Disclosed are systems and methods for aseptically filling pharmaceutical containers with a pharmaceutical substance and then lyophilizing it. In one general aspect, the system and method can employ a lyophilizer loader subsystem having an interior chamber in communication with an interior chamber of a lyophilizer subsystem via a portal with a sealable door, with the collective interior being aseptically sealable. An articulated robotic arm can be employed to batch transfer to the lyophilizer subsystem container nests bearing the pharmaceutical containers. In one embodiment, the nests may be transferred serially to the loader subsystem, with the articulated robotic arm being configured to transfer the nests of containers in batches to the lyophilizer subsystem. The articulated robotic arm can also be configured to be used to move batches of nests within the lyophilizer subsystem. One implementation includes two articulated arms and a joint rotary wrist driven by two rotary shoulders.

A vessel includes an inner container, an outer container, a connector, a cap, and a lid. The outer container includes a first coupler and an outer chamber. The inner container includes a second coupler and an inner chamber to hold a liquid. The inner container is receivable at least partially within the outer chamber. The connector includes a third coupler that is complementary to the first coupler, and a fourth coupler that is complementary to the second coupler. When both the first coupler is engaged with the third coupler and the second coupler is engaged with the fourth coupler, the outer chamber is entirely enclosed within a liquid-proof barrier.

In one aspect, a thermoelectric anti-freeze block-based system includes a cartridge with a chemical battery comprising. The chemical battery for a gel material. The chemical battery uses the gel material to maintain an internal chamber of the cartridge at a specified temperature for a specified period of time, and the internal chamber of the cartridge, wherein the internal chamber comprises a sealable cylindrical cavity surrounded by the chemical battery. A vacuum-insulation thermos is provided that includes an internal chamber to hold the cartridge with the chemical battery. A charging station is provided that includes a thermoelectric anti-freeze block-based charging station includes a liquid pump. The liquid pump is connected through a bottom of the charging station where a thermoelectric cooler system is provided. The liquid pump comprises a radiator, a fan and an anti-freeze liquid material. The liquid pump circulates the anti-freeze liquid material inside the charging station and through the radiators. The circulated anti-freeze liquid material carries away the heat from a hot side of the thermoelectric cooler system. The cartridge with the chemical battery sits inside the charging station canister during the cooling process that cools the gel material within the chemical battery, and a power source that powers the liquid pump, the fan, and the radiator.

A supple carrier for carrying a container of medically useful solution or suspension. The supple carrier includes a first monitoring window providing a first visualization perspective of the container contained by the envelope and one or more adjustable pressurizers. The supple carrier can delay the temperature change of the medically useful solution or suspension carried by the carrier.

The present invention provides for a method of transporting and preparing an injectable ice slurry for administration to a patient at a point of care comprising preparing a biocompatible solution comprising water and at least one component other than water, placing the biocompatible solution into a container, transporting the container with the biocompatible solution to the point of care, transforming the biocompatible solution into an injectable ice slurry at the point of care, and administering the injectable ice slurry to the patient at the point of care.

The present invention provides for a method of transporting and preparing an injectable ice slurry for administration to a patient at a point of care comprising preparing a biocompatible solution comprising water and at least one component other than water, placing the biocompatible solution into a container, transporting the container with the biocompatible solution to the point of care, transforming the biocompatible solution into an injectable ice slurry at the point of care, and administering the injectable ice slurry to the patient at the point of care.

A portable preservation system comprising an outer container having at least one open end. An insulative layer wherein the insulative layer is placed in and coupled to the outer container. At least one supply line and at least one return line wherein at least one coil can be coupled between the supply line and the return line wherein the coil partially surrounds an inner container and a cap. The inner container can have at least one compartment. The insulative layer can be coupled between the coils and the outer container.

Disclosed are systems and methods for aseptically filling pharmaceutical containers with a pharmaceutical substance and then lyophilizing it. In one general aspect, the system and method can employ a lyophilizer loader subsystem having an interior chamber in communication with an interior chamber of a lyophilizer subsystem via a portal with a sealable door, with the collective interior being aseptically sealable. An articulated robotic arm can be employed to batch transfer to the lyophilizer subsystem container nests bearing the pharmaceutical containers. In one embodiment, the nests may be transferred serially to the loader subsystem, with the articulated robotic arm being configured to transfer the nests of containers in batches to the lyophilizer subsystem. The articulated robotic arm can also be configured to be used to move batches of nests within the lyophilizer subsystem. One implementation includes two articulated arms and a joint rotary wrist driven by two rotary shoulders.

A system and method of administering a freezable cough drop to a user. The system includes a quantity of medicated solution and a freezer. The medicated solution is an aqueous solution with medicinal and soothing properties and is portioned into a plurality of dosages. The method begins with the plurality of dosages being positioned within the freezer. At least one arbitrary dosage is removed from the freezer. Moreover, the arbitrary dosage is any one of the plurality of dosages. The arbitrary dosage is placed within a mouth of the user. The arbitrary dosage is dispensed from the mouth into a sore throat of the user by gradually dissolving the arbitrary dosage. The system further includes a blister pack with a plurality of blister compartments that houses the plurality of dosages. An arbitrary dosage is ejected out of the corresponding compartment before being placed within the mouth of the user.

A biological sample or drug stored inside a frozen storage container is not susceptible to contamination. The frozen storage container includes a container body with an internal space, and a partition wall which divides the internal space at least into a first space and a second space. In the container body, the first space is liquid-tightly sealed, the second space has an opening which is in communication with the outside, and the second space is liquid-tightly sealable by welding the container body. A frozen storage container system includes the frozen storage container; and a needle member which includes a needle tip portion capable of being inserted into the internal space of the container body and capable of piercing the partition wall, and has a flow path which is opened at the needle tip portion and is opened at a base end portion opposite to the needle tip portion.