A medical guide wire including a core wire having a distal end-side small-diameter portion and a proximal end-side large-diameter portion, and a coil spring installed on an outer periphery of the distal end-side small-diameter portion of the core wire along an axial direction, having a front end-side small-diameter portion, a tapered portion and a rear end-side large-diameter portion, and fixed to the core wire, wherein the front end-side small-diameter portion of the coil spring has a length of 5 to 100 mm, and the outside diameter of a coil thereof is at most 0.012 inch, the front end portion of the coil spring is fixed to the core wire by a gold-containing solder, and a length of a distal end portion stiffened by the gold-containing solder is 0.1 to 0.5 mm.

Disclosed is a medical instrument coating, being coated on the surface of a nickel-titanium alloy component of a medical instrument. The medical instrument coating comprises an elementary copper phase, an amorphous titanium-containing substance and a transition layer comprising a copper-nickel intermetallic phase. Also mentioned is a preparation method for the medical instrument coating. A medical instrument comprising a copper-titanium coating has good blood compatibility, and simultaneously can inhibit the endothelialization of the medical instrument surface, thereby improving the recovery rate of the medical instrument and prolonging the recovery time window; the copper-titanium coating belongs to the group of metal composite coatings, has a certain toughness and ductility, and avoids the large-amplitude deformation process of the medical instrument damaging the coating; and the mechanical property and the coating quality of the medical instrument comprising a fine nickel-titanium alloy component are guaranteed by the method for preparing the coating.

A medical material uses a nickel-titanium alloy wherein a polyelectrolyte has a reduced thickness while a sufficient amount of an antithrombogenic compound for production of a therapeutic effect is supported. The medical material in which a porous surface is formed on a nickel-titanium alloy to allow infiltration of a polyelectrolyte into the pores, to thereby reduce the thickness of the polyelectrolyte exposed on the surface of the nickel-titanium alloy while allowing supporting of a sufficient amount of an antithrombogenic compound due to contribution of the polyelectrolyte infiltrate.

A biodegradable pressure sensor for measuring vital physiological pressures and for preventing the buildup of dangerous internal forces in impaired organs. The pressure sensor is constructed by depositing Mg or Mo on both sides of a PLLA film. This layered configuration (Mg/PLLA/Mg) or (Mo/PLLA/Mo) may then be encapsulated by layers of high molecular weight PLA. These materials are biodegradable such that after implantation, the sensor does not require invasive removal surgery that can damage directly interfaced tissues.

A medical device and a method and process for at least partially forming a medical device, which medical device has improved physical properties.

There is provided a medical instrument achieving a simple and efficient configuration. The medical instrument includes: an elongated part formed in a linear or tubular shape, at least a part of which is inserted into a living body; and an alloy part provided in the elongated part and formed from an alloy containing titanium and tantalum.

Provided herein is a drug delivery system comprising: a. substrate; b. a plurality of components combined with the substrate to form the drug delivery system; wherein at least one components comprises a bioabsorbable polymer and at least one other component comprises one or more active agents; wherein at least part of the active agent is in crystalline form.

The invention relates to a magnesium alloy containing (in % by weight) more than 0.0 to 7.0% zinc, optionally more than 0.0 to 1.0% zirconium, optionally more than 0.0 to 1.0% calcium, optionally more than 0.0 to 1.0% manganese, optionally more than 0.0 to 0.5% silicon, optionally more than 0.0 to 1.0% silver, a max. up to 0.5% aluminum and at least one element selected from the group comprising more than 0.05 to 0.6% yttrium, more than 0.05 to 4.0% ytterbium, more than 0.05 to 4.0% gadolinium, with the residue being magnesium and impurities due to production. The invention also relates to a use of a magnesium alloy of this type and an implant therefrom and a method for producing a body of a magnesium alloy according to the invention.

A vertebral fixation device and corresponding method of fixation hold a spinal vertebra on a rod. The device has a fixation element including a component of substantially U-shaped cross section with a first branch, a bottom and a second branch. A loop is formed by a flexible band for connecting the vertebra to the component, and which passes through recesses provided in the branches. Adjustable means for immobilizing the flexible band are provided. Those means include a connector screw having a head for longitudinal immobilization of the screw with respect to the first branch a thread for screwing in the second branch. A removable sleeve for passage of the screw, insertable in the first branch, in longitudinal abutment with the head of the screw is provided and presents a chamfered part designed to cooperate with the rod to compress the band between the rod and the bottom of the component.

A magnetic article with a corrosion resistant barrier formed from a poly(tetrafluoro-p-xylene) conformal coating or from a parylene conformal coating having a melting point of at least about 430° C. and a moisture vapor transmission less than about 0.5 g-mm/m.sup.2/day at 90% RH and 37° C., the conformal coating being covered with a polysulfone thermoplastic overlayer.