Disclosed in certain embodiments is a method of treating long-haulers syndrome associated with infection (e.g., Covid-19) comprising administering a therapeutically effective amount of niclosamide or a pharmaceutically acceptable salt thereof to a patient in need thereof.

The present invention relates to halogenated salicylanilides for use in the treatment of dermatitis in a human subject, for example atopic dermatitis in a human subject.

The present invention relates to halogenated salicylanilides for use in the treatment of dermatitis in a human subject, for example atopic dermatitis in a human subject.

The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosamide and derivatives thereof including salts, hydrates, esters and the like for use in the topical treatment or prevention of infections caused by Gram-positive bacteria such as Staphylococcus, in particular Staphylococcus aureus, and Streptococcus, in particular Streptococcus pyogenes. Gram positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appearance of resistant mutants compared to commonly used topical antibiotics.

The invention relates to a halogenated salicylanilide selected from closantel, rafoxanide, oxyclozanide and niclosamide and derivatives thereof including salts, hydrates, esters and the like for use in the topical treatment or prevention of infections caused by Gram-positive bacteria such as Staphylococcus, in particular Staphylococcus aureus, and Streptococcus, in particular Streptococcus pyogenes. Gram positive bacteria treated with the halogenated salicylanilides exhibit a very low frequency of appearance of resistant mutants compared to commonly used topical antibiotics.

The present invention relates to halogenated salicylanilides for use in the treatment of dermatitis in a non-human subject, for example canine or feline atopic dermatitis.

The present invention relates to halogenated salicylanilides for use in the treatment of dermatitis in a non-human subject, for example canine or feline atopic dermatitis.

The invention relates to a halogenated salicylanilide selected from niclosamide and oxyclozanide, or a pharmaceutically acceptable salt or hydrate thereof, for use in topical anti-inflammatory treatment of one or more clinical signs or symptoms of an inflammatory skin condition in a subject, wherein the one or more clinical signs or symptoms are associated with an abnormal inflammatory response, and the topical anti-inflammatory treatment modulates expression in lesional skin of one or more immune effectors selected from proinflammatory mediators and skin barrier molecules.

Nonhormonal unisex contraceptive products, compositions, formulations and methods of use comprise an effective amount of a targeted mild mitochondria uncoupler.

The present invention relates to a new topical composition comprising niclosamide and/or oxyclozanide and to the use of said composition for the treatment or prevention of pyoderma or dermatitis in non-human mammals.