A capsule shredding device is provided, which includes first and second housing sections. The first housing section has a chamber slightly larger than the capsule located in one end of the housing section so that when the capsule is seated in the chamber it cannot freely rotate in the chamber. A vial is releasably coupled to other end of the first housing section. One or more passageways extend from the bottom of the chamber toward the other end of the second housing section. The second housing section has an internal chamber with a spike extending into the chamber integrally formed on the interior upper section of the housing section. When the two housing sections are threaded together such that are drawn towards each other, the spike pierces the capsule, and upon further rotation the spike shreds the capsule thereby releasing the powder contained therein which flows through the one or more passageways into interior of the vial. Gaskets between the first and second housing sections and between the second housing section and the vial prevent powder or liquid in the vial escaping.

A dosing syringe including a hollow cylindrical body and a plunger slidable within the hollow cylindrical body. The dosing syringe includes at least one slider slidable within a distal flange of the hollow cylindrical body transversely to the hollow cylindrical body and at least one wall is formed in the plunger for abutting and blocking the slider during its sliding within the flange, wherein the at least one wall provides a mechanical stop which stops the stroke of the plunger at a predetermined volume of product to be aspirated and/or dispensed.

A sublingual type medication delivery device includes a container body having a predetermined volume of solvent with a spray dispenser attached at one end of the container and at the opposite end of the container is a housing which contains medication to be discharged into the container and mixed with the solvent to form a diluted medication for fractional delivery of the medication over a period of time. The housing can either be a tablet crusher for introducing medicament in solid form into the container or the housing can be a capsule having liquid medicament that is delivered through a needle that pierces the capsule wall.

Exemplary embodiments of the disclosure may be drawn to ingestible delivery devices. An ingestible delivery device may include a first compartment and a second compartment. A lipase may be contained within the first compartment, and a fat may be contained within the second compartment. The first compartment may be sealed from the second compartment prior to exposure to a trigger, preventing the lipase and the fat from contacting each other, and at least one of the first compartment or the second compartment may at least partially rupture upon exposure to the trigger, allowing the lipase and the fat to contact each other.

A high flow therapy system for delivering heated and humidified respiratory gas to an airway of a patient, the system including a respiratory gas flow pathway for delivering the respiratory gas to the airway of the patient by way of a non-sealing respiratory interface; wherein flow rate of the pressurized respiratory gas is controlled by a microprocessor.

The present invention provides methods of non-gastrointestinal transmucosal drug delivery that secures, sheaths, and protects vasoconstricting and or adrenergic drug from mixing with saliva and being swallowed, thereby preventing both decreased bioavailability and loss of efficacy, and ensuring restoration of proper blood perfusion. In preferred embodiments, the adrenergic drug is epinephrine and the method treats hypotension associated with anaphylaxis.

A device for dispensing active ingredient-containing or active ingredient-carrying strips, including a housing in which a coil chamber for receiving an active ingredient-containing or active ingredient-carrying band is arranged, in which a gear transmission with a driven roller for conveying the band is mounted, and in which a separating device for separating the strips from the band is arranged. A method for dispensing active ingredient-containing or active ingredient carrying strips using such a device is also disclosed. An active ingredient-containing or active ingredient-carrying band is arranged between the driven roller and the pressure roller. A shift clutch transmission having a manually actuatable trigger element is arranged upstream of the gear transmission. The driven roller can be driven in incremental strips by the shift clutch transmission. A device and method is disclosed for dispensing active ingredient-containing or active ingredient-carrying strips with a largely equal dosage are developed.

An oral gel composition suitable for the treatment of oral leukoplakia comprising a combination of diclofenac with hyaluronic acid and methods of administering the oral gel that may include a device that prolongs contact time of the oral gel with the areas of the mucosa that are affected by oral leukoplakia.

Compositions are provided for the liquid oral administration of topiramate and its salts. The invention further provides methods for treating diseases and disorders using the compositions.

A capsule for dosing a substance to be administered orally, comprising:—a dosing chamber (2) for the substance;—an access route (6) for access of the substance into the chamber (2);—a valve (3) which permits/prevents the supply of the substance to the dosing chamber (2) through the access route (6);—a connection means (4) for connecting to a mouth of a container.