An expandable stent for implantation in a body lumen, such as an artery, is disclosed. The stent consists of a plurality of radially expandable cylindrical rings generally aligned on a common longitudinal stent axis and interconnected by one or more interconnecting links placed so that the stent is flexible in the longitudinal direction. The link pattern is optimized to enhance longitudinal flexibility and high longitudinal strength compression of the stent.

The present invention is intended to provide a peptide that selectively binds to a metal surface. Specifically, the present invention relates to a peptide consisting of an amino acid sequence as set forth in SEQ ID NO: 1, SEQ ID NO: 2, SEQ ID NO: 3, SEQ ID NO: 4, SEQ ID NO: 5, SEQ ID NO: 6, SEQ ID NO: 7, or SEQ ID NO: 8, or a peptide substantially identical to the aforementioned peptide, and a method for detecting a metal surface of a medical device, using these peptides.

An implant including an implant body to be inserted into biological tissue, the implant body having a hollow portion that penetrates the implant body, and an antibacterial property-imparting means that imparts an antibacterial property to at least the hollow portion of the implant body.

A surgical staple cartridge is disclosed comprising a plurality of staples removably stored within the surgical staple cartridge. The staples comprise staple legs which extend from a staple base portion. The staple legs comprise staple tips configured to pierce tissue and contact a corresponding forming pocket of an anvil of surgical stapling instrument. The staples further comprise zones having different hardnesses.

Provided herein are novel devices for the formation of arteriovenous fistulas, which may aid subjects in need of hemodialysis. The novel devices are provided in a non-surgical procedure, greatly decreasing the cost and increasing the convenience of placing an arteriovenous fistula. The devices are atraumatic, and consist of a sutureless anastomosis device and conduit. Methods and tools for placing the devices in vivo are disclosed, including a magnetic-assisted method.

Stapling devices and staple cartridges are disclosed. A stapling device can include a jaw configured to sequentially receive a plurality of dissimilar staple cartridges having different bioabsorbable components. An adjustment module can implement a firing control algorithm based on which dissimilar staple cartridge is received in the jaw. A staple cartridge can include staples comprised of a bioabsorbable metal alloy and configured to degrade at a staple degradation rate over an expected staple life in the patient. A staple cartridge can also include an implantable layer comprised of a bioabsorbable polymer and configured to degrade at a layer degradation rate over an expected layer life in the patient. The staple degradation rate and the implantable degradation rate can be different. The implantable layer can mechanically support at least a portion of a staple for a time in the expected staple life.

A method of pairing bioabsorbable staples in a staple cartridge with the tissue being treated such that the staples are structurally sufficient during the healing window of the tissue but completely bioabsorb shortly thereafter.

Provided are orthopedic implants and systems and kits containing orthopedic implants that include biodegradable polymer thin films containing an antimicrobial agent, wherein the implants produce an effective zone of inhibition around a periphery of the surface of the implant and do not produce a loss of release torque between interlocking implant components.

A medical device that is at least partially formed of a refractory metal alloy, and a method for inserting the medical device in a patient.

The invention relates to biodegradable iron alloy-containing compositions for use in preparing medical devices. In addition, biodegradable crystalline and amorphous compositions of the invention exhibit properties that make them suitable for use as medical devices for implantation into a body of a patient. The compositions include elemental iron and one or more elements selected from manganese, magnesium, zirconium, zinc and calcium. The compositions can be prepared using a high energy milling technique. The resulting compositions and the devices formed therefrom are useful in various surgical procedures, such as but not limited to orthopedic, craniofacial and cardiovascular.