A61K6/84

Separately packed curable composition
11744782 · 2023-09-05 · ·

Provided is a curable composition that has a sufficient pot life and does not cause a significant delay in curing time even after long-term storage at room temperature or higher. A separately packed curable composition includes: (A) a first pack containing: (a1) a polymerizable monomer having no acidic group, (b) a polymerizable monomer having an acidic group, and (c) a transition metal compound; and (B) a second pack containing: (a2) a polymerizable monomer having no acidic group, (d) an aromatic amine compound, and (e) at least one compound selected from sulfinic acid and a salt thereof.

Quick set cements for dental pulp capping and related methods of use

A dental pulp capping composition can comprise a particulate base material which is non-toxic, and capable of forming a structural capping matrix; and a particulate setting material which is non-toxic, water-soluble, biocompatible, and capable of setting the composition. Optional growth factors can also be introduced into the composition to facilitate dental tissue repair. A complimentary method of restoring damaged tooth features can comprise removing diseased and/or damaged portions of the tooth to expose a prepared tooth region. Water can be added to the dental pulp capping composition to form a workable coherent paste. The workable coherent paste can be introduced into the prepared tooth region. The workable coherent paste can then be shaped within the prepared tooth region and then set to form a rigid biomimetic structure within the prepared tooth region.

Quick set cements for dental pulp capping and related methods of use

A dental pulp capping composition can comprise a particulate base material which is non-toxic, and capable of forming a structural capping matrix; and a particulate setting material which is non-toxic, water-soluble, biocompatible, and capable of setting the composition. Optional growth factors can also be introduced into the composition to facilitate dental tissue repair. A complimentary method of restoring damaged tooth features can comprise removing diseased and/or damaged portions of the tooth to expose a prepared tooth region. Water can be added to the dental pulp capping composition to form a workable coherent paste. The workable coherent paste can be introduced into the prepared tooth region. The workable coherent paste can then be shaped within the prepared tooth region and then set to form a rigid biomimetic structure within the prepared tooth region.

Implant or medical tool made of a metal

The invention relates to an implant or medical tool made of a metal or having a surface made of a metal for use in a therapeutic treatment, wherein the implant or the tool has, on its/the surface, a coating with polycrystalline doped electrically conductive diamond, wherein the therapeutic therapy is a treatment of a microbial infection of a human or animal body, wherein the implant or the tool is connected as anode (12) in an electrochemical system in the body, wherein the electrochemical system comprises, in addition to the anode (12), a cathode (16), a power source connected in an electrically conductive manner to the anode and to the cathode, and an electrolyte comprising or consisting of a body fluid, or consists of the anode (12), a cathode (16), a power source connected in an electrically conductive manner to the anode and to the cathode, and an electrolyte comprising or consisting of a body fluid, or wherein the implant or the tool is disposed within an electrical field, by means of which a negative charge is induced at a first site and a positive charge at a second site by induction on the implant or tool, by means of which the first site becomes the anode (12) in an electrochemical system and the second site becomes the cathode (16) in the electrochemical system, wherein the electrochemical system comprises, in addition to the implant or the tool, an electrolyte comprising or consisting of a body fluid or consists of the implant or the tool and an electrolyte comprising or consisting of a body fluid.

Implant or medical tool made of a metal

The invention relates to an implant or medical tool made of a metal or having a surface made of a metal for use in a therapeutic treatment, wherein the implant or the tool has, on its/the surface, a coating with polycrystalline doped electrically conductive diamond, wherein the therapeutic therapy is a treatment of a microbial infection of a human or animal body, wherein the implant or the tool is connected as anode (12) in an electrochemical system in the body, wherein the electrochemical system comprises, in addition to the anode (12), a cathode (16), a power source connected in an electrically conductive manner to the anode and to the cathode, and an electrolyte comprising or consisting of a body fluid, or consists of the anode (12), a cathode (16), a power source connected in an electrically conductive manner to the anode and to the cathode, and an electrolyte comprising or consisting of a body fluid, or wherein the implant or the tool is disposed within an electrical field, by means of which a negative charge is induced at a first site and a positive charge at a second site by induction on the implant or tool, by means of which the first site becomes the anode (12) in an electrochemical system and the second site becomes the cathode (16) in the electrochemical system, wherein the electrochemical system comprises, in addition to the implant or the tool, an electrolyte comprising or consisting of a body fluid or consists of the implant or the tool and an electrolyte comprising or consisting of a body fluid.

Polyethylene-CNT-hydroxyapatite coated materials

A biocompatible polymer hybrid nanocomposite coating on a surface of a substrate, such as titanium and its alloys. The coating can be achieved by an electrostatic spray coating, preferably using ultra-high molecular weight polyethylene (UHMWPE) as a matrix for the coating. For example, up to 2.95 wt. % carbon nanotubes can be used as reinforcement, as can up to 4.95 wt. % hydroxyapatite. A dispersion of CNTs and HA in the coating is substantially uniform. The tribological performance of such coatings include high hardness, improved scratch resistance, excellent wear resistance, and corrosion resistance compared to pure UHMWPE coatings.

Polyethylene-CNT-hydroxyapatite coated materials

A biocompatible polymer hybrid nanocomposite coating on a surface of a substrate, such as titanium and its alloys. The coating can be achieved by an electrostatic spray coating, preferably using ultra-high molecular weight polyethylene (UHMWPE) as a matrix for the coating. For example, up to 2.95 wt. % carbon nanotubes can be used as reinforcement, as can up to 4.95 wt. % hydroxyapatite. A dispersion of CNTs and HA in the coating is substantially uniform. The tribological performance of such coatings include high hardness, improved scratch resistance, excellent wear resistance, and corrosion resistance compared to pure UHMWPE coatings.

Photocurable composition and dental restoration filling material

Provided is a photocurable composition that contains a polymerizable monomer (A), a spherical filler (B) having an average particle size within the range of 230-1000 nm, and a polymerization initiator (C), the photocurable composition being such that: 90% or more of the individual particles that constitute the spherical filler (B) are within a range of ±5% of the average particle size; the polymerizable monomer (A) and the spherical filler (B) satisfy condition (X1) represented by formula (1): nP<nF (where nP represents the refractive index at 25° C. of a polymer obtained by polymerizing the polymerizable monomer (A), and nF represents the refractive index at 25° C. of the spherical filler (B)); and the polymerization initiator (C) includes a photosensitizing compound (C1), a tertiary amine compound (C2), and a photoacid generator (C3).

Photocurable composition and dental restoration filling material

Provided is a photocurable composition that contains a polymerizable monomer (A), a spherical filler (B) having an average particle size within the range of 230-1000 nm, and a polymerization initiator (C), the photocurable composition being such that: 90% or more of the individual particles that constitute the spherical filler (B) are within a range of ±5% of the average particle size; the polymerizable monomer (A) and the spherical filler (B) satisfy condition (X1) represented by formula (1): nP<nF (where nP represents the refractive index at 25° C. of a polymer obtained by polymerizing the polymerizable monomer (A), and nF represents the refractive index at 25° C. of the spherical filler (B)); and the polymerization initiator (C) includes a photosensitizing compound (C1), a tertiary amine compound (C2), and a photoacid generator (C3).

MEDICAL CEMENT COMPOSITION
20220087907 · 2022-03-24 ·

The present disclosure relates to a medical cement composition containing calcium silicate in an amount of less than 20 wt % of a total weight of the composition, with a lithium salt being added thereto. The medical cement composition of the present disclosure has a low compressive strength of 12 MPa or less, after being hardened, for easy removal, excellent stability in storage, and high bioactivity.