Cleaning systems and methods, wherein the system includes a chamber configured to receive a body part of a user or an object, where the user's skin or object is exposed to one or more cleaning, disinfecting and/or sterilizing processes, such as chemical agents, mechanical energy, ultraviolet light, and ultrasound, to clean, disinfect and/or sterilize the skin or object.

A medical intervention assistance robot is described. The medical intervention assistance robot comprises a first operating arm configured to handle a non-sterile object, a second operating arm configured to handle a sterile object and a support unit configured to support the first operating arm and the second operating arm. The medical intervention assistance robot also comprises a control unit configured to control a movement of the first operating arm and a movement of the second operating arm. Further, a medical intervention method using a medical intervention assistance robot is described.

A cap is described for connection to a needleless connector having an open lumen, the cap includes a housing having a top wall and sidewall forming a first cavity, a flexible container, an porous absorbent material and a sealing rubber. The flexible container includes an inner thread on an inner surface, the inner thread being sufficient to interlock with a mating feature of a female needleless connector. The inner surface of the flexible container defines a second cavity. The sidewall of the housing having a split-thread protrusion integrally formed with the distal wall, an outer thread disposed on an outer surface of the split-thread protrusion, the outer thread being sufficient to interlock with a mating feature of a male needleless connector. The second cavity configured to define a chamber to contain an absorbent reservoir material, a sealing rubber and disinfectant or antimicrobial agent.

Disinfecting apparatus and method. The apparatus may include an enclosure configured to receive a device to be at least partially disinfected; an inlet port operably positioned with respect to the enclosure and configured to receive a disinfectant agent from a source and guide the disinfectant agent to at least partially disinfect the device, and an outlet port including a filter portion to at least minimize an amount of disinfectant agent that exits the enclosure.

The present disclosure provides on-demand agent dispensing patches, kits and related methods. A flexible patch is configured to provide on-demand dispensing of the agent via compression of the patch. The patch comprises: an adhesive layer to removably couple the patch to a surface; at least one reservoir layer overlying the adhesive layer configured to absorb and retain the agent therein; at least one dispenser layer overlying the at least one reservoir layer comprising a plurality of solid portions and an array of a plurality of openings configured to inhibit evaporation of the agent and control a flow of the agent therefrom upon the compression of the patch; and at least one backer layer between the adhesive layer and the at least one reservoir layer being substantially impervious to the agent. The at least one reservoir layer may be void of the agent, which may be provided in a container.

Disclosed are compositions comprising Rhamnus prinoides (GESHO) extract or fragments thereof and methods of using Gesho extract for the inhibition of biofilm formation.

A reusable urinary catheter assembly comprises a storage container defining a cavity, a hydration liquid and a reusable urinary catheter. The hydration liquid includes a disinfection medium and a hydrophilic polymer. The viscosity of the hydration liquid is 40 cP or lower. The reusable urinary catheter includes a shaft, and at least a part of the shaft is provided with a hydrophilic surface. During storage, the shaft is enclosed within the cavity in a storage position. The hydration fluid hydrates and regenerates the hydrophilic surface and disinfects the catheter. The catheter is configured to be repeatedly inserted into and removed from the storage container.

A handle for an oral-care implement, the handle comprises an electrical motor arranged to drive an output element structured and configured to couple the handle and a head attachable to and detachable from the handle; and a microcontroller for controlling the motor and to cause the output element to vibrate in (a) at least one oral-hygiene mode during which the oral-care implement is being used for an oral-hygiene routine, wherein the output element is vibrating at a substantially constant frequency, and (b) a disinfection mode during which the handle is being disinfected, before or after being used for the oral-hygiene routine, wherein the output element is continuously vibrating at a modulated frequency alternating within a frequency range of between about 140 Hz and about 250 Hz, for a duration of the disinfection mode.

A cap is described for connection to a needleless connector having an open lumen, the cap includes a housing having a top wall and sidewall forming a first cavity, a flexible container, an porous absorbent material and a sealing rubber. The flexible container includes an inner thread on an inner surface, the inner thread being sufficient to interlock with a mating feature of a female needleless connector. The inner surface of the flexible container defines a second cavity. The sidewall of the housing having a split-thread protrusion integrally formed with the distal wall, an outer thread disposed on an outer surface of the split-thread protrusion, the outer thread being sufficient to interlock with a mating feature of a male needleless connector. The second cavity configured to define a chamber to contain an absorbent reservoir material, a sealing rubber and disinfectant or antimicrobial agent.

A method of sterilizing biological tissue such as soft mammalian tissue that can be used to make bioprosthetic devices is disclosed. The method comprises contacting biological tissue with a bioburden reduction mixture, contacting biological tissue with a tissue drying mixture, and thereafter sterilizing the dry tissue with supercritical carbon dioxide. Prior to sterilizing the biological tissue with supercritical carbon dioxide, the biological tissue is placed under vacuum and, in some embodiments, is treated with a vaporized microbicide. Bioprosthetic devices made using the methods disclosed herein include bioprosthetic heart valves, biological tissue derived vascular grafts or vessels, and surgical tissue patches.