A method for improving the appearance of the skin, moisturizing skin and/or providing an antioxidant effect to skin by administering to skin a composition comprising an effective amount of a hydrogen-generating agent or molecular hydrogen and a carrier having a phosphatidylcholine component entrapping the hydrogen-generating agent or molecular hydrogen. A skin care product has an effective amount of molecular hydrogen and/or a hydrogen-generating agent; and a carrier entrapping them. Desirably, the composition is an aqueous base, and the hydrogen-generating agent and the carrier form a first phase of the composition, and an emulsifier forms a second phase of the composition.

A stable, multiphase liquid isotropic cleansing composition is described that contains high levels of Petrolatum and shows a substantial decrease in reflectance compared with isotropic cleansing compositions containing other oils and liquid crystalline compositions with similar levels of oils. The inventive composition has a total of less than 2% by wt. of other oils such as glyceride, mineral and silicone oils, or blends thereof.

The present invention relates to compositions forming a low viscosity mixture of: a) at least one diacyl glycerol; b) at least one phosphatidyl choline; c) at least one oxygen containing organic solvent; d) at least one GnRH analogue;
wherein the pre-formulation forms, or is capable of forming, at least one liquid crystalline phase structure upon contact with an aqueous fluid. The invention further relates to methods of treatment comprising administration of such compositions, pre-filled administration devices and kits containing the formulations.

A cosmetic product is described which in addition to water, contains at least one hydrogenated phospholipid in a concentration of at least 0.7% by weight, at least one divalent and/or trivalent alcohol, and at least one wax. In the cosmetic product, the weight ratio of hydrogenated phospholipid to the wax varies between 1:0.3 and 1:1.5, more preferably between 1:0.7 and 1:1, wherein the hydrogenated phospholipid is at least partially present in an ortho-rhombic lamellar crystalline structure and the wax is incorporated in the ortho-rhombic lamellar crystalline structure and/or is attached to the ortho-rhombic lamellar crystalline structure.

The present invention generally relates to compositions and methods for transdermal delivery, treatment of skin, and improving the appearance of skin. In some cases, the composition may include nitric oxide and/or peptides. The nitric oxide and/or peptide may be present within a first phase comprising a lecithin, such as phosphatidylcholine. In certain embodiments, the lecithin is present in liposomes, micelles, or other vesicles containing nitric oxide, peptides, or both. The composition can take the form of a gel, a cream, a lotion, an ointment, a solution, a solid stick, etc., that can be rubbed or sprayed onto the skin. Other aspects of the present invention are generally directed to methods of making or using such compositions, methods of promoting such compositions, kits including such compositions, or the like.

Personal care compositions having at least a cleansing phase and a benefit phase. The cleansing phase includes a surfactant A or a surfactant B. The surfactant A includes a C13 alkyl sulfate anionic surfactant. The surfactant B has a mixture of C12 and C13 alkyl sulfate anionic surfactants. The cleansing phase also includes a zwitterionic surfactant. The zwitterionic surfactant includes an hydroxysultaine. The cleansing phase has a structuring system having: optionally a non-ionic emulsifier; optionally a rheology modifier; and from about 3% to about 10% by weight of the personal care composition, of an electrolyte. The benefit phase includes a benefit agent.

The present disclosure is drawn to cleansing compositions. The cleansing compositions include: (a) one or more anionic surfactants; (b) one or more nonionic emulsifiers having a Hydrophile-Lipophile Balance (HLB) of about 6 or less; (c) one or more salts providing divalent cations having a charge density of about 40 to about 200 C/mm.sup.3 and a water solubility of at least 400 g/L; (d) one or more anionic polymers; (e) one or more water soluble solvents; and (f) water. The cleansing compositions have a unique lamellar liquid crystal structure and are useful in methods for cleansing the body, including the skin and hair.

The present disclosure provides a chlorhexidine-cyclamate complex having a formula [C.sub.22H.sub.32Cl.sub.2N.sub.10][C.sub.6H.sub.12NO.sub.3S].sub.2 having antibacterial and antiplaque properties, together with oral care compositions comprising the complex, and methods of making and using these complexes and compositions.

An aqueous shear-thinning personal care composition comprises: (a) at least 3 wt % of a sulfonate compound of general formula (I): where R.sup.1 represents a C.sub.8-22 alkyl group alkyl group; R.sup.2 represents a C.sub.1-4 alkyl group; each of R.sup.3, R.sup.4 and R.sup.5 independently represents a hydrogen atom or a C.sub.1-4 alkyl group; and M.sup.+ represents a sodium or potassium cation; (b) at least 3 wt % of an amphoteric or zwitterionic surfactant; (c) at least 10 wt % of water; and (d) at least 0.5 wt % of an additional component in the form of particles or droplets suspended in the composition. The composition is stable in an aqueous environment and can be formulated with a wide range of additional components.

A personal care composition comprising: at least a first phase and a second phase wherein said first phase comprises a) an aqueous structured surfactant phase comprising STnS where n is between about 0 and about 2.5; b); c) a structuring system comprising i. optionally, a non-ionic emulsifier; ii. optionally, from about 0.05% to about 5%, by weight of said personal care composition, of an associative polymer; iii. an electrolyte; and said second phase comprises a) a benefit phase comprising from 1% to about 50%, by weight of said personal care composition, of a hydrophobic benefit agent.