The present disclosure relates to a multi-chamber bioreactor, preferably in a polymeric material with a 3D structure, adapted for cell-mono and co-culture, with at least two entries and outputs of culture medium adaptable to be used as a static culture system and to incorporate a dynamic platform creating a bioreactor. The disclosure also relates to a technique based on a bioreactor device that allows the creation of two or more different tissues integrated with the natural phenotype, using an integrated and continuous 3D support structure.

The present invention relates to a composition for preserving cells and a cell preservation method and, more specifically: to a composition for preserving cells, containing, as active ingredients, a plant-derived recombinant human serum albumin and a plant peptide, which maintain a high cell survival rate while maintaining animal-free and xeno-free properties and are stable without changes in cell morphology or a surface expression factor during the short term preservation of cells such as stem cells or primary cultured cells; and a cell preservation method using the same.

The present invention relates to a composition for preserving cells and a cell preservation method and, more specifically: to a composition for preserving cells, containing, as active ingredients, a plant-derived recombinant human serum albumin and a plant peptide, which maintain a high cell survival rate while maintaining animal-free and xeno-free properties and are stable without changes in cell morphology or a surface expression factor during the short term preservation of cells such as stem cells or primary cultured cells; and a cell preservation method using the same.

An improved abdominal hernia repair system is presented comprised of a silicone layer backed up with a knitted or woven polypropylene fabric layer, the silicone layer possessing a regular pattern of slits that permit equilibration of fluid pressure across the device. A variety of therapeutic substances can be applied to the hernia repair device to promote healing, including aloe and other medicinal preparations. A layer of water soluble or water insoluble anti-scar compound is also present, the preferred compound being Salinomycin.

An improved inguinal hernia repair system is presented that is identical to the above except it does not contain the hydrophobic silicone component.

The method for producing a three-dimensional artificial tissue is a method in which a three-dimensional artificial tissue extending in a predetermined direction is produced. The method includes: preparing a device including a culture tank having a culturing space surrounded by sidewalls, and a flow channel-forming member that penetrates through the sidewalls that face each other and is suspended in the culturing space along a predetermined direction; culturing cells in the culturing space and thereby forming a three-dimensional artificial tissue through which the flow channel-forming member penetrates; and removing the flow channel-forming member from the three-dimensional artificial tissue and thereby forming a perfusion flow channel that penetrates through the three-dimensional artificial tissue.

The method for producing a three-dimensional artificial tissue is a method in which a three-dimensional artificial tissue extending in a predetermined direction is produced. The method includes: preparing a device including a culture tank having a culturing space surrounded by sidewalls, and a flow channel-forming member that penetrates through the sidewalls that face each other and is suspended in the culturing space along a predetermined direction; culturing cells in the culturing space and thereby forming a three-dimensional artificial tissue through which the flow channel-forming member penetrates; and removing the flow channel-forming member from the three-dimensional artificial tissue and thereby forming a perfusion flow channel that penetrates through the three-dimensional artificial tissue.

The invention provides engineered biomaterials derived from plant products. The engineered biomaterials are useful for biomedical applications. The engineered biomaterials are able to support the growth of animal calls.

The invention provides engineered biomaterials derived from plant products. The engineered biomaterials are useful for biomedical applications. The engineered biomaterials are able to support the growth of animal calls.

An artificial dermis repair material and a preparation method therefor. The artificial dermis repair material comprises a silicon rubber layer and a collagen complex layer adhered to each other; the collagen complex layer is prepared from raw materials comprising collagen, a mucopolysaccharide, and an antibacterial agent, which undergo a crosslinking reaction. The silicon rubber layer has high strength, high elasticity and softness, is easy to stitch, and has a good fitting performance; the collagen complex layer has good biocompatibility, degradability and an antibacterial property, and is suitable for repair and reconstruction of a dermal tissue.

An artificial dermis repair material and a preparation method therefor. The artificial dermis repair material comprises a silicon rubber layer and a collagen complex layer adhered to each other; the collagen complex layer is prepared from raw materials comprising collagen, a mucopolysaccharide, and an antibacterial agent, which undergo a crosslinking reaction. The silicon rubber layer has high strength, high elasticity and softness, is easy to stitch, and has a good fitting performance; the collagen complex layer has good biocompatibility, degradability and an antibacterial property, and is suitable for repair and reconstruction of a dermal tissue.