A61K8/0295

Method of use and compositions

The present invention is directed to a method for improving the occlusiveness of a topical pharmaceutical or cosmetic formulation in use in a patient in need thereof, comprising adding to the formulation at least 0.1- to about 10% w/w of one or more of a monofatty acid ester of glycerin and/or one or more of a monofatty acid ester of glycol, or mixtures thereof. The present invention is also directed to a method for maintaining skin barrier efficiency of the stratum corneum of a patient in need thereof, comprising applying to the skin of said patient a pharmaceutical or cosmetic formulation containing at least 3% w/w of one or more of a monofatty acid ester of glycerin and/or one or more of a monofatty acid ester of glycol, or mixtures thereof.

DMS (derma membrane structure) in Foam Creams
20220110842 · 2022-04-14 ·

The invention relates to a foam formulation comprising an emulsion, comprising an oil phase and a water phase, the oil phase comprising at least one membrane-forming substance forming a lamellar membrane in the foam formulation.

Chlorhexidine-cyclamate complexes and oral care compositions comprising the same

The present disclosure provides a chlorhexidine-cyclamate complex having a formula [C.sub.22H.sub.32Cl.sub.2N.sub.10][C.sub.6H.sub.12NO.sub.3S].sub.2 having antibacterial and antiplaque properties, together with oral care compositions comprising the complex, and methods of making and using these complexes and compositions.

COSMETIC COMPOSITION OF LIQUID CRYSTAL LIPID PARTICLES FOR PERSONAL CARE APPLICATIONS
20220096337 · 2022-03-31 ·

The presently claimed invention relates to liquid crystal lipid particles. The presently claimed invention relates to liquid crystal lipid particles which are used in topical composition which has high moisturization efficacy, excellent skin feel, skin softness, and skin smoothness benefits.

EXTERNAL PREPARATION COMPRISING NON-LAMELLAR LIQUID CRYSTAL-FORMING LIPID

The present invention relates to an external preparation that is well retained on a living body surface and is capable of increasing drug permeability, in particular, an external preparation comprising a non-lamellar liquid crystal-forming lipid and a drug.

Liquid Crystal Hair Dye Composition, Use and Method

A temporary liquid crystal hair colour composition for temporarily colouring hair, particularly, non-lightened, unbleached or dark hair is provided. The colour composition contains an encapsulated liquid crystal and a coating composition comprising a thickening agent and a rheology modifier and the hair retains a natural feel while exhibiting a vibrant colour effect.

ENHANCED MOISTURIZER DEPOSITION IN CLEANSING LIQUIDS CONTAINING HYDROPHOBICALLY OR NON-HYDROPHOBICALLY MODIFIED ANIONIC POLYMERS

The invention relates to compositions comprising hydrophobically and non-hydrophobially modified cross-linked anionic polymers which have been found to minimally hinder deposition of moisturizers in compositions comprising cationic deposition polymers.

LIPID DEPOT FORMULATIONS

The present invention relates to pre-formulations comprising low viscosity, non-liquid crystalline, mixtures of: a) at least one neutral diacyl lipid and/or at least one tocopherol; b) at least one phospholipid; c) at least one biocompatible, oxygen containing, low viscosity organic solvent;
wherein at least one bioactive agent is dissolved or dispersed in the low viscosity mixture and wherein the pre-formulation forms, or is capable of forming, at least one liquid crystalline phase structure upon contact with an aqueous fluid. The preformulations are suitable for generating parenteral, non-parenteral and topical depot compositions for sustained release of active agents. The invention additionally relates to a method of delivery of an active agent comprising administration of a preformulation of the invention, a method of treatment comprising administration of a preformulation of the invention and the use of a preformulation of the invention in a method for the manufacture of a medicament.

PROCESS FOR THE PREPARATION OF A BASE FORMULATION FOR A DERMATOLOGICAL SUNSCREEN COMPOSITION AND FOR THE PREPARATION OF A DERMATOLOGICAL SUNSCREEN COMPOSITION
20210093519 · 2021-04-01 ·

A process for preparing a base formulation for a dermatological sunscreen composition comprising base formulations comprising oil and water phases and containing a plurality of UV-absorbing substances and at least one amphiphilic substance which forms lamellar structures.

Skin mimicking emulsion
10966914 · 2021-04-06 · ·

The present invention is directed to a skin-mimicking emulsion comprised of polyosides, minerals, inositol polyphosphate or phytic acid, polysaccharides, triglycerides, polyols, alpha or beta hydroxy acids, phospholipids, phytosterols, vitamins, fatty alcohols, essential lipids, amino acids, and water. All of the inventive ingredients in combination are design to be similar to those found in skin and are combined to form a lamellar structure for maximum efficacy. The composition does not include any of the components usually found in conventional emulsions, such as synthetic preservatives, surfactants, fragrances, colorants, acrylic polymers, gelling agents, sequestrants, and EDTA as such ingredients would be irritating to the skin.