The invention provides medical devices comprising high-strength alloys which degrade over time in the body of a human or animal, at controlled degradation rates, without generating emboli and which have enhanced degradation due to the presence of a halogen component. In one embodiment the alloy is formed into a bone fixation device such as an anchor, screw, plate, support or rod. In another embodiment the alloy is formed into a tissue fastening device such as staple. In yet another embodiment, the alloy is formed into a dental implant or a stent.

An exemplary valve repair device for repairing a native valve of a patient includes a coaption element, a pair of paddles, and barb portions. The barb portions extend directly from at least one of the coaption element and the pair of paddles.

An exemplary valve repair device for repairing a native valve of a patient includes a coaption element, a pair of paddles, and barb portions. The barb portions extend directly from at least one of the coaption element and the pair of paddles.

Pharmaceutical compositions comprising amphiphilic peptides are provided. The pharmaceutical compositions are useful in treating or preventing various orthopedic and dental-related infectious and/or inflammatory conditions.

The invention relates to a stent for transluminal implantation into hollow organs, in particular into blood vessels, ureters, esophagi, the colon, the duodenum, the airways or the biliary tract, comprising an at least substantially tubular body that extends along a longitudinal direction and that can be converted from a compressed state having a first cross-sectional diameter into an expanded state having an enlarged second cross-sectional diameter. The stent in accordance with the invention is characterized in that the tubular body comprises an inner body and an outer body, with the outer body surrounding the inner body at least regionally, with the outer body completely running around at least one section of the inner body, and the outer body is formed from a bioresorbable material or comprises a bioresorbable material.

A method of incorporating silver and/or copper into a biomedical implant includes: providing an implant having an outer surface; depositing silver and/or copper onto the outer surface of the implant; diffusing the silver and/or copper into a subsurface zone adjacent the outer surface; and oxidizing or anodizing the implant after the diffusion step to form an oxidized or anodized layer that contains at least some amount of elemental silver, elemental copper or silver or copper ions or compounds.

A method of incorporating silver and/or copper into a biomedical implant includes: providing an implant having an outer surface; depositing silver and/or copper onto the outer surface of the implant; diffusing the silver and/or copper into a subsurface zone adjacent the outer surface; and oxidizing or anodizing the implant after the diffusion step to form an oxidized or anodized layer that contains at least some amount of elemental silver, elemental copper or silver or copper ions or compounds.

An implantable prosthesis includes a silicone shell having an apex, a base, a radius located between the apex and the base, and a dome extending between the apex and the radius. The silicone shell has an outer surface and an inner surface that surrounds an interior volume of the silicone shell. A silicone gel material is disposed within the interior volume of the silicone shell. A gelling enhancer layer containing a gelling enhancer covers the inner surface of the silicone shell. After the silicone gel material has been thermally cured, the silicone gel material that is located within a zone that is in the vicinity of the gelling enhancer layer has a higher level of cohesiveness than the silicone gel material that is located outside the zone. The gelling enhancer contains crosslinker and/or platinum catalyst, such as a Karstedt catalyst.

Disclosed is a medical device comprising a porous structure, wherein a configuration of the porous structure varies in dependence on a load applied to the porous structure, such that the porous structure has a first configuration when the load is of a first magnitude, and has a second configuration when the load is of a second magnitude greater than the first magnitude. The porous structure comprises a first surface portion and a second surface portion. The first surface portion is disengaged from the second surface portion when the porous structure has the first configuration, and is engaged with the second surface portion when the porous structure has the second configuration.

The present invention relates to the field of medical titanium alloy materials, and in particular, to a narrow-diameter high-strength implant-specific medical titanium alloy achieving immediate implant placement and a preparation method for the implant-specific medical titanium alloy. The medical titanium alloy is prepared from the following chemical components (by weight percentage), 14%-17% of Zr, 3.0%-10% of Cu, and the balance of Ti. The preparation method for the medical titanium alloy comprises: after cogging and forging and before rolling, performing heat preservation for 0.5-6 h at the temperature of 900-1200° C., and water cooling to the room temperature; and rolling at the temperature of 720-850° C., a strain rate being larger than 0.1 s-1, and a barstock obtained after rolling being used for subsequent implant processing. According to the narrow-diameter high-strength implant-specific medical titanium alloy achieving immediate implant placement provided in the present invention, immediate implant placement can be achieved without any surface treatment, and a firm combination of the implant and a bone tissue is achieved. According to the preparation method for the medical titanium alloy provided in the present invention, the implant having a narrow diameter (3.0-3.5 mm) can be prepared and is high in strength, and the purpose of firm implanting on a narrow teethridge missing a tooth is achieved.