An oxidation and grafting method for grafting a bioactive polymer, such as polyNaSS, onto an article, in particular a polymer or ceramic article. The method comprises a step of oxidation by ozonation and a step of grafting by radical polymerisation in a polymerisation station having a first reactor. The two steps of oxidation and grafting are carried out consecutively in different solutions in the reactor of the polymerisation station.

A blended polymer comprising, an amorphous thermoplastic polymer and a thermoplastic semi-crystalline polymer, each of the polymers being essentially miscible in the other and being blended at a weight ratio of amorphous polymer/semi-crystalline polymer of greater that 0.05 to about 20 forms a melt blown nonwoven fabric having essentially no defects with long fiber lengths having uniform diameters. The nonwoven fabrics when used as a filter may have greater than 95% efficiency at a pressure drop of less than 2 mm Hg even after being exposed to high temperatures (˜70° C.) for an hour or more.

The invention relates to a method for producing a laminar product suitable for manufacturing external covers of sanitary towels and nappies, formed by a polymeric coating deposited over the surface of a non-woven fabric substrate, as well as to the laminar product obtained using said method. The method comprises the following steps: obtaining adhesive polymeric mixtures, feeding the mixtures, in a melted state, to a curtain-type applicator, coating the substrate with the adhesive polymeric mixtures, and winding the laminar product obtained. The product obtained comprises a polymeric coating bonded to the non-woven fabric substrate, wherein the polymeric coating consists of an adhesive polymeric layer that has a reduced thickness, ranging between 1 and 10 micra, said product being suitable for medical and personal hygiene applications.

The instant invention provides electrospun fiber compositions comprising one or more polymers and one or more biologically active agents. In specific embodiments, the biologically active agents are nerve growth factors. In certain embodiments, the electrospun fiber compositions comprising one or more biologically active agents are on the surface of a film, or a tube. The tubes comprising the electrospun fiber compositions of the invention can be used, for example, as nerve guide conduits.

Three dimensional nanofiber structures are provided and methods of production thereof.

The present invention implements a set of grooves/ridges created on Ti at the circumferential direction to increase surface area of implant in contact with bone. These grooves/ridges protect nanofiber matrix (NFM) made with Polycaprolactone (PCL) electrospun nanofiber (ENF) and collagen at the groove from physiological loading. Controlled fabrication of a ridge made with titanium nitride (TiN) around the circumference of Ti is provided using a plasma nitride deposition technique. PCL ENF may be deposited along the sub-micrometer grooves using the electrospin setup disclosed. The method provides for fabrication of microgroove on Ti using machining or TiN deposition and filling the microgrooves with the NFM. This method has proven through experimentation to be successful in increasing in vivo mechanical stability and promoting osseointegration on Ti implants. The immobilization of MgO NP and FN with the PCL-CG NFM on microgrooved Ti as provided in the invention optimizes biological performances of Ti.

A tracker system for use in image guided surgery is disclosed. The tracker system may couple to wet tissue and may include a navigation tracker and a base pad that couple to each other. The base pad may be fabricated from a plurality of nonwoven nanofibers. The base pad is configured to couple to body tissue of a patient via at least one of adsorption, hydration equilibrium, and macromolecular interpenetration.

An object of the present invention is to improve spinnability, productivity, and tensile strength of a polyester fiber containing poly(3-hydroxybutyrate-co-3-hydroxyhexanoate). By spinning the polyester resin containing the poly(3-hydroxybutyrate-co-3-hydroxyhexanoate) at a high spinning velocity, the spinnability, productivity, and tensile strength of the polyester fiber can be improved.

The present disclosure relates to fibers implantable in the body of a human or animal and processes for manufacturing such a fiber. The fiber undergoes a reduction in surface area to volume ratio of a factor of 1.05-10 upon injection in the human or animal body. In an embodiment, a process for manufacturing a fiber comprises extruding a biodegradable polymer into a fiber capable of fitting in a syringe needle of at least 25 Gauge, and cooling the fiber below its dry glass transition temperature while the fiber is under tension.

The invention relates to an electrospinning apparatus and method of use thereof.