A non-antimicrobial cleansing composition is disclosed comprising from about 10.0 wt. % to less than about 40 wt. % of one or more C.sub.1-C.sub.8 alcohols; about 0.5 wt. % to about 10.0 wt. % of at least one primary surfactant; 0 wt. % to about 10.0 wt. % of at least one secondary surfactant, with the primary and secondary surfactants having an HLB value greater than 8; a pH adjusting agent; and water. The composition does not achieve a microbial kill level greater than 2.0 log.

This TRPA1 activity inhibitor contains a compound represented by formula (I) wherein R.sup.1, R.sup.2, R.sup.3 and R.sup.4 each independently represent a hydrogen atom or a methyl group, and R.sup.5, R.sup.6, R.sup.7 and R.sup.8 each independently represent a hydrogen atom, a methyl group or —O—R.sup.9—OH (in the formula, R.sup.9 represents an alkylene group optionally having a substituent group), provided that at least one group of R.sup.5, R.sup.6, R.sup.7 and R.sup.8 is —O—R.sup.9—OH. ##STR00001##

The present invention relates to a solid cleanser composition including starch, sodium cocoyl isethionate, glycerin, and a conditioning agent as active ingredients. The solid cleanser composition and the method for preparing the same can prevent side effects of the skin, such as skin itching and hair loss, since not including sulfate-based surfactants, and preservatives. In addition, the solid cleanser which includes sodium cocoyl isethionate, glycerin and natural plant extracts is not easily softened and does not crumble easily to provide excellent usability, and provides excellent foaming and cleaning ability.

The-use of magnesium hydride in the preparation of a composition for preventing and treating chronic periodontitis, and a magnesium hydride toothpaste are provided. In the composition or the magnesium hydride toothpaste, magnesium hydride has a weight percentage of 1% to 3%. The toothpaste has the functions of disinfection, anti-inflammation, anti-oxidation, removing tooth stains, improving bad breath, alleviating gingival swelling, bleeding, and recession, and improving periodontitis symptoms. An appropriate amount of magnesium hydride fine particles is added in toothpaste, and the magnesium hydride particles can be hydrolyzed into hydrogen and magnesium ions with anti-inflammatory effects, which can also inhibit alveolar bone resorption. The magnesium hydride-containing composition is safe in use, and can effectively prevent the occurrence and development of periodontal diseases after long-term use.

Skin care compositions and methods are provided. In some embodiments, the skin care compositions include retinol and polydeoxyribonucleotide (PDRN). In certain embodiments, methods of using the aforementioned skin care compositions are provided as treatment for skin aging and/or acne scars.

The invention relates to O-quinone compounds of general formula (I) as agents neutralising nitric oxide, and to the therapeutic or cosmetic use thereof.

##STR00001##

The present invention provides a method of treatment of irritation of skin or mucous cells. The method comprises applying topically a composition comprising a combination of: xylitol, myonisotiol or mannitol or any combination of these; glycerol and/or urea; water; in the absence of any oil in water or wax in water emulsion.

A non-irritating topical composition for moisturizing and cleansing the skin includes: a mixture of moisturizers and conditioning agents; a mixture of surfactants; a mixture of anti-irritant agents; and a mixture of hydrating and rejuvenation agents, in an aqueous vehicle. At least one ingredient in each of the ingredient groups consisting of moisturizers and conditioning agents, surfactants, anti-irritant agents, and hydrating and rejuvenation agents is plant-derived. The composition is essentially free from any synthetic additives or by-products. The composition has a pH in the range of 5.0-8.0.

A topical pharmaceutical or composition for prevention and treatment of irritation to skin cells. The composition comprises an aqueous solution of xylitol and glycerol. In a preferred embodiment, the composition comprises 5% (w/w) xylitol, 5% (w/w) glycerol, a viscosity-enhancing agent, base to bring to the pH to 4.9, and optionally, a pharmaceutically active agent.

Provided herein is an oral care composition comprising an antioxidant and a surfactant system, wherein the surfactant system comprises sodium methyl cocoyl taurate in an amount of from 0.7 weight % to 1.2 weight % by total weight of the composition and optionally, a poloxamer in an amount of from 0.4 to 1.2 weight % by total weight of the composition. The composition is useful for preventing or treating periodontal disease.