A61K9/7015

Lipoleosomes as carriers for aromatic amide anesthetic compounds
10596117 · 2020-03-24 ·

The present invention provides a water continuous dispersion of nanoparticles. The water continuous dispersion includes: one or more aromatic amide anesthetic compounds; one or more polyethoxylated high HLB surfactants; one or more low HLB surfactants; one or more oils, wherein one or more nanoparticles of a dispersed phase include a lipid bilayer, and wherein ratio of oil to surfactant is between about 0.12:1 to about 3.5:1. Methods of preparing various water continuous dispersion of nanoparticles are also provided.

Topical formulations comprising a steroid

The application provides formulations for the topical administration of an active agent comprising at least one steroid, in the form of topical sprays that are propellant-free, and/or substantially non-foaming, and/or alcohol-free. The present application also provides processes for preparing such compositions and methods of using them in management of skin diseases or disorders such as psoriasis, dermatoses, and other associated skin diseases or disorders.

THERAPEUTIC AGENT FOR ONYCHOMYCOSIS

It is an object of the present invention to provide an efinaconazole-containing film-forming preparation, which has no sticky surface after solidification thereof, has sufficient cohesiveness after solidification thereof, and is easily peeled without washing. The present invention provides a therapeutic preparation for onychomycosis, comprising efinaconazole or a salt thereof, 1% by weight or more and 30% by weight or less of ethyl cellulose, 20% by weight or more of a volatile solvent (wherein the volatile solvent is water or a liquid component having a boiling point lower than that of water), and 0.01% by weight or more and less than 30% by weight of a surfactant.

Composition comprising bacteriophages for reducing, eliminating and/or preventing Salmonella enteritidis, Salmonella typhimurium and Salmonella paratyphi B

The present invention relates to a new cocktail of bacteriophages with specific lytic activity against Salmonella enteritidis, Salmonella typhimurium and Salmonella paratyphi B., for reducing, eliminating and/or preventing them in farm animals and animals from the poultry sector, such as poultry, hens and breeding hens, in addition to eggs. It may be administered as an additive in the feed, in water or by spray. Moreover, the cocktail may be used as a disinfectant in work areas of farms and abattoirs, and in processed foods, without affecting the organoleptic properties of the product.

Polymer

The present application relates to a polymer, a method for preparing the same, and a use thereof. The present application provides a polymer, a method for preparing the same, and a use thereof. The present application can provide: a polymer, which has a composition for allowing a low solubility in polar and non-polar solvents and can be prepared in a simple polymerization manner, such as solution polymerization; and a use thereof.

PEELABLE NAIL LACQUER
20200030249 · 2020-01-30 ·

The present invention provides a liquid composition comprising a pharmaceutically active compound and an aqueous polymer dispersion, wherein said liquid composition forms a film upon drying under standard ambient temperature and pressure; a method for providing the same; and a container comprising said liquid composition.

METHOD FOR REDUCING ITCHING IN ATOPIC DERMATITIS
20200016122 · 2020-01-16 · ·

This invention relates to a method for treating atopic dermatitis, comprising administering an effective amount of N-acyltryptamine represented by Formula (I):

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wherein R represents a saturated aliphatic hydrocarbon group having 2 to 29 carbon atoms; or a pharmaceutically acceptable salt, hydrate or solvate thereof to a subject in need thereof.

Compositions and Methods for Treatment of Infections
20200009253 · 2020-01-09 ·

This invention relates to the field of topical treatments for infections such as nail infections, particularly fungal infections of the nail commonly referred to as onychomycosis. Particularly, the invention relates to novel compositions containing peroxide for the treatment of such nail infections and other infections.

COMPOSITIONS AND METHODS FOR APPLICATION OVER SKIN

Disclosed herein are compositions that can form a covering, layer, film, device, and/or prosthetic skin that can be comfortably worn to provide skin barrier function, skin hydration and therapeutic and aesthetic benefits. The present invention provides novel compositions that have low tackiness and form quickly, resulting in a wearable, comfortable (maintains temperature and humidity), breathable, thin, optically invisible, cosmetically elegant, flexible, stretchable, elastic and body-movement conforming, yet long-lasting covering, layer, film, device, and/or prosthetic skin on the skin or any other body surface. The present invention provides novel compositions that can form a covering, layer, film, device, and/or prosthetic skin that works for extended periods in excess of about 24 hours, while retaining function during and after exercising, showering and swimming (in sea-water, fresh water and chlorinated water), steam room (heat at high humidity), and sauna (heat at low humidity).

Antifungal composition
10525003 · 2020-01-07 · ·

The invention provides a topical liquid antifungal composition containing an antifungal agent, a film-forming agent and a solvent. The composition is applied on the infected skin area to form a film that delivers the active agent. The invention also provides a method for treating a fungal infection on the skin by applying the topical antifungal composition that forms a film on the skin.