A61K31/7135

Pharmaceutical Combination for the Treatment of Cancer

The present invention relates to a pharmaceutical combination comprising a CDK inhibitor and at least one antioxidant enzyme inhibitor for use in the treatment of cancer. The present invention also relates to a method for the treatment of cancer comprising administering to a subject in need thereof, a therapeutically effective amount of a CDK inhibitor and a therapeutically effective amount of at least one antioxidant enzyme inhibitor. The pharmaceutical combination of the present invention exhibits synergistic effect when used in the treatment of cancer.

Methods and compositions for administration of iron

The present invention generally relates to treatment of iron-related conditions with iron carbohydrate complexes. One aspect of the invention is a method of treatment of iron-related conditions with a single unit dosage of at least about 0.6 grams of elemental iron via an iron carbohydrate complex. The method generally employs iron carbohydrate complexes with nearly neutral pH, physiological osmolarity, and stable and non-immunogenic carbohydrate components so as to rapidly administer high single unit doses of iron intravenously to patients in need thereof.

Methods and compositions for administration of iron

The present invention generally relates to treatment of iron-related conditions with iron carbohydrate complexes. One aspect of the invention is a method of treatment of iron-related conditions with a single unit dosage of at least about 0.6 grams of elemental iron via an iron carbohydrate complex. The method generally employs iron carbohydrate complexes with nearly neutral pH, physiological osmolarity, and stable and non-immunogenic carbohydrate components so as to rapidly administer high single unit doses of iron intravenously to patients in need thereof.

ANTIVIRAL USE OF LIRAGLUTIDE AND GEFITINIB
20230270826 · 2023-08-31 ·

The present invention refers to a pharmaceutical preparation comprising liraglutide or gefitinib or a salt, solvate or combination thereof, in an effective amount for use in prophylactic or therapeutic treatment of a disease condition which is caused by or associated with an infection by a coronavirus.

ANTIVIRAL USE OF LIRAGLUTIDE AND GEFITINIB
20230270826 · 2023-08-31 ·

The present invention refers to a pharmaceutical preparation comprising liraglutide or gefitinib or a salt, solvate or combination thereof, in an effective amount for use in prophylactic or therapeutic treatment of a disease condition which is caused by or associated with an infection by a coronavirus.

ANTIVIRAL USE OF LIRAGLUTIDE AND GEFITINIB
20230270826 · 2023-08-31 ·

The present invention refers to a pharmaceutical preparation comprising liraglutide or gefitinib or a salt, solvate or combination thereof, in an effective amount for use in prophylactic or therapeutic treatment of a disease condition which is caused by or associated with an infection by a coronavirus.

BILIRUBIN-COATED RADIO-LUMINESCENT PARTICLES

The present disclosure relates to novel compositions comprising hydrophilic polymer-conjugated bilirubin-coated radio-luminescent particle or particle aggregates, and methods to make and use the novel compositions. A specific novel PEG-BR/CWO NP system provided in this disclosure comprises a CaWO.sub.4 nanoparticle (CWO NP) core encapsulated by a poly(ethylene glycol)-bilirubin conjugate micelle (PEG-BR micelle).

THERAPEUTIC COMPOSITION AND METHOD FOR TREATING CORONAVIRUS INFECTION

Provided is a therapeutic composition for treatment of coronavirus infection. The therapeutic composition contains a gold compound that generates Au—S bonds at the active pockets of the main protease of the virus while suppressing the virus-induced inflammations in the body.

THERAPEUTIC COMPOSITION AND METHOD FOR TREATING CORONAVIRUS INFECTION

Provided is a therapeutic composition for treatment of coronavirus infection. The therapeutic composition contains a gold compound that generates Au—S bonds at the active pockets of the main protease of the virus while suppressing the virus-induced inflammations in the body.

THERAPEUTIC COMPOSITION AND METHOD FOR TREATING CORONAVIRUS INFECTION

Provided is a therapeutic composition for treatment of coronavirus infection. The therapeutic composition contains a gold compound that generates Au—S bonds at the active pockets of the main protease of the virus while suppressing the virus-induced inflammations in the body.