive and control mechanism to dispense medication from the medication dispensing and storage module. The communications interface is in communication with the third party communications host.

The subject matter described herein is directed to stable L-cysteine compositions for injection, comprising: L-cysteine or a pharmaceutically acceptable salt thereof and/or hydrate thereof in an amount from about 10 mg/mL to about 100 mg/mL; Aluminum in an amount from about 1.0 parts per billion (ppb) to about 250 ppb; cysteine in an amount from about 0.01 wt % to about 2 wt % relative to L-cysteine; pyruvic acid in an amount from about 0.01 wt % to about 2 wt % relative to L-cysteine; a pharmaceutically acceptable carrier, comprising water; headspace O.sub.2 that is less than 1.0%; dissolved oxygen present in the carrier in an amount from about 0.01 parts per million (ppm) to about 1 ppm, wherein the composition is enclosed in a single-use container having a volume of from 10 mL to 100 mL. Also described are compositions for a total parenteral nutrition regimen and methods for their use.

The present disclosure describes a method that includes receiving a plurality of packaging units made of glass; coating at least a portion of an outer surface of each packaging unit with low-friction coating; curing the low-friction coating applied to the outer surface of each packaging unit; receiving a container configured to store the plurality of packaging units; and arranging each packaging unit in the container with the outer surface of each packaging unit able to touch the outer surface of one or more adjacent packaging units.

In accordance with one or more embodiments of the invention, a stand up device is presented, including a substantially ring-shaped grip portion, a height adjustment tube, a frame, a securing mechanism, and a plurality of legs. The stand up device provides additional support when installed with a mattress, and facilitates getting up from, and standing up from, a bed.

A filling aid. The filling aid includes a locking portion including a groove feature; and a locking feature having a locked and an unlocked position; and a filling syringe holder slidably attached to the locking portion, the filling syringe holder including a filling needle cradle portion having a tongue feature; and a needle housing portion comprising at least one tab having a starting position and a filling position, wherein the groove feature configured to accommodate the tongue feature, and wherein the locking feature interact with the filling syringe holder wherein when the locking feature moves from the locked position to the unlocked position the needle housing portion moves from the starting position to the filling position.

A transport or packaging container accommodating a plurality of supporting structures for closures, for transporting or packaging closures for closing cartridges for use in pharmaceutical, medical or cosmetic applications, in which the transport or packaging container is box-shaped and includes a bottom, which is closed or sealed by a seal, upstanding lower side-walls extending essentially perpendicularly from the bottom, a circumferential supporting step extending horizontally from the upstanding lower side-walls, upper side-walls extending upward from said circumferential supporting step, and a circumferential flange formed at upper ends of the upper side-walls; and the plurality of supporting structures for closures is accommodated inside the transport or packaging container.

Disclosed is a method of sealing a syringe barrel having a syringe tip with a collar. The syringe tip is sealed with a resilient closure. A tamper evident syringe tip cap comprising a cap member and a sleeve member separated by an annular first breaking line is then pushed over the resilient closure, to couple the proximal end of the sleeve member with the collar. The distal end of the resilient closure is accommodated in the cap member and protrudes beyond the sleeve member. The first breaking line is bridged by a coupling strip. For use of the syringe and providing access to the closure, the first breaking line is broken by pivoting the cap member away. The sleeve member remains coupled to the collar. Further tearing the cap member downward causes breaking a second breaking line provided in the sleeve member, thereby enabling removing the entire syringe tip cap.