Patent classifications
A61K2236/55
Apparatus for preparation of pharmacologically-relevant compounds from botanical sources
In a system and process for selectively purifying various pharmacologically-relevant components of a source plant such as cannabis, an initial step provides a low-temperature, robust essential oil/terpene capture that also dehydrates and decarboxylates the starting productfresh raw cannabisby means of a vacuum-assisted microwave distillation process. By doing the terpene capture under vacuum distillation temperature may be kept low. The low distillation temperature maximizes yields of thermally-sensitive components such as terpenes and cannabinoids. The system includes an oil/water separator configured to prevent leakage of ambient air into the system.
METHOD FOR SEPARATING EIGHTEEN COMPONENTS IN TRADITIONAL CHINESE MEDICINE COMPOSITION
The disclosure provides a method for separating eighteen components in a traditional Chinese medicine composition, including: (1) preparing the traditional Chinese medicine composition into a total extract of the traditional Chinese medicine composition, separating by resin through sequentially eluting with water, 10% ethanol and 30% ethanol, and collecting the 30% ethanol eluate to obtain a 30% ethanol extract; (2) adding the 30% ethanol extract to a reverse phase silica gel ODS-AQ-HG, and separating in a medium pressure separation column to obtain differently numbered elution dry pastes; (3) dissolving the differently numbered elution dry paste with 30% methanol as a solvent, and passing the solution through a 0.45 m microporous membrane, carrying out a primary separation by high performance liquid chromatography and collecting chromatographic peaks with different retention times, and further purifying by high performance liquid chromatography; finally obtaining the components of eighteen components.
Methods to produce cannabinoid products from decarboxylated cannabinoid extracts
Various aspects of this patent application relate to methods to separate a cannabinoid molecule from other molecules of a decarboxylated cannabinoid extract.
METHOD FOR PREPARING A BOTANICAL EXTRACT OF ABSCISIC ACID
A method is for preparing a botanical extract of abscisic acid, which is obtained from plant materials that contain abscisic acid, with good yields. The extract can be a purified botanical extract of abscisic acid. A composition containing the extract can be a nutritional, pharmaceutical or cosmetic composition, and the extract can be used as a medicine.
MEDICINAL AMBROSIA PLANT EXTRACTS
Phytoceutical compositions from organic extracts of the Ambrosia maritima or Ambrosia hispida plants and uses thereof for treatment of cancers is described.
PHARMACEUTICAL COMPOSITIONS FOR THE TREATMENT OF DISEASE AND/OR SYMPTOMS IN ARTHRITIS
The invention relates to the use of a combination of cannabinoids for the treatment of pain, inflammation and/or disease modification in arthritis. Preferably the cannabinoids are selected from cannabidiol (CBD) or cannabidivarin (CBDV) and delta-9-tetrahydrocannabinol (THC) or tetrahydrocannabinovarin (THCV). More preferably the cannabinoids are in a predefined ratio by weight of less than or equal to 19:1 of CBD or CBDV to THC or THCV.
COSMETIC OR DERMATOLOGICAL PREPARATION CONTAINING AN AQUEOUS AND A LIPOPHILIC FISH EGG EXTRACT
A cosmetic or dermatological preparation that contains an aqueous and a lipophilic fish egg extract for replumping skin; for increasing the incorporation of triglycerides in adipocytes; for increasing the expression of laminin, preferably of laminin-5 and most preferably of laminin-5 sub-unit; and/or for maintaining the skin elasticity and/or resilience of human skin.
METHODS TO PRODUCE CANNABINOID PRODUCTS FROM DECARBOXYLATED CANNABINOID EXTRACTS
Various aspects of this patent application relate to methods to separate a cannabinoid molecule from other molecules of a decarboxylated cannabinoid extract.
Botanical extracts and compounds from schinus plants and methods of use
This disclosure relates to extracts from the Anacardiaceae (cashew plant family) and compositions comprising compounds contained therein. In certain embodiments, the extracts are derived from the fruit of a Schinus plant. In certain embodiments, the disclosure relates to methods of treating or preventing bacterial infections, acne, and other related uses.
CONCENTRATING CANNABINOIDS IN A LIPID SOLUTION USING MULTI-PHASE PRESSURE CYCLES
A concentrated lipid-based solution including tetrahydrocannabinol (THC) is manufactured by providing a lipid solution including an array of triglycerides, cannabinoids and water soluble contaminants in a pressure vessel. Water is added to the lipid solution to create a mixture and the pressure is increased in a first phase at a first pressure and duration and in a second phase at a second temperature and duration. The mixture is agitated to dissolve the water soluble contaminants. The mixture is cooled to cause the triglycerides and cannabinoids to solidify. The solidified triglycerides and cannabinoids, including THC, are separated to yield a purified cannabinoid solution.