A61K2236/39

COMPOSITIONS FOR THE TREATMENT OF AGE RELATED DISORDERS
20170258862 · 2017-09-14 ·

The invention is directed to compositions for the prophylaxis, treatment and recovery of age related disorders. Compositions comprising a combination of parts of plants or plant extracts belonging to Crassulaceae, Araliaceae and Schisandraceae for the prophylaxis and treatment of age related disorders.

METHODS OF TREATING TUBEROUS SCLEROSIS COMPLEX WITH CANNABIDIOL AND EVEROLIMUS

The present disclosure provides methods of treating tuberous sclerosis complex comprising administering cannabidiol and everolimus.

Method for Separating Phenolic Acid Glucoside Compounds from Diaphragma juglandis Fructu
20220041639 · 2022-02-10 ·

The disclosure discloses a method for separating phenolic acid glucoside compounds from Diaphragma juglandis Fructus, belonging to the technical field of food. The method includes the following steps: (1) extraction: crushing Diaphragma juglandis Fructus, and then extracting by using ethanol to obtain walnut ethanol extract; and (2) separation: performing column chromatography on the walnut ethanol extract obtained in step (1), sequentially eluting by using ethanol of different concentrations, purifying and eluting repeatedly, and performing separation to obtain phenolic acid glucoside compounds. The phenolic acid glucoside compounds are 2-hydroxyl-5-methoxylphenyl-O-β-D-glucopyranoside, 6-hydroxylnaphthyl-1,2-di-O-β-D-glucopyranoside and 2,6-dihydroxynaphthyl-O-β-D-glucopyranoside. Pharmacological experiments confirm that the three compounds have good antioxidant activity.

ANTI-AGING COMPOSITIONS AND USES THEREOF
20220233587 · 2022-07-28 ·

Provided herein is a composition comprising a concentrated purified plasma fraction that can be used to treat age-related disorders. Also provided herein are methods for producing a composition comprising a concentrated purified plasma fraction.

<i>Pueraria </i>flower extract rich in isoflavones and a method and application of the same

A method of preparing a Pueraria flower extract rich in isoflavones includes: grinding dry Pueraria flowers to obtain a Pueraria flower powder; adding a first 20-50% ethanol solution to form a mixture, stirring and heating the mixture at 20-80° C. for 1-4 hours, removing the first solution, adding a second 20-50% ethanol solution, stirring and heating the mixture, removing the second solution, and combining the first solution and the second solution to obtain an extract solution; filtering the extract solution to remove solids; concentrating the extract solution under vacuum to obtain a crude extract containing 10-40% solid components; adding anhydrous ethanol solution to reach an ethanol concentration of the crude extract of 75-95%, storing the crude extract at 20-30° C. for 1-4 hours; centrifuging the crude extract at a speed of 2,000-5,000 r/min to obtain a supernatant; and concentrating and spray drying to obtain the Pueraria flower extract without any purification steps.

COMPOSITION FOR IMPROVING SKIN BARRIER DAMAGE AND/OR ALLEVIATING SKIN INFLAMMATION, CONTAINING 3,5-DICAFFEOYLQUINIC ACID AS ACTIVE INGREDIENT

The present invention relates to a composition for improving skin barrier damage and/or alleviating skin inflammation, wherein 3,5-dicaffeoylquinic acid isolated from an Aster glehni (AG) extract is introduced as an active ingredient of a cosmetic composition or a pharmaceutical composition for improving skim barrier damage and alleviating skin inflammation, thereby being effective in preventing and improving atopic dermatitis.

PUERARIA FLOWER EXTRACT RICH IN ISOFLAVONES AND A METHOD AND APPLICATION OF THE SAME

A method of preparing a Pueraria flower extract rich in isoflavones includes: grinding dry Pueraria flowers to obtain a Pueraria flower powder; adding a first 20-50% ethanol solution to form a mixture, stirring and heating the mixture at 20-80° C. for 1-4 hours, removing the first solution, adding a second 20-50% ethanol solution, stirring and heating the mixture, removing the second solution, and combining the first solution and the second solution to obtain an extract solution; filtering the extract solution to remove solids; concentrating the extract solution under vacuum to obtain a crude extract containing 10-40% solid components; adding anhydrous ethanol solution to reach an ethanol concentration of the crude extract of 75-95%, storing the crude extract at 20-30° C. for 1-4 hours; centrifuging the crude extract at a speed of 2,000-5,000 r/min to obtain a supernatant; and concentrating and spray drying to obtain the Pueraria flower extract without any purification steps.

METHODS AND COMPOSITIONS COMPRISING PSYCHOACTIVE COMPOUNDS FROM PSYCHOACTIVE ORGANISMS
20210393717 · 2021-12-23 ·

This invention relates to the extraction of psychoactive compounds from organisms for use in medicine. Extraction is carried out with a strong acid or strong base to either promote or inhibit dephosphorylation. The extract in the slurry form is standardized with added excipient so that when it is dried the powdered composition has a specified total psychoactive alkaloid concentration, with a known ratio of phosphorylated to dephosphorylated psychoactive alkaloids.

METHODS AND COMPOSITIONS COMPRISING PSYCHOACTIVE COMPOUNDS FROM PSYCHOACTIVE ORGANISMS
20210393716 · 2021-12-23 ·

This invention relates to the extraction of psychoactive compounds from organisms for use in medicine. Extraction is carried out with a strong acid or strong base to either promote or inhibit dephosphorylation. The extract in the slurry form is standardized with added excipient so that when it is dried the powdered composition has a specified total psychoactive alkaloid concentration, with a known ratio of phosphorylated to dephosphorylated psychoactive alkaloids.

Application method of Dendrobium candidum in preparing medicine for treating hypertension

An application method of Dendrobium candidum in preparing a medicine for treating hypertension, includes: separately adding an adjuvant, according to a conventional medicine processing method, into Dendrobium candidum powder, or an extracting solution of Dendrobium candidum powder obtained by alcohol and water extraction, or a mixture of Dendrobium candidum powder and the extracting solution obtained by alcohol and water extraction, and preparing same as traditional Chinese medicine tablets, granules, suspended granules, pills, powder, or capsules, thereby obtaining a medicine for treating hypertension.