Provided herein are methods for the controlled, independent modification of the surface of polymer-based materials and compositions generated thereby. The methods include use of low temperature plasma for surface modification. The methods allow for the alteration of multiple surface characteristics including generation of precise nanostructures, morphology, crystallography and chemical composition for increased biocompatibility, for example, hydrophilicity, steric hindrance, anti-inflammatory properties and/or anti-bacterial properties.

The invention relates to an implant or medical tool made of a metal or having a surface made of a metal for use in a therapeutic treatment, wherein the implant or the tool has, on its/the surface, a coating with polycrystalline doped electrically conductive diamond, wherein the therapeutic therapy is a treatment of a microbial infection of a human or animal body, wherein the implant or the tool is connected as anode (12) in an electrochemical system in the body, wherein the electrochemical system comprises, in addition to the anode (12), a cathode (16), a power source connected in an electrically conductive manner to the anode and to the cathode, and an electrolyte comprising or consisting of a body fluid, or consists of the anode (12), a cathode (16), a power source connected in an electrically conductive manner to the anode and to the cathode, and an electrolyte comprising or consisting of a body fluid, or wherein the implant or the tool is disposed within an electrical field, by means of which a negative charge is induced at a first site and a positive charge at a second site by induction on the implant or tool, by means of which the first site becomes the anode (12) in an electrochemical system and the second site becomes the cathode (16) in the electrochemical system, wherein the electrochemical system comprises, in addition to the implant or the tool, an electrolyte comprising or consisting of a body fluid or consists of the implant or the tool and an electrolyte comprising or consisting of a body fluid.

The invention relates to an implant or medical tool made of a metal or having a surface made of a metal for use in a therapeutic treatment, wherein the implant or the tool has, on its/the surface, a coating with polycrystalline doped electrically conductive diamond, wherein the therapeutic therapy is a treatment of a microbial infection of a human or animal body, wherein the implant or the tool is connected as anode (12) in an electrochemical system in the body, wherein the electrochemical system comprises, in addition to the anode (12), a cathode (16), a power source connected in an electrically conductive manner to the anode and to the cathode, and an electrolyte comprising or consisting of a body fluid, or consists of the anode (12), a cathode (16), a power source connected in an electrically conductive manner to the anode and to the cathode, and an electrolyte comprising or consisting of a body fluid, or wherein the implant or the tool is disposed within an electrical field, by means of which a negative charge is induced at a first site and a positive charge at a second site by induction on the implant or tool, by means of which the first site becomes the anode (12) in an electrochemical system and the second site becomes the cathode (16) in the electrochemical system, wherein the electrochemical system comprises, in addition to the implant or the tool, an electrolyte comprising or consisting of a body fluid or consists of the implant or the tool and an electrolyte comprising or consisting of a body fluid.

This invention relates to antimicrobial gallium compounds, and to monomers containing gallium complex moieties that can be used in oral care products and dental materials, and which can reduce or eliminate dental caries and bacterial or fungal infections associated with medical and dental devices.

This invention relates to antimicrobial gallium compounds, and to monomers containing gallium complex moieties that can be used in oral care products and dental materials, and which can reduce or eliminate dental caries and bacterial or fungal infections associated with medical and dental devices.

A dental resin composite material is provided that is reduced in darkness of its color tone, and also reduced in burning and color unevenness. Specifically provided are a dental resin composite material including 100 parts by mass of a polyaryletherketone resin, 10 parts by mass to 300 parts by mass of inorganic particles, and 90 ppm or less of an impurity having an aromatic ring, a method of producing the dental resin composite material, and a polyaryletherketone resin for producing a dental resin composite material, to be used for producing the dental resin composite material.

A dental resin composite material is provided that is reduced in darkness of its color tone, and also reduced in burning and color unevenness. Specifically provided are a dental resin composite material including 100 parts by mass of a polyaryletherketone resin, 10 parts by mass to 300 parts by mass of inorganic particles, and 90 ppm or less of an impurity having an aromatic ring, a method of producing the dental resin composite material, and a polyaryletherketone resin for producing a dental resin composite material, to be used for producing the dental resin composite material.

Disclosed is an implanted device, comprising a device base body and an active drug, wherein the device base body is pure zinc and/or a zinc alloy, the zinc content in the device base body is 0.1-100%, and the active drug comprises anti-allergic drugs. After the implantation of the implanted device into the human body, the surrounding tissues of the implant would not have a clear hypersensitive reaction due to the presence of the anti-allergic drugs, and the implanted device can be used to be implanted into the body for supporting organ chambers, to fill the hollow chambers of the organs and tissues or as orthopaedic implants etc.

Disclosed is an implanted device, comprising a device base body and an active drug, wherein the device base body is pure zinc and/or a zinc alloy, the zinc content in the device base body is 0.1-100%, and the active drug comprises anti-allergic drugs. After the implantation of the implanted device into the human body, the surrounding tissues of the implant would not have a clear hypersensitive reaction due to the presence of the anti-allergic drugs, and the implanted device can be used to be implanted into the body for supporting organ chambers, to fill the hollow chambers of the organs and tissues or as orthopaedic implants etc.

A polymerisable dental composite material comprising (i) 70 to 85% by weight of an inorganic filler component comprising at least one dental glass and optionally at least one amorphous metal oxide, (ii) 10 to 30% by weight of at least one monomer comprising 1,3-bis(5-alkyl-3,8-dioxo-2-aza-4,7-dioxa-decyl-9-en)phenyl and/or 1,3-bis(5,9-dialkyl-3,8-dioxo-2-aza-4,7-dioxa-decyl-9-en)phenyl, (iii) 0.01 to 5% by weight of at least one di-, tri-, tetra- or multi-functional monomer not being a urethane (meth)acrylate, (iv) 0.01 to 10% by weight of at least one initiator, of an initiator system and optionally of at least one stabilizer and optionally of at least one pigment, wherein the total composition of the composite material amounts to 100% by weight, and a polymerized composite material having a flexural strength of greater than or equal to 190 MPa and an elastic modulus of 12 to 21 GPa for the production of indirect dentures.