Patent classifications
A61K6/56
Pulp regeneration compositions and methods of forming and using the same
A dental tissue regenerative composition. The composition includes a combination of (1) human dental pulp stem cells and (2) at least one of human umbilical vein endothelial cells or vascular endothelial growth factor. The combination is encapsulated in a light-activated gelatin methacrylate hydrogel.
Pulp regeneration compositions and methods of forming and using the same
A dental tissue regenerative composition. The composition includes a combination of (1) human dental pulp stem cells and (2) at least one of human umbilical vein endothelial cells or vascular endothelial growth factor. The combination is encapsulated in a light-activated gelatin methacrylate hydrogel.
Ceramic Bodies Having Antimicrobial Properties and Methods of Making the Same
A method for making a ceramic body comprised of a ceramic material having an inhibitory effect on bacterial growth is provided. A dental prosthesis may be made of a ceramic material that comprises a molybdenum-containing component on a portion of the prosthesis that contacts the gingival surface of a patient. In one method, a porous zirconia ceramic structure is shaped in the form of a dental prosthesis, and then infiltrated with a molybdenum-containing composition, before sintering to densify the ceramic structure.
Composition and method for using medicament for endodontic irrigation, stem cell preparation and tissue regeneration
A composition for tissue degradation and removal and disinfection is provided for dental and medical applications. It can function as a single intra-canal irrigant that eradicates microorganisms as it facilitates the debridement of a root canal system. It contains one or more hydoxides, a thioglycolate compound, sodium hypochlorite, sodium chloride, sodium chlorate, oxygen, and water, such as lime water and purified water, The thioglycolate compound is capable of degrading a cell by disrupting disulfide bonds in its proteins. The sodium hypochlorite enhances its function. The composition may also incorporate mineral oil, urea, cetearyl alcohol, D&C yellow No. 8, chromium hydroxide, theobroma cocoa seed butter, iron oxides, fragrances, lanolin, and/or ceteareth-20. It is effective against Enterococcus faecalis.
OBTURATION COMPOSITION
A dental composition comprising pre-reacted particulate mineral trioxide aggregate (MTA) dispersed in a hydrogel wherein the content of MTA in the composition is in the range of 20 to 50 percent by weight based on the total weight of the composition.
FLOWABLE COMPOSITION
A dental composition comprising a pre-reacted particulate mineral trioxide aggregate (MTA) dispersed in a polymer matrix wherein the content of MTA in the composition is in the range of 20 to 50 percent by weight based on the total weight of the composition.
Ceramic bodies having antimicrobial properties and methods of making the same
A method for making a ceramic body comprised of a ceramic material having an inhibitory effect on bacterial growth is provided. A dental prosthesis may be made of a ceramic material that comprises a molybdenum-containing component on a portion of the prosthesis that contacts the gingival surface of a patient. In one method, a porous zirconia ceramic structure is shaped in the form of a dental prosthesis, and then infiltrated with a molybdenum-containing composition, before sintering to densify the ceramic structure.
PULP REGENERATION COMPOSITIONS AND METHODS OF FORMING AND USING THE SAME
A dental tissue regenerative composition. The composition includes a combination of human dental pulp stem cells and at least one of human umbilical vein endothelial cells or vascular endothelial growth factor. The combination is encapsulated in a light-activated gelatin methacrylate hydrogel.
PULP REGENERATION COMPOSITIONS AND METHODS OF FORMING AND USING THE SAME
A dental tissue regenerative composition. The composition includes a combination of human dental pulp stem cells and at least one of human umbilical vein endothelial cells or vascular endothelial growth factor. The combination is encapsulated in a light-activated gelatin methacrylate hydrogel.
Root canal filling material containing mesenchymal stem cells and method for regenerating dental tissue using the same
A root canal filling material for a tooth extraction or tooth non-extraction process can be used clinically because of its easy availability and can efficiently enhance dental tissue regeneration; a method for regenerating dental tissue using the filling material is also provided. A root canal filling material 200 including mesenchymal stem cells 220 excluding dental pulp stem cells, which are inserted into the apical side of a root canal subjected to pulp extirpation or to root canal enlargement and cleaning of an infected root canal and including an extracellular matrix 210 is provided, and a method for regenerating dental tissue, through a tooth extracting or tooth non-extracting process, including a step of injecting the root canal filling material into the apical side of a root canal of a non-extracted tooth subjected to pulp extirpation or to root canal enlargement and cleaning of an infected root canal is provided.