An oral gel composition suitable for the treatment of oral leukoplakia comprising a combination of diclofenac with hyaluronic acid and methods of administering the oral gel that may include a device that prolongs contact time of the oral gel with the areas of the mucosa that are affected by oral leukoplakia.

A device for training users in a proper mixing of pharmaceutical components, or for aiding in the mixing, or for performing the mixing, and administration of pharmaceutical components is disclosed. The device comprises a housing for receiving a pharmaceutical delivery device containing the pharmaceutical components. There is also a microcontroller disposed in the housing and a motion/orientation detection device disposed within or on the housing and in communication with the microcontroller. A method for use of the device is also disclosed, along with a substance for use as one of the pharmaceutical components.

Embodiments of the present invention comprise an enteral syringe that, in a horizontal orientation, delivers more consistent nutrition throughout the feeding cycle by using a mixing disc that creates a path for milk from fat accumulating on top of the syringe's barrel to flow to the syringe's outlet, whereupon it is mixed into an emulsion. The distal face of the syringe's piston can be coated with, or made out of, a lipophobic material, which prevents fat accumulation, especially towards the end of the feeding cycle.

There is provided an apparatus for dispensing one or more drugs in pellet form. The apparatus includes a cartridge assembly configured to store drugs in pellet form, and dispense the drugs upon actuation of one or more dispensing mechanisms located within the cartridge assembly. The apparatus further includes a control unit configured to actuate the one or more dispensing mechanisms located within the cartridge assembly, as well as a cover including a collection region configured to receive and store drugs dispensed from the one or more dispensing mechanisms. The cover is movable between a first position in which the collection region of the cover forms an enclosed cavity, and a second position in which the collection region is exposed such that a user can access drugs contained therein.

A dosing syringe including a hollow cylindrical body and a plunger sliding within the hollow cylindrical body. The hollow cylindrical body includes a main body and a proximal end provided with an aperture. The main body has at least one portion having a cross-section smaller than that of the proximal end, whereby a surface is delimited between the main body and the proximal end, which is configured to abut against a corresponding surface of an adapter, so that the proximal end is removable and liquid-tight blocked between said surface of the adapter and a bottom wall provided with an aperture of the adapter, the aperture of the proximal end and the aperture of the bottom wall being in direct fluid communication therebetween. An adapter for use with a dosing syringe as defined above and an administration kit including the dosing syringe and the relative adapter are also provided.

There is described a device for dispensing a drug or medicament in pellet form. The device includes a cartridge including a chamber for containing a plurality of pellets and a screw pump, wherein the screw pump is configured to receive pellets from the chamber and, upon rotation of the screw pump, transport the pellets from the chamber to be dispensed from the device via the screw pump. The device further includes a rotating member extending through the cartridge and configured to rotate the screw pump so as to dispense pellets therefrom. The cartridge further includes a tapered portion configured to guide pellets contained within the chamber into the screw pump for dispensing from the device via the screw pump as aforesaid. The screw pump is located outside of the tapered portion of the cartridge.

Compositions comprising doses of NSAIDs less than 75 mg are provided. As shown herein, these compositions may be used for the treatment and prophylaxis of inflammatory conditions on the mucosa. In particular, acetyl salicylic acid at doses of less than 75 mg is shown to have therapeutic and prophylactic effect on the mucosa coupled without the adverse effects associated with NSAID administration.

The current pandemic due to Covid-19 stresses the importance of effectively treating highly contagious and deadly infections. The described medical device is meant to help the medical community by enabling them to treat patients more effectively. The delivery mechanism focuses on the mucous membrane. It is noninvasive and easy to use by patients directly. The device is hand-held, with incorporated germicidal UVC lights. It has two chambers connected by an internal application tip. The tip connects to a removable container which can be used with the prescribed treatment/therapy, vaccine, or viral testing fluid/reagent, as needed. Due to its versatility, non-invasive nature and germicidal properties, this device supports rapid response to infectious diseases, such as COVID-19. It may also further promote the development and use of different inoculation and drug techniques and delivery systems by enabling easy administration, via the mucous membrane.

The presently described technology provides a pill crushing system. The pill crushing system may comprise a tablet crusher, a bowl-like structure, and an elongated cylindrical weighted rod. The tablet crusher may have an open mouth, a lower end of the tablet crusher and a cap. The lower end of the tablet crusher may have a closed base provided with a peripheral thread along surface wall of the closed base. The cap may have a peripheral thread for engagement with the peripheral thread of the tablet crusher. The threaded arrangement for the tablet crusher and the cap are such as to bring the cap close to the closed base of the tablet crusher into engagement with the cap upon turning the cap in one direction, whereby a pill interposed therebetween may be crushed. The bowl-like structure may have smooth surfaces such that a residue after a pill is grounded in the bowl-like structure is less than 2 wt % of the pill. The elongated cylindrical weighted rod may have smooth surfaces at one end.

An apparatus for dispensing a solid oral dosage form is provided that includes one or more channels, each configured to store a plurality of units of the solid oral dosage form and having an outlet for dispensing the units therefrom. The apparatus further includes a rotatable shaft and a nut located on the shaft and configured to translate upon rotation of the shaft. The apparatus further includes one or more tines configured to translate with the nut. Each of the tine extends into a respective channel and is configured to push the units of the solid oral dosage form along the length of the respective channel to the outlet. Rotation of the shaft about its axis causes the units of the solid oral dosage form to be dispensed from the outlets of the channel(s) due to the translation of the one or more tines within the respective channel.