Described herein are electrospun core-shell fibers that include (i) a central core that is electrically conductive having an exterior surface, wherein the core comprises a first polymer and an electroconductive material; (ii) a shell adjacent to the exterior surface of the core, the shell comprising a second polymer; and (iii) one or more bioactive agents in the shell. In one aspect, the fibers are electrospun fibers. Additionally, described herein are methods for making and using the core-shell fibers.

An article having anti-microbial effect is provided. The article includes an occlusive layer and a substrate having a nanostructured surface. The nanostructured surface is coated with a metal oxide layer and the metal oxide layer includes a metal oxide.

An article having anti-microbial effect is provided. The article includes an occlusive layer and a substrate having a nanostructured surface. The nanostructured surface is coated with a metal oxide layer and the metal oxide layer includes a metal oxide.

Some embodiments relate to additive manufactured articles having passivated surfaces and related methods. The methods may comprise forming a three-dimensional (3D) article by additive manufacturing to obtain an additive manufactured 3D article comprising a magnesium component. The method may further comprise exposing the additive manufactured 3D article to a reactive gas phase comprising a fluorine component. The fluorine component from the reactive gas phase may react with the magnesium component of the additive manufactured 3D article to form a passivation layer at and below a surface of the additive manufacture 3D article.

Some embodiments relate to additive manufactured articles having passivated surfaces and related methods. The methods may comprise forming a three-dimensional (3D) article by additive manufacturing to obtain an additive manufactured 3D article comprising a magnesium component. The method may further comprise exposing the additive manufactured 3D article to a reactive gas phase comprising a fluorine component. The fluorine component from the reactive gas phase may react with the magnesium component of the additive manufactured 3D article to form a passivation layer at and below a surface of the additive manufacture 3D article.

This invention relates to a pharmaceutical preparation for the treatment of compromised tissue such as skin wounds and ulcers in humans and animals and a method of preparation. This is a multifunctional natural matrix meant for the treatment of compromised tissues which also relates to the anti-cancer transdermal patch for melanoma therapy. Further, the invention comprises for the treatment of Alzheimer's, and multiple sclerosis also. The composition consists of water-solubilized nano-sized formulation of non-aqueous solvent extract of phyto-pharmaceuticals in herbal, animal or synthetic biocompatible gel or on matrix coated or both. The composition is used as a topical device for the treatment of compromised tissues in its preferred embodiment.

This invention relates to a pharmaceutical preparation for the treatment of compromised tissue such as skin wounds and ulcers in humans and animals and a method of preparation. This is a multifunctional natural matrix meant for the treatment of compromised tissues which also relates to the anti-cancer transdermal patch for melanoma therapy. Further, the invention comprises for the treatment of Alzheimer's, and multiple sclerosis also. The composition consists of water-solubilized nano-sized formulation of non-aqueous solvent extract of phyto-pharmaceuticals in herbal, animal or synthetic biocompatible gel or on matrix coated or both. The composition is used as a topical device for the treatment of compromised tissues in its preferred embodiment.

A breathable thermoplastic polymer film may be produced and adapted for use as a breathable diaper backsheet. The film may include a blend of LLDPE, mLLDPE and calcium carbonate, and may have improved tear strength and melt strength such that instances of tears or break offs during the machine direction orientation portion of the production process are significantly reduced or eliminated. In addition, the film may have sufficient tear strength to permit omission of CDI processing needed to strengthen weaker prior art films. In this regard, undesired streaking of colors or printed aspects of the film may be reduced or avoided completely.

A breathable thermoplastic polymer film may be produced and adapted for use as a breathable diaper backsheet. The film may include a blend of LLDPE, mLLDPE and calcium carbonate, and may have improved tear strength and melt strength such that instances of tears or break offs during the machine direction orientation portion of the production process are significantly reduced or eliminated. In addition, the film may have sufficient tear strength to permit omission of CDI processing needed to strengthen weaker prior art films. In this regard, undesired streaking of colors or printed aspects of the film may be reduced or avoided completely.

The present invention provides a hemostatic porous composite sponge comprising i) a matrix of a biomaterial; and ii) one hydrophilic polymeric component comprising reactive groups wherein i) and ii) are associated with each other so that the reactivity of the polymeric component is retained, wherein associated means that said polymeric component is coated onto a surface of said matrix of a biomaterial, or said matrix is impregnated with said polymeric material, or both.