Compositions for the treatment of some orphan diseases and oral mucosal ulcers, many with similarities in terms of their anti-inflammatory and anti-oxidative activities, but also multiple differences in their observed abilities that can be combined to challenge the current, underlying pathophysiology. The orphan diseases of interest are Dupuytren's Contracture, Peyronie's Disease, Scleroderma, Raynaud's (or Renaud's) Phenomenon, chemotherapy/radiation induced oral mucosal ulceration, and aphthous ulcers; and more frequent skin issues of skin damage from cuts, abrasions, and burns; aging skin changes, and toe nail fungus. These can be treated with the disclosed compositions with the proper combination and alteration of ingredients inclusive of alpha-pinene, an aloe vera preparation, and a shea butter preparation. A process for preparation of such ingredients in a water-in-oil emulsion is described herein.

Compositions for the treatment of some orphan diseases and oral mucosal ulcers, many with similarities in terms of their anti-inflammatory and anti-oxidative activities, but also multiple differences in their observed abilities that can be combined to challenge the current, underlying pathophysiology. The orphan diseases of interest are Dupuytren's Contracture, Peyronie's Disease, Scleroderma, Raynaud's (or Renaud's) Phenomenon, chemotherapy/radiation induced oral mucosal ulceration, and aphthous ulcers; and more frequent skin issues of skin damage from cuts, abrasions, and burns; aging skin changes, and toe nail fungus. These can be treated with the disclosed compositions with the proper combination and alteration of ingredients inclusive of alpha-pinene, an aloe vera preparation, and a shea butter preparation. A process for preparation of such ingredients in a water-in-oil emulsion is described herein.

Disclosed herein are prenatal dosage forms formulated for different stages of the pregnancy cycle. Also disclosed are methods of administering prenatal dosage forms to a prenatal, pregnant or lactating woman. Further disclosed are kits including prenatal dosage forms.

Disclosed herein are prenatal dosage forms formulated for different stages of the pregnancy cycle. Also disclosed are methods of administering prenatal dosage forms to a prenatal, pregnant or lactating woman. Further disclosed are kits including prenatal dosage forms.

Compositions including plant-derived components, optionally administered with CBD, an amount of one or both of magnolol and honokiol effective to provide an antiangiogenic or anti-inflammatory effect that may be useful for reducing cortisol levels and treating a variety of ailments. Furthermore, methods of antiangiogenic or anti-inflammatory and reducing cortisol levels in a human. Plant-derived components of such compositions include magnolol and honokiol as extracts or compounds, or tinctures or solutions and may also include Ashwagandha and/or Magnolia Bark. The compositions may also include other therapeutic compounds such hydroxytyrosol (such as that in olive oil), phospholipids, and carotenoids. The present invention includes methods of treatment of various ailments including anxiety, depression, post-traumatic stress disorder (“PTSD”), stress, insomnia, and drug addiction. The methods may also be used to reduce body weight and/or enhance alertness and focus.

Compositions including plant-derived components, optionally administered with CBD, an amount of one or both of magnolol and honokiol effective to provide an antiangiogenic or anti-inflammatory effect that may be useful for reducing cortisol levels and treating a variety of ailments. Furthermore, methods of antiangiogenic or anti-inflammatory and reducing cortisol levels in a human. Plant-derived components of such compositions include magnolol and honokiol as extracts or compounds, or tinctures or solutions and may also include Ashwagandha and/or Magnolia Bark. The compositions may also include other therapeutic compounds such hydroxytyrosol (such as that in olive oil), phospholipids, and carotenoids. The present invention includes methods of treatment of various ailments including anxiety, depression, post-traumatic stress disorder (“PTSD”), stress, insomnia, and drug addiction. The methods may also be used to reduce body weight and/or enhance alertness and focus.

Disclosed are compositions comprising beta-caryophyllene (BCP) for use in the treatment of schizophrenia, methods of making such compositions and methods of treating schizophrenia using BCP. Disclosed are also compositions comprising CB2 receptor agonists for use in the treatment of schizophrenia, methods of making such compositions and methods of treating schizophrenia using CB2 receptor agonists.

Disclosed are compositions comprising beta-caryophyllene (BCP) for use in the treatment of schizophrenia, methods of making such compositions and methods of treating schizophrenia using BCP. Disclosed are also compositions comprising CB2 receptor agonists for use in the treatment of schizophrenia, methods of making such compositions and methods of treating schizophrenia using CB2 receptor agonists.

Disclosed are compositions comprising beta-caryophyllene (BCP) for use in the treatment of schizophrenia, methods of making such compositions and methods of treating schizophrenia using BCP. Disclosed are also compositions comprising CB2 receptor agonists for use in the treatment of schizophrenia, methods of making such compositions and methods of treating schizophrenia using CB2 receptor agonists.

The invention relates to pharmaceutical compositions comprising Δ9-tetrahydrocannabinol (THC), cannabidiol (CBD) and cannabigerol (CBG) and a terpene component, and their use in the treatment of chronic pain. The invention also relates to methods for treating chronic pain, especially chronic pain in athletes.