An electrospinning system, method, and apparatus comprises a dual polarity high voltage power supply with much less power out for safe operation, a solution dispensing assembly held at high positive potential by the dual polarity power supply, a Corona discharge assembly held at high negative potential by the dual polarity power supply, and a drum collector held at ground potential wherein a solution is drawn from the solution dispensing assembly to the drum collector thereby forming a fiber mat.

Described are fibrous materials comprising a plurality of fibers having a longitudinal alignment gradient and/or a longitudinal composition gradient. Also described are methods of preparing the fibrous materials thereof and methods of treating organ or tissue damage with the fibrous materials.

A multi-laminar electrospun nanofiber scaffold for use in repairing a defect in a tissue substrate is provided. The scaffold includes a first layer formed by a first plurality of electrospun polymeric fibers, and a second layer formed by a second plurality of electrospun polymeric fibers. The second layer is combined with the first layer. A first portion of the scaffold includes a higher density of fibers than a second portion of the scaffold, and the first portion has a higher tensile strength than the second portion. The scaffold is configured to degrade via hydrolysis after at least one of a predetermined time or an environmental condition. The scaffold is configured to be applied to the tissue substrate containing the defect, and is sufficiently flexible to facilitate application of the scaffold to uneven surfaces of the tissue substrate, and to enable movement of the scaffold by the tissue substrate.

An electrospinning system, method, and apparatus comprises a dual polarity high voltage power supply with much less power out for safe operation, a solution dispensing assembly held at high positive potential by the dual polarity power supply, a Corona discharge assembly held at high negative potential by the dual polarity power supply, and a drum collector held at ground potential wherein a solution is drawn from the solution dispensing assembly to the drum collector thereby forming a fiber mat.

The present invention relates to an apparatus for the mass production of polymeric nanofibres and their uniform deposition over any substrate. The present invention also provides a method for the manufacture of droplet free polymeric nanofibres by electrospinning process using multi-hole spinnerets. The droplet free polymeric nanofibres of the present invention are preferably of a diameter in the range of 50 nm to 850 nm.

A hyaluronic acid facial mask, a preparation method therefor and a use method therefor is provided. The facial mask includes a substrate layer, a hyaluronic acid layer and a protective paper layer sequentially arranged. The hyaluronic acid layer is made of hyaluronic acid nanofibers. The hyaluronic acid nanofibers are formed by spinning a hyaluronic acid composite using an electrospinning method. The hyaluronic acid composite includes a dispersed phase and a solvent phase. The dispersed phase includes, in terms of mass percentage content, 70-95% of hyaluronic acid. The solvent phase includes water. The preparation method includes: spinning the hyaluronic acid composite on the substrate layer using an electrospinning method to form a hyaluronic acid layer, and then attaching the protective paper layer on the hyaluronic acid layer.

A fiber collection tool for collecting a fiber spun by electrospinning is described. The fiber collection tool has a size holdable by the hand of a user, and includes, in its interior, an electroconductive section. Preferably, the fiber collection tool further includes a surface section outside the electroconductive section. In a fiber deposit production method, a user collects, with the fiber collection tool, a fiber spun by the user by performing electrospinning using an electrospinning device having a size holdable by the hand of the user, and thereby produces a film including a deposit of the fiber on a surface of the fiber collection tool. The fiber collection tool, having the deposit formed thereon, is pressed against a surface of an object, and the deposit is transferred onto the surface of the object, to form a film including the fiber deposit on the surface of the object.

An object is built by depositing a mat on a build surface and utilizing a manufacturing process to position a structure over at least a portion of the mat to define an object. The object is removed from the build surface such that a first portion of the mat removed with the object is bonded to the structure, and a second portion of the mat removed with the object is unsupported by the structure. Alternatively, an object can be built by printing a conductive material over a surface to define a structure and utilizing the conductive material as a collector to control an electric field deposition over the structure to define an object where a first portion of the deposition is bonded to the structure and a second portion of the deposition is unsupported by the structure.

The present invention relates to highly porous, bioresorbable electrospun sensors for optical detection of tissue oxygenation and processes of making and using same. Multiple sensor compositions are described that are focused on different applications/oxygen ranges. Such sensors alleviate the risk of leaving the sensor implanted in a subject, typically have as good or better oxygen sensing capabilities and comparable performance life span as non-degradable sensors and unlike sensors made from general bioresorbable materials maintain a desired porosity as they degrade. Thus, such sensors may remain integrated in a subject's body while they degrade and maintain the ability to sense oxygen for their performance life span.

A multi-laminar electrospun nanofiber scaffold for use in repairing a defect in a tissue substrate is provided. The scaffold includes a first layer formed by a first plurality of electrospun polymeric fibers, and a second layer formed by a second plurality of electrospun polymeric fibers. The second layer is combined with the first layer. A first portion of the scaffold includes a higher density of fibers than a second portion of the scaffold, and the first portion has a higher tensile strength than the second portion. The scaffold is configured to degrade via hydrolysis after at least one of a predetermined time or an environmental condition. The scaffold is configured to be applied to the tissue substrate containing the defect, and is sufficiently flexible to facilitate application of the scaffold to uneven surfaces of the tissue substrate, and to enable movement of the scaffold by the tissue substrate.