A61K38/55

METHODS AND COMPOSITIONS USING SERPIN PRODUCING BACTERIA

Serpin protein producing Bifidobacterium longum subsp. longum and compositions thereof for use in inhibiting gluten digestion. Compositions comprising the serpin protein producing Bifidobacterium longum subsp. longum may be used to mitigate the effects of hidden gluten in individuals following a gluten free diet.

METHODS AND COMPOSITIONS USING SERPIN PRODUCING BACTERIA

Serpin protein producing Bifidobacterium longum subsp. longum and compositions thereof for use in inhibiting gluten digestion. Compositions comprising the serpin protein producing Bifidobacterium longum subsp. longum may be used to mitigate the effects of hidden gluten in individuals following a gluten free diet.

Compositions and methods to protect mammalian tissue against cold and other metabolic stresses

A composition for preserving viability of cells, tissues, or organs at a low temperature is provided. The composition includes a mitochondrial uncoupling agent, at least one protease inhibitor, and a reducing agent. Methods to protect cells, tissues, or organs from exposure to cold and other metabolic stress are also provided.

Compositions and methods to protect mammalian tissue against cold and other metabolic stresses

A composition for preserving viability of cells, tissues, or organs at a low temperature is provided. The composition includes a mitochondrial uncoupling agent, at least one protease inhibitor, and a reducing agent. Methods to protect cells, tissues, or organs from exposure to cold and other metabolic stress are also provided.

METHODS FOR TREATMENT OF DISEASES
20250228922 · 2025-07-17 ·

We describe peptides and their uses for the treatment of, e.g. acute myocardial infarction and other cytokine storm-associated conditions.

METHODS FOR TREATMENT OF DISEASES
20250228922 · 2025-07-17 ·

We describe peptides and their uses for the treatment of, e.g. acute myocardial infarction and other cytokine storm-associated conditions.

ACELLULAR PLACENTAL THERAPIES FOR NECROTIZING ENTEROCOLITIS
20220401495 · 2022-12-22 ·

A liquid formulation comprising an acellular extract of placental tissue and a solvent that may prevent the onset or reduce the symptoms of an intestinal condition in a subject when a therapeutically effective amount of the liquid formulation is delivered to a gastric system of the subject.

ACELLULAR PLACENTAL THERAPIES FOR NECROTIZING ENTEROCOLITIS
20220401495 · 2022-12-22 ·

A liquid formulation comprising an acellular extract of placental tissue and a solvent that may prevent the onset or reduce the symptoms of an intestinal condition in a subject when a therapeutically effective amount of the liquid formulation is delivered to a gastric system of the subject.

PCSK9 inhibitory polypolypeptides and methods of use

The present invention relates to PCSK9 inhibitors and methods of use thereof. Specifically, the invention relates to PCSK9 cell-based assay, PCSK9 inhibiting polypeptides and derivatives thereof. The invention includes pharmaceutical compositions comprising a PCSK9 inhibitor polypeptide together with a pharmaceutically acceptable carrier and method for treating cardiovascular disorders, hyperlipidemia, inflammatory diseases or inflammatory response to infection.

THERAPEUTIC APPROACH FOR TREATING INFLAMMATORY BOWEL DISEASE
20220395489 · 2022-12-15 ·

Provided herein are compositions and methods to that target microbial proteases to ameliorate the intestinal barrier dysfunction and restore mucosal integrity. They are useful to treat and prevent diseases and disorders caused by pathogenic bacteria in the gastrointestinal system of a subject.