An in-vivo implantable electronic device includes a housing, a power reception coil, and an electronic circuit. The housing is formed of a biocompatible material and forms an internal space sealed. The power reception coil is disposed in the internal space of the housing and receives power by interacting with an electromagnetic field formed by an external electric field or magnetic field, or transmits an electromagnetic wave to the outside. The electronic circuit is disposed in the internal space, is connected to the power reception coil, and performs at least processing of an electric signal. The housing includes a first member in a box shape formed of a biocompatible metal material and having an opening, a second member formed of a biocompatible nonmetal material and having a shape that closes the opening, a packing in an annular shape disposed between the first member and the second member.

An in-vivo implantable medical device includes a housing, an electronic circuit component, a power reception coil, and a magnetic material. The housing is formed of a biocompatible material and forms an internal space. The electronic circuit component is disposed in the internal space. The power reception coil is disposed in the internal space, interacts with an external electromagnetic field to form an electromagnetic resonance field to receive power. At least part of a region of the housing in which the electromagnetic resonance field is formed is formed of a biocompatible nonmetal material.

A method of coating a slip ring for use with a surgical instrument is disclosed. The method includes the steps of providing a slip ring including a plurality of conductive elements, and depositing a material less conductive than the conductive elements onto the conductive elements of the slip ring.

A method for preventing contamination of a substrate surface includes obtaining a substrate having a surface to be protected from contamination and depositing a removable protective salt coating on the substrate surface. A disclosed method also includes storing the substrate surface having the removable protective salt coating for a time period and then removing the protective salt coating. A method for selectively preventing atomic layer deposition (ALD) on a substrate surface exposed to an ALD process includes depositing a removable protective salt coating on the substrate surface, exposing the surface to an ALD process, and removing the protective salt coating. Some disclosed substrate surfaces include a thiol-on-gold monolayer, a silicon wafer, glass, a silanized surface, and a dental implant. The protective salt coating may have a thickness in the range of 50 nm to 1 μm. The protective salt coating may be deposited by thermal evaporation or similar process.

Provided is a nasal implant assembly comprising a hollow implant having a distal end and a proximal end, the distal end configured to have a segment deposited with magnetic particles; and a medical syringe configured to be attachable to the proximal end of the hollow implant and also configured to be capable of retaining and transporting a magnetically active fluid composition through the implant to a nasal cavity of a subject. Also provided is a method of treating chronic rhinosinusitis in a subject, the method comprising the steps of positioning a nasal implant having magnetic particles into a nasal cavity; loading a medical syringe with a magnetically active fluid composition; and transporting the loaded magnetically active fluid composition to the nasal cavity to treat chronic rhinosinusitis.

A biomedical device including an energy source, an electro-active device operatively connected to the energy source, circuitry configured to control operation of the electro-active device, at least one barrier layer including at least one inorganic material surrounding the energy source, electro-active device and circuitry, and at least one molded layer surrounding the at least one barrier layer. A method for encapsulating electronic components of an electro-active biomedical device in a protective envelope containing a barrier layer including at least one inorganic compound, and a molded polymer overcoat.

An antimicrobial layered body includes: a non-metal substrate; and a metal oxide layer, in which the metal oxide layer is present on an outermost surface, the metal oxide layer contains an anion, and a total abundance ratio of at least one atom of a sulfur atom, a phosphorus atom, and a carbon atom which are derived from the anion is 1.0 atm % or more when analyzed by XPS.

An absorbable iron-based alloy implantable medical device includes an iron-based alloy matrix, a degradable polymer coating disposed on the surface of the iron-based alloy matrix, and a corrosion inhibition layer disposed on the surface of the iron-based alloy matrix. The corrosion inhibition layer can delay early-stage corrosion of the iron-based alloy matrix, ensure mechanical performance of a medical device in the early stage of the implantation, prevent degradation of a polymer in the early stage of the implantation of the medical device, and reduce the usage of the degradable polymer, thereby reducing risks of inflammatory reactions.

A method of coating a slip ring for use with a surgical instrument is disclosed. The method includes the steps of providing a slip ring including a plurality of conductive elements, and depositing a material less conductive than the conductive elements onto the conductive elements of the slip ring.

An implantable drug-loaded device, including a zinc-containing matrix and an active drug layer attached to the zinc-containing matrix. In the zinc-containing matrix per unit area, the content of an active drug is (g.Math.mm.sup.2). The content of zinc corroded from the zinc-containing matrix per unit area in a guaranteed grade acetic acid aqueous solution at 8.3 vol % within unit time is p (g.Math.mm.sup.2.Math.min.sup.1). The value of and the value of p satisfy the following relation: 0.115p+3.5, where p is greater than or equal to 0.005 and less than or equal to 0.14. The zinc release rate of the implantable drug-loaded device is matched with the content of the active drug, so after the implantable drug-loaded device is implanted into a body, the zinc and the drug work synergistically to effectively inhibit smooth muscle cell proliferation, and cannot kill cells and cause necrosis in tissues.